N-hepta-O-acetyl-β-D-lactosyl isocyanodichloride | 1401071-59-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-hepta-O-acetyl-β-D-lactosyl isocyanodichloride
• CAS: 1401071-59-7
• 化学式: C₂₇H₃₅Cl₂NO₁₇
• 分子量: 716.477
• InChiKey: NDNHPPAFWDBJJZ-LTSQYKSLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.44
• 重原子数：
  47.0
• 可旋转键数：
  12.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  224.15
• 氢给体数：
  0.0
• 氢受体数：
  18.0

反应信息

• 作为反应物：
  描述：

  C₂₂H₂₁N₃S₂ 、 N-hepta-O-acetyl-β-D-lactosyl isocyanodichloride 以 氯仿 为溶剂， 反应 3.0h， 以86.36%的产率得到
  参考文献：
  名称：

  Synthesis and in Vitro Antimicrobial Activity of 3-Aryl-4-S-benzyl-6-phenylimino-2-hepta-O-acetyl-β-D-lactosylimino-2,3-dihydro-1,3,5-thiadiazine (Hydrochloride)

  摘要：

  The present work includes synthesis of several 3-aryl-4-S-benzyl-6-phenylimino-2-hepta-O-acetyl-beta-D-lactosylimino-2,3-dihydro-1,3,5-thiadiazines (hydrochloride) by the interaction of N-hepta-O-acetyl-b-D-lactosyl isocyanodichloride and 1-aryl-5-phenyl-2-S-benzyl-2,4-isodithiobiurets. All these products have been characterized through the usual chemical transformations and infrared, H-1 NMR, and mass spectral analysis. The compounds were also screened for their antimicrobial activities.

  DOI：

  10.1080/00397911.2011.592625
• 作为产物：
  描述：

  2,3,6,2',3',4'6'-hepta-O-acetyl-β-D-lactopyranosyl isothiocianate 在 氯 作用下， 以 氯仿 为溶剂， 生成 N-hepta-O-acetyl-β-D-lactosyl isocyanodichloride
  参考文献：
  名称：

  Synthesis and in Vitro Antimicrobial Activity of 3-Aryl-4-S-benzyl-6-phenylimino-2-hepta-O-acetyl-β-D-lactosylimino-2,3-dihydro-1,3,5-thiadiazine (Hydrochloride)

  摘要：

  The present work includes synthesis of several 3-aryl-4-S-benzyl-6-phenylimino-2-hepta-O-acetyl-beta-D-lactosylimino-2,3-dihydro-1,3,5-thiadiazines (hydrochloride) by the interaction of N-hepta-O-acetyl-b-D-lactosyl isocyanodichloride and 1-aryl-5-phenyl-2-S-benzyl-2,4-isodithiobiurets. All these products have been characterized through the usual chemical transformations and infrared, H-1 NMR, and mass spectral analysis. The compounds were also screened for their antimicrobial activities.

  DOI：

  10.1080/00397911.2011.592625