| 1258723-47-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• CAS: 1258723-47-5
• 化学式: C₁₉H₂₅NO
• 分子量: 283.414
• InChiKey: MOEFDOPAMWNNCS-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2-ethyl-1-oxo-4,4a,5,6-tetrahydro-1H-pyrido[1,2-a]quinolin-3-yl trifluoromethanesulfonate 在 正丁基锂 作用下， 以 甲苯 为溶剂， 以73%的产率得到
  参考文献：
  名称：

  Synthesis of (−)-(R)-angustureine by formal alkynylation of a chiral β-amino ester

  摘要：

  A new synthesis of (-)-angustureine is described, featuring an annulation and fragmentation sequence that formally results in alkynylation of a beta-amino ester. The six-step sequence from a readily available chiral beta-amino ester to the natural product was achieved in 46% yield, with no protecting groups and three purifications. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.12.122