9-chloro-8-fluoro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid | 848085-70-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 9-chloro-8-fluoro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
• CAS: 848085-70-1
• 化学式: C₁₃H₁₁ClFNO₂
• 分子量: 267.687
• InChiKey: QSFYZRFEBQWXJB-UHFFFAOYSA-N

物化性质

• 沸点：
  397.8±42.0 °C(Predicted)
• 密度：
  1.422±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS
  申请人：FRECHETTE Roger

  公开号：US20090203726A1

  公开（公告）日：2009-08-13

  A method of treating a subject for a bacterial infection includes administering to a subject in need of treatment for a bacterial infection an effective amount of a compound represented by structural formula (I-a), or a pharmaceutically acceptable salt, solvate, or hydrate thereof. The variables in structural formula (I-a) are described herein.
• [EN] SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS<br/>[FR] TÉTRAHYDROQUINOLINES SUBSTITUÉES UTILISÉES EN TANT QU'AGENTS ANTIBACTÉRIENS
  申请人：MAXTHERA INC

  公开号：WO2009073550A2

  公开（公告）日：2009-06-11

  A method of treating a subject for a bacterial infection includes administering to a subject in need of treatment for a bacterial infection an effective amount of a compound represented by structural formula (I-a), or a pharmaceutically acceptable salt, solvate, or hydrate thereof. The variables in structural formula (I-a) are described herein.