4-甲氧基-5-甲基辛-1-烯 | 90246-14-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-甲氧基-5-甲基辛-1-烯
• 英文名称: 4-Methoxy-5-methyl-1-octene
• 英文别名: 4-Methoxy-5-methyloct-1-ene
• CAS: 90246-14-3
• 化学式: C₁₀H₂₀O
• 分子量: 156.268
• InChiKey: NFKWZYKXPGLUQX-UHFFFAOYSA-N

物化性质

• 沸点：
  177.4±19.0 °C(Predicted)
• 密度：
  0.798±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  lithium n-butyltriallylborate 、 1,1-dimethoxy-2-methylpentane 在 三氟甲磺酸三甲基硅酯 作用下， 以 四氢呋喃 为溶剂， 以70%的产率得到4-甲氧基-5-甲基辛-1-烯
  参考文献：
  名称：

  Allylation using allyborates

  摘要：

  A study has been carried out on the scope of allylation of a range of acetals activated by trimethylsilyl trfluoromethanesulfonate (TMSOTf) using a humber of organoborates. Intermolecular allylation of acyclic acetals proceeds smoothly and in high yield using lithium n-butyltriallylborate or lithium methyltriallylborate in THF at -78 degrees C while 1,3-dioxanes and dioxolanes give rise to some reduction products. Intramolecular allylation may be carried out via anchoring the triallylborane using an alkoxide anion. Mechanistic studies indicate that allyl transfer is from boron and not silicon, while stereoselectivity studies on the crotylation of acyclic acetals as well as the allylation of chiral acetals derived from (2R,4R)-pentanediol indicate moderate levels of diastereoselection.

  DOI：

  10.1016/s0040-4020(01)80802-4

文献信息

• Chemistry of organosilicon compounds. 191. Acetalization of carbonyl compounds with alkoxysilanes catalyzed by iodotrimethylsilane. One-pot allylation reactions of carbonyl compounds to homoallyl ethers using an allylsilane
  作者：Hideki Sakurai、Koshi Sasaki、Josaburo Hayashi、Akira Hosomi

  DOI：10.1021/jo00189a032

  日期：1984.7
• SAKURAI, HIDEKI;SASAKI, KOSHI;HAYASHI, JOSABURO;HOSOMI, AKIRA, J. ORG. CHEM., 1984, 49, N 15, 2808-2809
  作者：SAKURAI, HIDEKI、SASAKI, KOSHI、HAYASHI, JOSABURO、HOSOMI, AKIRA

  DOI：——

  日期：——