5,7-Dihydroxyadamantan-2-one | 28558-20-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,7-Dihydroxyadamantan-2-one
• 英文别名: 1,3-Dihydroxyadamantan-2-on
• CAS: 28558-20-5
• 化学式: C₁₀H₁₄O₃
• 分子量: 182.219
• InChiKey: VZHFKEKICMAGLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,3,6-Tribromadamantan 在 jones' reagent 、 silver(II) sulfate 作用下， 以 硫酸 、 丙酮 为溶剂， 反应 3.0h， 生成 5,7-Dihydroxyadamantan-2-one
  参考文献：
  名称：

  Face selection in the reduction of p,p'-disubstituted 5,7-diphenyl-2-adamantanones and hydrolysis of the corresponding 2-adamantyl tosylates

  摘要：

  The reduction of 5,7-diphenyl-2-adamantanone with sodium borohydride in 2-propanol is affected by the introduction of a p-nitro substituent in one of the rings: the E-alcohol is obtained in small but easily measurable excess of 1.30:1. Conversely, the introduction of a p-amino group leads to an excess of Z-isomer by roughly the same factor (1.28). When both substituents are present, they evidently cooperate to produce a ratio of 1.64. The tosylates of the alcohols were prepared and their solvolysis rates measured in 3% aqueous hexafluoro-2-propanol and compared with those of the parent and p-substituted 5-phenyl-2-adamantyl tosylates. Additivity of substituent effects was again observed, but the p-aminophenyl group in these reactions was deactivating compared to phenyl, presumably due to II-bonding and/or protonation of the amino group in the acidic medium.

  DOI：

  10.1021/jo00080a012

文献信息

• Aspects of the 2,3-trimethylenenorbornane-adamantane rearrangement
  作者：H. Hamill、A. Karim、M.A. McKervey

  DOI：10.1016/s0040-4020(01)91642-4

  日期：1971.1

  5,6,7-hexabromonaphthalene; intermediate products of the reaction could not be detected. Methods for the selective bridgehead mono- and dichlorination of adamantane and 1-methyladamantane are described. Hydrolysis of 1,3-dichloroadamantane and 5-methyl-1,3-dichloroadamantane with sodium hydroxide at 180° proceeds via fragmentation, giving bicyclo[3.3.1]nonane derivatives.

  外-或内-2,3-三亚甲基降冰片烷的溴化铝催化溴化反应可得到1,3,6-三溴金刚烷，1,3,5-三溴金刚烷和1,2,3,5,6,7-六溴萘; 无法检测到反应的中间产物。描述了金刚烷和1-甲基金刚烷选择性桥头单氯化和二氯化的方法。用氢氧化钠在180°下水解1，3-二氯金刚烷和5-甲基-1，3-二氯金刚烷，通过断裂进行水解，得到双环[3.3.1]壬烷衍生物。
• Resin useful for resist, resist composition and pattern forming process using the same
  申请人：KABUSHIKI KAISHA TOSHIBA

  公开号：US20020098441A1

  公开（公告）日：2002-07-25

  According to the present invention, a resist resin having in its structure a specific bridged-bond-containing aliphatic ring, and a resist composition comprising the same are provided. By using this resist composition, a resist pattern excellent in both transparency against short-wavelength light and dry-etching resistance can be formed by alkali development with high resolution.

  根据本发明，提供了一种在其结构中具有特定桥式键含有的脂环的抗蚀树脂，以及包括该树脂的抗蚀组合物。通过使用这种抗蚀组合物，可以通过高分辨率的碱性显影形成对短波长光具有优异透明度和干法刻蚀抗性的抗蚀图案。
• 4-Oxatricyclo(4.3.1.1-3,8)undecan-5-one derivatives and process for producing the same
  申请人：Daicel Chemical Industries, Ltd.

  公开号：EP1081150A1

  公开（公告）日：2001-03-07

  A 4-oxatricyclo[4.3.1.13,8]undecan-5-one derivative is shown by the following formula (1): wherein R is a hydrogen atom or a (meth)acryloyl group, and carbon atoms constituting a ring may have a substituent in addition to the substituents indicated in the formula. This compound is a novel 4-oxatricyclo[4.3.1.13,8]undecan-5-one derivative having a hydroxyl group or a (meth)acryloyloxy group at the 1-position.

  4-oxatricyclo[4.3.1.13,8]undecan-5-one 衍生物如下式（1）所示： 其中 R 是氢原子或（甲基）丙烯酰基，而构成环的碳原子除了具有式中所示的取代基外，还可以具有一个取代基。该化合物是一种新型 4-氧杂三环[4.3.1.13,8]十一烷-5-酮衍生物，在 1 位上具有羟基或（甲基）丙烯酰氧基。
• STETTER H.; LENNARTZ J., J. LIEBIGS ANN. CHEM., 1977, NO 11-12, 1807-1816
  作者：STETTER H.、 LENNARTZ J.

  DOI：——

  日期：——
• CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES
  申请人：TROPIX, INC.

  公开号：EP0497972A1

  公开（公告）日：1992-08-12