| 1070974-48-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1070974-48-9
• 化学式: C₂₄H₄₆O₁₆S₂
• 分子量: 654.752
• InChiKey: UESSOLHDISTFBL-PUYHWVFISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.93
• 重原子数：
  42.0
• 可旋转键数：
  23.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  235.68
• 氢给体数：
  8.0
• 氢受体数：
  18.0

反应信息

• 作为产物：
  描述：

  2-(2-(2-thioacetylethoxy)ethoxy)ethoxy-2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside 在 sodium methylate 作用下， 以 甲醇 为溶剂， 以98%的产率得到
  参考文献：
  名称：

  Bacterial detection using carbohydrate-functionalised CdS quantum dots: a model study exploiting E. coli recognition of mannosides

  摘要：

  Mannose-coated CdS quantum dots (Man-QDs) were prepared in a facile aqueous, one-pot process that exploits the self-assembly of thiolated mannose in the presence of CdS under reducing conditions. The resulting similar to 15 nm diameter nanoparticles produce an intense, broad luminescence emission centred at 550 nm. These Man-QDs induce luminescent aggregates of Escherichia coli which can be used to detect bacteria in cell suspensions containing as few as 10(4) E. coli per mL. The aggregation process is dependent on the E coli cell surface FimH mannose-specific lectin. The recognition and subsequent detection of the E. coli using the Man-QD has been shown to be specific as aggregation does not occur either with an E. coli strain defective in the FimH lectin or with galactose-coated QDs. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.12.029