6^I-[N'-(3-methoxypropyl)ureido]-6-^II-VII-hexaazido-6^I-VII-heptadeoxy-2^I-VII,3^I-VII-tetradeca-O-methylcyclomaltoheptaose | 1429125-60-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6^I-[N'-(3-methoxypropyl)ureido]-6-^II-VII-hexaazido-6^I-VII-heptadeoxy-2^I-VII,3^I-VII-tetradeca-O-methylcyclomaltoheptaose
• CAS: 1429125-60-9
• 化学式: C₆₁H₁₀₂N₂₀O₃₀
• 分子量: 1595.6
• InChiKey: TZPRICONFAWMSL-DICZWJJESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.18
• 重原子数：
  111.0
• 可旋转键数：
  32.0
• 环数：
  21.0
• sp3杂化的碳原子比例：
  0.98
• 拓扑面积：
  601.36
• 氢给体数：
  2.0
• 氢受体数：
  36.0

反应信息

• 作为产物：
  描述：

  在 甲醇 、 溶剂黄146 作用下， 反应 0.08h， 以21 mg的产率得到6^I-[N'-(3-methoxypropyl)ureido]-6-^II-VII-hexaazido-6^I-VII-heptadeoxy-2^I-VII,3^I-VII-tetradeca-O-methylcyclomaltoheptaose
  参考文献：
  名称：

  Implementing the “Catch-and-Release” Concept into a Simple Method for Regioselective Cyclodextrin Modification

  摘要：

  Differentiation of specific positions in axial-symmetrical cyclodextrins (CDs), exhibiting a dense display of identical functional groups, is challenging. A novel strategy toward this goal that exploits a solid matrix to display the complementary reagent functionalities sufficiently far from each other to prevent CDs from reacting through more than one site is reported. Using a "catch-and-release" process based on the Staudinger reaction, the utility of this concept to easily produce complex CD functionalization patterns in one pot and without any purification step is demonstrated.

  DOI：

  10.1021/ol400641n