Bis(3-oxohexyl)phosphinic acid | 140399-76-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Bis(3-oxohexyl)phosphinic acid
• 英文别名: bis(3-oxohexyl)phosphinic acid
• CAS: 140399-76-4
• 化学式: C₁₂H₂₃O₄P
• 分子量: 262.286
• InChiKey: RIGZXKIHRFPLDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-己酮 生成 Bis(3-oxohexyl)phosphinic acid
  参考文献：
  名称：

  Synthesis of γ-keto-substituted phosphinic acids from bis(trimethylsilyl)phosphonite and α,β-unsaturated ketones

  摘要：

  Mono- and di-substituted phosphinic acids have been synthesised in high yield by addition of silyl phosphonites to alpha,beta-unsaturated ketones, and conveniently purified via their adamantanammonium salts.

  DOI：

  10.1016/s0040-4039(00)77722-7

文献信息

• Synthesis of γ-keto-substituted phosphinic acids from bis(trimethylsilyl)phosphonite and α,β-unsaturated ketones
  作者：E. Andrew Boyd、Andrew C. Regan、Keith James

  DOI：10.1016/s0040-4039(00)77722-7

  日期：1992.2

  Mono- and di-substituted phosphinic acids have been synthesised in high yield by addition of silyl phosphonites to alpha,beta-unsaturated ketones, and conveniently purified via their adamantanammonium salts.