| 410084-53-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 410084-53-6
• 化学式: C₄₂H₆₀N₄O₂₄
• 分子量: 1004.95
• InChiKey: OFCFYIQJFADUPA-IFIBWAKHSA-N

反应信息

• 作为反应物：
  描述：

  以 水 为溶剂， 生成
  参考文献：
  名称：

  Photoswitchable Multivalent Sugar Ligands:  Synthesis, Isomerization, and Lectin Binding Studies of Azobenzene−Glycopyranoside Derivatives

  摘要：

  Coating of azobenzene chromophore with multivalent sugar ligands has been accomplished. Such sugar coating allows the study of the isomerization properties of this chromophore in aqueous solutions. The predominantly cis-isomer-containing photostationary state (PS) mixture of these azobenzene derivatives is found to be stable for hours. The rate constants for their isomerization, as well as the Arrhenius activation energies, are determined experimentally. An assessment of the lectin binding properties of the lactoside bearing isomeric azobenzene derivatives, by isothermal calorimetric methods, reveals the existence of an unusual cooperativity in their binding to lectin peanut agglutinin. Thermodynamic parameters evaluated for the trans and the PS mixture are discussed, in detail, for the lactoside bearing bivalent azobenzene derivative.

  DOI：

  10.1021/ja0173066
• 作为产物：
  描述：

  在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 12.0h， 生成
  参考文献：
  名称：

  Photoswitchable Multivalent Sugar Ligands:  Synthesis, Isomerization, and Lectin Binding Studies of Azobenzene−Glycopyranoside Derivatives

  摘要：

  Coating of azobenzene chromophore with multivalent sugar ligands has been accomplished. Such sugar coating allows the study of the isomerization properties of this chromophore in aqueous solutions. The predominantly cis-isomer-containing photostationary state (PS) mixture of these azobenzene derivatives is found to be stable for hours. The rate constants for their isomerization, as well as the Arrhenius activation energies, are determined experimentally. An assessment of the lectin binding properties of the lactoside bearing isomeric azobenzene derivatives, by isothermal calorimetric methods, reveals the existence of an unusual cooperativity in their binding to lectin peanut agglutinin. Thermodynamic parameters evaluated for the trans and the PS mixture are discussed, in detail, for the lactoside bearing bivalent azobenzene derivative.

  DOI：

  10.1021/ja0173066