4-(3-fluoro-4-trifluoromethoxyphenyl)cyclohexanone | 207462-85-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-(3-fluoro-4-trifluoromethoxyphenyl)cyclohexanone
• 英文别名: 4-[3-fluoro-4-(trifluoromethoxy)phenyl]cyclohexan-1-one
• CAS: 207462-85-9
• 化学式: C₁₃H₁₂F₄O₂
• 分子量: 276.231
• InChiKey: CKXXJHRJRXADGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-(3-fluoro-4-trifluoromethoxyphenyl)cyclohexanone 在 甲酸 、 potassium tert-butylate 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 21.0h， 生成 4-(3-Fluoro-4-trifluoromethoxy-phenyl)-cyclohexanecarbaldehyde
  参考文献：
  名称：

  Nematic Liquid Crystals with a Tetrafluoroethylene Bridge in the Mesogenic Core Structure

  摘要：

  A dramatic increase of the clearing temperatures of liquid crystals based on bis(cyclohcxyl)ethane 1 by 50 to 70 K can be achieved by the perfluorination of the central ethylene link. Conformational analysis indicates that this effect is due to the increased rigidity of the mesogenic core structure and to the suppression of conformers with a bent shape. Materials based on bis(cylohexyl)tetrafluoroethane 2 might play a crucial role as materials for the next generation of active matrix LCDs with reduced power consumption.

  DOI：

  10.1021/ja010024l
• 作为产物：
  描述：

  、 1-溴-3-氟-4-(三氟甲氧基)苯 4-溴-α,α,α-2-三氟苯甲醚 、 镁 、 1,2-环己二酮环乙缩醛 、 盐酸 在 乙醚 、 水 、 碳酸氢钠 、 magnesium sulfate 、 对甲苯磺酸 、 甲苯 、 silica gel 、 ethyl acetate heptane 、 甲酸 作用下， 以 四氢呋喃 为溶剂， 反应 9.0h， 以to obtain 4-(3-fluoro-4-trifluoromethoxyphenyl)cyclohexanone 22.0 g (84.5 mmol)的产率得到4-(3-fluoro-4-trifluoromethoxyphenyl)cyclohexanone
  参考文献：
  名称：

  Dioxane derivatives, liquid-crystal compositions containing the same, and liquid-crystal display devices made by using the same

  摘要：

  本发明提供了具有高电压保持比和显著高&Dgr;&egr;值、电化学稳定性以及与已知液晶化合物良好相容性的液晶化合物，包含该化合物的液晶组合物以及使用该化合物构成的液晶显示装置。本发明的液晶化合物是一种特定的二噁烷衍生物，由通式（1）表示。此外，本发明涉及到液晶组合物的特征在于组合物至少包括该衍生物之一，以及使用该组合物构成的液晶显示装置。

  公开号：

  US06235355B1

文献信息

• Dioxane derivatives, liquid-crystal compositions containing the same, and liquid-crystal display devices made by using the same
  申请人：Chisso Corporation

  公开号：US06235355B1

  公开（公告）日：2001-05-22

  The present invention provides liquid crystalline compounds having a high voltage holding ratio and a remarkably high &Dgr;&egr; value, electric and chemical stability, and having good compatibility with known liquid crystalline compounds, liquid crystal compositions containing the compound, and liquid crystal display devices constituted by using the compounds. The liquid crystalline compounds of the present invention are particular dioxane derivatives represented by general formula (1). Further, the present invention relates to liquid crystal compositions characterized in that the compositions comprise at least one of the derivatives, and liquid crystal display devices constituted by using the compositions.

  本发明提供了具有高电压保持比和显着高Δε值、电学稳定性和化学稳定性的液晶化合物，该化合物与已知的液晶化合物具有良好的相容性，包含该化合物的液晶组合物，以及通过使用该化合物构成的液晶显示装置。本发明的液晶化合物是特定的二氧杂环己烷衍生物，表示为通式（1）。此外，本发明涉及具有以下特征的液晶组合物，即该组合物至少包括上述衍生物之一，并且通过使用该组合物构成的液晶显示装置。
• Diene derivative
  申请人：Chisso Corporation

  公开号：US05609791A1

  公开（公告）日：1997-03-11

  A novel liquid crystal material having a carbon chain containing a conjugated diene as a terminal substituent of the molecule and exhibiting superior characteristics is provided, which is a diene derivative expressed by the formula (I) ##STR1## wherein R and R' each independently represent 1-5C alkyl; A and B each independently represent 1,4-cyclohexylene or 1,4-phenylene; n is 0 or 1; m is an integer of 0 to 2; X and X' each independently represent H atom or F atom when A is 1,4-phenylene or represent H atom when A is 1,4-cyclohexylene; Y is alkyl, halogen or CN, alkoxy, methyl group substituted by 1-3 halogen atoms or trihaloalkoxy when A is 1,4-phenylene, or represent alkyl, alkoxy, methyl group substituted by 1-3 halogen atoms or trihaloalkoxy when A is 1,4-cyclohexylene; and R and R' are not simultaneously alkyl chain of 4 or more carbon atoms. The compound of the present invention has a generally usable viscosity and a high NI point and a high elastic constant ratio; hence the liquid crystal composition, particularly the liquid crystal composition for STN, containing the compound of the present invention exhibits improved characteristics as compared with the conventional ones.

  本发明提供了一种具有碳链的新型液晶材料，其末端取代基包含共轭二烯，并表现出优越的特性，该二烯衍生物由式(I)表示， 其中R和R'分别独立表示1-5C烷基；A和B分别独立表示1,4-环己基或1,4-苯基；n为0或1；m为0到2的整数；X和X'分别表示H原子或F原子，当A为1,4-苯基时，或表示H原子，当A为1,4-环己基时；Y为烷基、卤素或CN、烷氧基、被1-3个卤原子取代的甲基基团或三卤代烷氧基，当A为1,4-苯基时，或表示烷基、烷氧基、被1-3个卤原子取代的甲基基团或三卤代烷氧基，当A为1,4-环己基时；且R和R'不同时为4个或更多碳原子的烷基链。 本发明的化合物具有通常可用的粘度、高NI点和高弹性常数比，因此，包含本发明化合物的液晶组合物，特别是STN的液晶组合物，与传统的液晶组合物相比，表现出改善的特性。
• Polycyclic diene derivatives
  申请人：Chisso Corporation

  公开号：EP0563982A2

  公开（公告）日：1993-10-06

  A novel liquid crystal material having a carbon chain containing a conjugated diene as a terminal substituent of the molecule and exhibiting superior characteristics is provided, which is a diene derivative expressed by the formula (I) wherein R and R' each independently represent 1-5C alkyl; A and B each independently represent 1,4-cyclohexylene or 1,4-phenylene; n is 0 or 1; m is an integer of 0 to 2; X and X' each independently represent H atom or F atom when A is 1,4-phenylene or represent H atom when A is 1,4-cyclohexylene; Y is alkyl, halogen or CN, alkoxy, methyl group substituted by 1-3 halogen atoms or trihaloalkoxy when A is 1,4-phenylene, or represent alkyl, alkoxy, methyl group substituted by 1-3 halogen atoms or trihaloalkoxy when A is 1,4-cyclohexylene; and R and R' are not simultaneously alkyl chain of 4 or more carbon atoms. The compound of the present invention has a generally usable viscosity and a high NI point and a high elastic constant ratio; hence the liquid crystal composition, particularly the liquid crystal composition for STN, containing the compound of the present invention exhibits improved characteristics as compared with the conventional ones.

  本发明提供了一种新型液晶材料，其碳链含有共轭二烯作为分子的末端取代基，具有优异的特性，它是由式 (I) 表示的二烯衍生物 其中 R 和 R'各自独立地代表 1-5C 烷基；A 和 B 各自独立地代表 1，4-环己烯或 1，4-亚苯基；n 为 0 或 1；m 为 0 至 2 的整数；X 和 X'各自独立地代表 H 原子或 F 原子（当 A 为 1，4-亚苯基时）或代表 H 原子（当 A 为 1，4-环己烯时）；Y是烷基、卤素或CN、烷氧基、被1-3个卤素原子或三卤代烷氧基取代的甲基（当A为1,4-亚苯基时），或代表烷基、烷氧基、被1-3个卤素原子或三卤代烷氧基取代的甲基（当A为1,4-环己烯时）；且R和R'不同时是4个或更多碳原子的烷基链。 本发明的化合物具有一般可用的粘度、高 NI 点和高弹性常数比；因此，与传统的液晶组合物相比，含有本发明化合物的液晶组合物，特别是 STN 用液晶组合物，具有更好的特性。
• DIOXANE DERIVATIVES, LIQUID-CRYSTAL COMPOSITIONS CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY DEVICES MADE BY USING THE SAME
  申请人：CHISSO CORPORATION

  公开号：EP0881221A1

  公开（公告）日：1998-12-02

  The present invention provides liquid crystalline compounds having a high voltage holding ratio and a remarkably high Δ ε value, electric and chemical stability, and having good compatibility with known liquid crystalline compounds, liquid crystal compositions containing the compound, and liquid crystal display devices constituted by using the compounds. The liquid crystalline compounds of the present invention are particular dioxane derivatives represented by general formula (1). Further, the present invention relates to liquid crystal compositions characterized in that the compositions comprise at least one of the derivatives, and liquid crystal display devices constituted by using the compositions.

  本发明提供的液晶化合物具有较高的电压保持率和显着较高的Δ ε 值、电气和化学稳定性，并且与已知液晶化合物、含有该化合物的液晶组合物和使用该化合物构成的液晶显示设备具有良好的兼容性。 本发明的液晶化合物是由通式（1）表示的特定二恶烷衍生物。此外，本发明还涉及液晶组合物，其特征在于该组合物包含至少一种衍生物，以及使用该组合物构成的液晶显示装置。
• US5449810A
  申请人：——

  公开号：US5449810A

  公开（公告）日：1995-09-12