6-O-acetylgalactose | 104112-61-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-O-acetylgalactose
• 英文别名: [(2R,3R,4S,5R,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl acetate
• CAS: 104112-61-0
• 化学式: C₈H₁₄O₇
• 分子量: 222.195
• InChiKey: ILLOJQCWUBEHBA-HNEXDWKRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  D-吡喃葡萄糖 、 2,2,2-三氯乙酸乙酯 在 porcine pancreatic lipase 吡啶 作用下， 反应 48.0h， 以60%的产率得到6-O-acetylgalactose
  参考文献：
  名称：

  Facile enzymatic preparation of monoacylated sugars in pyridine

  摘要：

  DOI：

  10.1021/ja00278a053

文献信息

• Verfahren zur beta-Galactosidase-katalysierten Transglycosidierung mit unphysiologischen Glycosyldonoren
  申请人：HOECHST AKTIENGESELLSCHAFT

  公开号：EP0551107A2

  公开（公告）日：1993-07-14

  Die Erfindung betrifft Verfahren zur β-Galactosidase-katalysierten Transglycosidierung, wobei als Glycosyldonoren für β-Galactosidase unphysiologische bzw. unnatürliche Glycoside eingesetzt werden.

  本发明涉及β-半乳糖苷酶催化的转糖苷化过程，其中使用非生理或非天然糖苷作为β-半乳糖苷酶的糖基供体。
• AN IMPROVED PROCESS FOR PRODUCING CHLORINATED SUCROSE
  申请人：Pharmed Medicare Private Limited

  公开号：EP1735327A1

  公开（公告）日：2006-12-27
• [EN] AN IMPROVED PROCESS FOR PRODUCING CHLORINATED SUCROSE<br/>[FR] PROCEDE AMELIORE POUR LA PRODUCTION DE SACCHAROSE CHLORE
  申请人：PHARMED MEDICARE PVT LTD

  公开号：WO2005090374A1

  公开（公告）日：2005-09-29

  Present invention relates to disclosure of application of some innovative techniques useful for substantially improving process efficiency of production of chlorinated sucrose including their intermediates and derivatives. Application of mild methods of drying has been made for recovery of chlorinated sucrose or their intermediates and derivatives, in substantially pure form or with other solid chemical impurities, obtained at various stages in the process of production of chlorinated sucrose. Mild methods of drying included agitated thin film drying, spray drying, freeze drying and super critical extraction. Use of alkoxides has been introduced for deacylation instead of alkali hydroxides or alkaline earth hydroxides. Deacylation has been shown to be effective both, either before or after drying of the reaction mixture. Extraction and purification of desired products i.e. of chlorinated sucrose or its intermediates or derivatives, from dried solid mixtures could be achieved by using appropriate extraction method, including but not limited to solvent extraction and super critical extraction. Further purification of such extracts can be done by crystallization or direct drying under mild conditions.