allyl(2-ethoxyvinyl)dimorpholin-4-ylphosphonium bromide | 1315511-28-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: allyl(2-ethoxyvinyl)dimorpholin-4-ylphosphonium bromide
• 英文别名: 2-ethoxyethenyl-dimethyl-prop-2-enylphosphanium;bromide
• CAS: 1315511-28-4
• 化学式: Br*C₉H₁₈OP
• 分子量: 253.119
• InChiKey: JQGIRQGJJXTLOP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.04
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  allyl(2-ethoxyvinyl)dimorpholin-4-ylphosphonium bromide 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 以44.5%的产率得到1,1-Dimethyl-λ⁵-phosphorin
  参考文献：
  名称：

  Electrocyclization of Phosphahexatrienes: An Approach to λ⁵-Phosphinines

  摘要：

  We experimentally verified an assumption that the substitution of a carbon atom with a pentavalent phosphorus atom in 1-alkoxy (dialkylamino) hexatrienes will not hamper its ability to electrocyclize. A series of 1-, 3-, and 5-phosphahexatrienes were synthesized. It was shown that parent lambda(5)-phosphinines could be synthesized by electrocyclization of the 3- and 5-phosphahexatrienes. The resultant electrocyclization is a convenient method for the synthesis of parent lambda(5)-phosphinines bearing different substituents on the phosphorus atom.

  DOI：

  10.1021/jo200847r
• 作为产物：
  描述：

  (2-ethoxyvinyl)(dimethyl)phosphine 、 3-溴丙烯 以 二氯甲烷 为溶剂， 反应 3.0h， 以85.5%的产率得到allyl(2-ethoxyvinyl)dimorpholin-4-ylphosphonium bromide
  参考文献：
  名称：

  Electrocyclization of Phosphahexatrienes: An Approach to λ⁵-Phosphinines

  摘要：

  We experimentally verified an assumption that the substitution of a carbon atom with a pentavalent phosphorus atom in 1-alkoxy (dialkylamino) hexatrienes will not hamper its ability to electrocyclize. A series of 1-, 3-, and 5-phosphahexatrienes were synthesized. It was shown that parent lambda(5)-phosphinines could be synthesized by electrocyclization of the 3- and 5-phosphahexatrienes. The resultant electrocyclization is a convenient method for the synthesis of parent lambda(5)-phosphinines bearing different substituents on the phosphorus atom.

  DOI：

  10.1021/jo200847r