2-[2-fluoro-6-(8-fluoro-quinolin-3-yloxy)-phenyl]-3,3-dimethyl-butan-2-ol | 1314007-32-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-fluoro-6-(8-fluoro-quinolin-3-yloxy)-phenyl]-3,3-dimethyl-butan-2-ol
• 英文别名: 2-[2-fluoro-6-(8-fluoroquinolin-3-yloxy)phenyl]-3,3-dimethylbutan-2-ol；2-[2-Fluoro-6-(8-fluoro-quinolin-3-yloxy)-phenyl]-3,3-dimethylbutan-2-ol；2-[2-fluoro-6-(8-fluoroquinolin-3-yl)oxyphenyl]-3,3-dimethylbutan-2-ol
• CAS: 1314007-32-3
• 化学式: C₂₁H₂₁F₂NO₂
• 分子量: 357.4
• InChiKey: YXEKVDRDMXAPRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  42.4
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1-[2-fluoro-6-(8-fluoro-quinolin-3-yloxy)-phenyl]-ethanone 、 叔丁基氯化镁 在 盐酸 作用下， 以 四氢呋喃 、 乙醚 、 水 为溶剂， 生成 2-[2-fluoro-6-(8-fluoro-quinolin-3-yloxy)-phenyl]-3,3-dimethyl-butan-2-ol
  参考文献：
  名称：

  NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND AGRICULTURAL FUNGICIDE

  摘要：

  提供的是一种农业杀菌剂，其中至少包含一种从以下组中选择的新型含氮杂环化合物，该化合物由式（I）表示，或其盐，或其N-氧化物化合物。在式（I）中，R代表由CR1R2R3表示的基团或氰基。R1至R3分别代表氢原子，未取代或取代的C1-8烷基基团，未取代或取代的羟基团等。R4或R5代表卤素基团等。Y或Z代表碳原子等，A或D代表苯环等。X代表氧原子或氮原子等。

  公开号：

  US20120289702A1

文献信息

• Nitrogen-containing heterocyclic compound and agricultural fungicide
  申请人：Shibayama Kotaro

  公开号：US08772200B2

  公开（公告）日：2014-07-08

  Provided is an agricultural fungicide that contains at least one selected from the group consisting of a novel nitrogen-containing heterocyclic compound represented by Formula (I), a salt thereof, or an N-oxide compound thereof. In Formula (I), R represents a group represented by CR1R2R3 or a cyano group. R1 to R3 each independently represents a hydrogen atom, an unsubstituted or substituted C1-8 alkyl group, an unsubstituted or substituted hydroxyl group, or the like. R4 or R5 represents a halogeno group or the like. Y or Z represents a carbon atom or the like, and A or D represents a benzene ring or the like. X represents an oxygen atom or a nitrogen atom or the like.

  提供一种农业杀菌剂，其中包含至少一种从以下组中选择的新型含氮杂环化合物，其化学式表示为（I），其盐或N-氧化物化合物。在化学式（I）中，R代表CR1R2R3或氰基表示的基团。R1到R3分别独立地表示氢原子，未取代或取代的C1-8烷基，未取代或取代的羟基或类似基团。R4或R5表示卤素基团或类似基团。Y或Z表示碳原子或类似基团，A或D表示苯环或类似基团。X表示氧原子或氮原子或类似基团。
• NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND AGRICULTURAL/HORTICULTURAL GERMICIDE
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2522658A1

  公开（公告）日：2012-11-14

  Provided is an agricultural fungicide that contains at least one selected from the group consisting of a novel nitrogen-containing heterocyclic compound represented by Formula (I), a salt thereof, or an N-oxide compound thereof. In Formula (I), R represents a group represented by CR1R2R3 or a cyano group. R1 to R3 each independently represents a hydrogen atom, an unsubstituted or substituted C1-8 alkyl group, an unsubstituted or substituted hydroxyl group, or the like. R4 or R5 represents a halogeno group or the like. Y or Z represents a carbon atom or the like, and A or D represents a benzene ring or the like. X represents an oxygen atom or a nitrogen atom or the like.

  本发明提供了一种农用杀菌剂，它含有至少一种选自由式（I）代表的新型含氮杂环化合物、其盐或其 N-氧化物化合物组成的组。在式 (I) 中，R 代表 CR1R2R3 所代表的基团或氰基。R1 至 R3 各自独立地代表氢原子、未取代或取代的 C1-8 烷基、未取代或取代的羟基或类似基团。R4 或 R5 代表卤素基团或类似基团。Y 或 Z 代表碳原子或类似物，A 或 D 代表苯环或类似物。X 代表氧原子或氮原子或类似物。
• AGRICULTURAL AND HORTICULTURAL GERMICIDE COMPOSITION
  申请人：Nippon Soda Co., Ltd.

  公开号：EP3760044A1

  公开（公告）日：2021-01-06

  It is an object of the present invention to provide an agricultural and horticultural fungicide composition that exhibits an excellent control effect on plant diseases even in a small dose and causes no fear of phytotoxicity to useful plants. The agricultural and horticultural fungicide composition of the present invention comprises at least one compound A selected from the group consisting of a compound of formula (1) wherein each X independently is a halogeno group or a C1-6 alkyl group; n is the number of X and is any integer of 0 to 5; X' is a halogeno group; R1, R2 and R3 each independently are a C1-6 alkyl group, a C1-6 alkoxy group or a hydroxyl group; and A1 and A2 each independently are a nitrogen atom or a carbon atom}, and the like, and at least one compound B selected from the group consisting of silthiofam, an antibiotic, propineb and chinomethionat.

  本发明的目的是提供一种农业和园艺杀真菌剂组合物，该组合物即使在小剂量下也能对植物病害表现出极佳的防治效果，并且不用担心对有用植物产生植物毒性。本发明的农业和园艺杀真菌剂组合物包括至少一种选自由式（1）其中每个 X 独立地为卤代基团或 C1-6 烷基；n 为 X 的数目，为 0 至 5 的任意整数；X'为卤代基团；R1、R2 和 R3 各自独立地为一个 C1-6 烷基、一个 C1-6 烷氧基或一个羟基；以及 A1 和 A2 各自独立地为一个氮原子或一个碳原子}等，以及至少一种选自硅噻吩、抗生素、丙氨酚和喹莫特的化合物 B。
• AGRICULTURAL AND HORTICULTURAL FUNGICIDE COMPOSITION
  申请人：Nippon Soda Co., Ltd.

  公开号：US20200352168A1

  公开（公告）日：2020-11-12

  It is an object of the present invention to provide an agricultural and horticultural fungicide composition that exhibits an excellent control effect on plant diseases even in a small dose and causes no fear of phytotoxicity to useful plants. The agricultural and horticultural fungicide composition of the present invention comprises at least one compound A selected from the group consisting of a compound of formula (1) wherein each X independently is a halogeno group or a C1-6 alkyl group; n is the number of X and is any integer of 0 to 5; X′ is a halogeno group; R 1 , R 2 and R 3 each independently are a C1-6 alkyl group, a C1-6 alkoxy group or a hydroxyl group; and A 1 and A 2 each independently are a nitrogen atom or a carbon atom}, and the like, and at least one compound B selected from the group consisting of silthiofam, an antibiotic, propineb and chinomethionat.
• US8772200B2
  申请人：——

  公开号：US8772200B2

  公开（公告）日：2014-07-08