(2R,3S,4S)-4-(dimethylthexylsilyl)oxy-3-O-methoxymethyl-2,3-dihydroxy-2-methyl-5-cyclohexen-1-one | 514205-01-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4S)-4-(dimethylthexylsilyl)oxy-3-O-methoxymethyl-2,3-dihydroxy-2-methyl-5-cyclohexen-1-one
• CAS: 514205-01-7
• 化学式: C₁₇H₃₂O₅Si
• 分子量: 344.524
• InChiKey: YUHMNWYIYKWPAS-QRTARXTBSA-N

反应信息

• 作为反应物：
  描述：

  (2R,3S,4S)-4-(dimethylthexylsilyl)oxy-3-O-methoxymethyl-2,3-dihydroxy-2-methyl-5-cyclohexen-1-one 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 以52%的产率得到(2R,3S,4S)-2-methyl-3-O-methoxymethyl-2,3,4-trihydroxy-5-cyclohexen-1-one
  参考文献：
  名称：

  Chemoenzymatic synthesis of chiral enones from aromatic compounds

  摘要：

  A series of chiral enones was successfully synthesized from chemoenzymatically produced chiral diols. These chiral enones are highly functionalized synthons, which can be used in the total synthesis of natural products such as forskolin and avermectins. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(02)00682-1
• 作为产物：
  描述：

  (1S,2S,3S,4S)-4-(dimethylthexylsilyl)oxy-3-O-methoxymethyl-2-methyl-5-cyclohexen-1,2,3-triol 在 戴斯-马丁氧化剂 作用下， 以 二氯甲烷 为溶剂， 以80%的产率得到(2R,3S,4S)-4-(dimethylthexylsilyl)oxy-3-O-methoxymethyl-2,3-dihydroxy-2-methyl-5-cyclohexen-1-one
  参考文献：
  名称：

  Chemoenzymatic synthesis of chiral enones from aromatic compounds

  摘要：

  A series of chiral enones was successfully synthesized from chemoenzymatically produced chiral diols. These chiral enones are highly functionalized synthons, which can be used in the total synthesis of natural products such as forskolin and avermectins. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(02)00682-1