ethyl 3-(2',4'-dimethoxyphenyl)but-2-enoate | 7760-63-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: ethyl 3-(2',4'-dimethoxyphenyl)but-2-enoate
• 英文别名: 3-(2,4-dimethoxy-phenyl)-crotonic acid ethyl ester；3-(2,4-Dimethoxy-phenyl)-crotonsaeure-aethylester
• CAS: 7760-63-6
• 化学式: C₁₄H₁₈O₄
• 分子量: 250.295
• InChiKey: MSZHLSHBURTGIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.67
• 重原子数：
  18.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  44.76
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  溴乙酸乙酯 、 2,4-二甲氧基苯乙酮 在 锌 、 苯 作用下， 生成 ethyl 3-(2',4'-dimethoxyphenyl)but-2-enoate
  参考文献：
  名称：

  Herniation through both Winslow’s foramen and a lesser omental defect: Report of a case

  摘要：

  The herniation of small bowel through Winslow's foramen is a rare type of internal hernia which ran cause ileus; however, a hernia traversing the lesser sac is even more unusual. To the best of our knowledge, only 25 cases of herniation through Winslow's foramen and 10 cases of lesser sac hernia have been reported in the Japanese literature. We describe herein the case of a 33-year-old man who presented to our hospital complaining of abdominal pain in whom a plain abdominal radiograph revealed small bowel gas with air-fluid levels, suggesting ileus. Following admission, an ileus tube was inserted, but the intestinal shadow did not improve and surgery was performed based on suspicion of an internal hernia. Approximately 100 cm of ileum was found to have herniated through a defect in the lesser omentum after passing through Winslow's foramen, Since the herniated bowel was viable, manual reduction without resection was performed. The patient had a satisfactory postoperative course, and was discharged on postoperative day 11, There are many unknown aspects surrounding the etiology of Winslow's foramen hernia and lesser sac hernia, and although internal hernia is a rare cause of ileus, its possibility should be kept in mind.

  DOI：

  10.1007/s005950070125

文献信息

• Gunnewegh; Hoefnagel; Downing, Recueil des Travaux Chimiques des Pays-Bas, 1996, vol. 115, # 4, p. 226 - 230
  作者：Gunnewegh、Hoefnagel、Downing、Van Bekkum

  DOI：——

  日期：——