3-aminopropyl α-L-arabinofuranosyl-(1->3)-β-D-galactopyranosyl-(1->6)-β-D-galactopyranosyl-(1->6)-[α-L-arabinofuranosyl-(1->3)]-β-D-galactopyranosyl-(1->6)-β-D-galactopyranoside | 1190749-55-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-aminopropyl α-L-arabinofuranosyl-(1->3)-β-D-galactopyranosyl-(1->6)-β-D-galactopyranosyl-(1->6)-[α-L-arabinofuranosyl-(1->3)]-β-D-galactopyranosyl-(1->6)-β-D-galactopyranoside
• 英文别名: (2R,3R,4S,5R,6R)-2-[[(2R,3S,4S,5R,6R)-6-[[(2R,3R,4S,5R,6R)-6-(3-aminopropoxy)-3,4,5-trihydroxyoxan-2-yl]methoxy]-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3,5-dihydroxyoxan-2-yl]methoxy]-6-[[(2R,3R,4S,5S,6R)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxane-3,4,5-triol
• CAS: 1190749-55-3
• 化学式: C₃₇H₆₅NO₂₉
• 分子量: 987.912
• InChiKey: XHIDLORIBSTXGD-WIMJLCSOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -11
• 重原子数：
  67
• 可旋转键数：
  20
• 环数：
  6.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  481
• 氢给体数：
  18
• 氢受体数：
  30

反应信息

• 作为产物：
  描述：

  3-azidopropyl α-L-arabinofuranosyl-(1->3)-β-D-galactopyranosyl-(1->6)-β-D-galactopyranosyl-(1->6)-[α-L-arabinofuranosyl-(1->3)]-β-D-galactopyranosyl-(1->6)-β-D-galactopyranoside 在 10% palladium on activated carbon 、 氢气 作用下， 以 水 为溶剂， 反应 2.0h， 以86%的产率得到3-aminopropyl α-L-arabinofuranosyl-(1->3)-β-D-galactopyranosyl-(1->6)-β-D-galactopyranosyl-(1->6)-[α-L-arabinofuranosyl-(1->3)]-β-D-galactopyranosyl-(1->6)-β-D-galactopyranoside
  参考文献：
  名称：

  Synthesis of 3,6-branched arabinogalactan-type tetra- and hexasaccharides for characterization of monoclonal antibodies

  摘要：

  Synthesis of tetra- and hexasaccharides built up from a beta-(1 -> 6)-linked galactopyranosyl backbone with arabinofuranosyl side chains at position 3 and with a 3-aminopropyl spacer related to arabinogalactans is described. These oligosaccharides were prepared for investigation of monoclonal antibodies raised against arabinogalactan proteins (AGPs) from pressed juice of Echinacea purpurea. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.04.025