1-(ferrocenylcarbonyl)-1H-benzotriazole | 1163726-65-5

• 英文名称: 1-(ferrocenylcarbonyl)-1H-benzotriazole
• 英文别名: (1H-benzotriazol-1-ylcarbonyl)ferrocene；[FcCOBt]
• CAS: 1163726-65-5
• 化学式: C₁₇H₁₃FeN₃O
• 分子量: 331.157
• InChiKey: ZDDCKGAKYPVQEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  1,5-二氨基-2-甲基戊烷 、 1-(ferrocenylcarbonyl)-1H-benzotriazole 以 氯仿 为溶剂， 以62%的产率得到
  参考文献：
  名称：

  Microwave assisted synthesis of ferrocene amides

  摘要：

  A new microwave assisted synthesis methodology has been presented for the preparation of the ferrocene amides. Ferrocene carboxylic acid was derivatised using direct 1H-Benzotriazole/SOCl2 methodolgy to prepare N-ferrocenoyl benzotriazole as a new starting material for the functionalization of ferrocene ring. N-ferrocenoyl benzotriazole was reacted with mono- and di-amines under microwave irradiation to prepare ferrocene mono- and di-amides in high purity and in good yield. (C) 2008 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2008.05.023
• 作为产物：
  描述：

  二茂铁甲酸 、 1-(甲磺酰基)-1H-苯并三唑 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 以76%的产率得到1-(ferrocenylcarbonyl)-1H-benzotriazole
  参考文献：
  名称：

  Pd（ii）配合物中的多供体膦基二茂铁羧酰胺配体的多功能配位和CH活化†

  摘要：

  制备了多供体膦基二茂铁羧酰胺FcCONHCH 2 CH 2 PPh 2（1，Fc =二茂铁基），将其转化为相应的氧化膦1O和硒化膦1Se，并且主要作为Pd（II）配合物中的配体进行了研究。在其天然形式，酰胺1优先协调软的Pd（II），其为简单的膦，产生的混合物的顺式和反式- [PDX 2（1个-κ P）2 ]（2 ; X = Cl（上一个），溴（b），和I（Ç）），其中所述异构体比例依赖于辅助配体的卤化物，或者，到络合物[（L NC）的PdCl（1个-κ P）]（6，L NC = 2 - [（二甲基氨基）甲基κ ñ ]苯基-κ ç 1）。但是，在钯上创建一个空位的协作位点时，这种协作模式很容易改变。因此，治疗的图2a用NH 4 [PF 6 ]中游离存在1制备[的PdCl（1个-κ P）3 ] [PF 6 ]（3），而完全去除卤素与银（我导致阳离子络合物）盐顺式- [钯（1 -κ 2 ö，P）2

  DOI：

  10.1039/c9dt03646f

文献信息

• N-ferrocenoyl benzotriazole: A convenient tool for the synthesis of ferrocenoyl esters
  作者：Deniz Hür、Sultan Funda Ekti、Hakan Dal

  DOI：10.1016/j.jorganchem.2009.11.015

  日期：2010.4

  A new synthesis methodology has been presented for the preparation of the ferrocenoyl esters. Ferrocene carboxylic acid was derivatized using direct 1H-benzotriazole/SOCl2 methodology to prepare N-ferrocenoyl benzotriazole as a convenient tool for the functionalization of ferrocene ring. N-ferrocenoyl benzotriazole was reacted with alcohols in mild conditions to prepare ferrocenoyl esters in high purity and in good yield. The solid state structure of benzyl-1-ferrocenoate, 2f, has also been determined by X-ray crystallography. In the crystal structure, intermolecular C-H center dot center dot center dot O hydrogen bonds link the molecules into a two-dimensional network. The pi center dot center dot center dot pi contacts between the cyclopentadiene rings and cyclopentadiene and phenyl rings, [centroid-centroid distances = 3.296(1) and 3.750(1) angstrom] may further stabilize the structure. Two weak C-H center dot center dot center dot pi interactions are also found. (C) 2009 Elsevier B. V. All rights reserved.
• N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids
  作者：Deniz Hür、Sultan Funda Ekti Dal、Görkem Ali Varol、Evrim Hür

  DOI：10.1016/j.jorganchem.2011.03.037

  日期：2011.7

  In this study, crystalline and chirally stable carboxyl-protected and novel unprotected N-ferrocenoyl amino acid derivatives of Ser, Cys, Ala, Phe, Trp, Asp and Asn have been prepared. These amino acids undergo substitution reaction with 1-(ferrocenylcarbonyl)-1H-benzotriazole, 1, in partially aqueous media under microwave irradiation. (C) 2011 Elsevier B.V. All rights reserved.