maltosyl(α1->6)γ-cyclodextrin | 104723-64-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: maltosyl(α1->6)γ-cyclodextrin
• 英文别名: 6-O-α-D-maltosyl-γ-cyclodextrin；maltosyl-γ-CD；maltosyl-γCD；(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,38R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-20-[[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]-5,10,15,25,30,35,40-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol
• CAS: 104723-64-0
• 化学式: C₆₀H₁₀₀O₅₀
• 分子量: 1621.42
• InChiKey: UHNMCSZNLJSICD-MYWUTMGMSA-N

物化性质

• 密度：
  1.90±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -21.76
• 重原子数：
  110.0
• 可旋转键数：
  14.0
• 环数：
  32.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  791.5
• 氢给体数：
  30.0
• 氢受体数：
  50.0

反应信息

• 作为反应物：
  描述：

  maltosyl(α1->6)γ-cyclodextrin 反应 1.0h， 以8%的产率得到
  参考文献：
  名称：

  Preparation, isolation, and characterization of novel heterogeneous branched cyclomalto-oligosaccharides having β-d-galactosyl residue(s) on the side chain

  摘要：

  Transgalactosylated products of branched cyclodextrins (glucosyl-alphaCD, -betaCD, -gammaCD, and maltosyl-alphaCD, -betaCD, -gammaCD)were synthesized by beta-D-galactosidases from Bacillus circulans and Penicillium multicolor using lactose as a donor substrate and branched CDs as acceptors. Eighteen beta-D-galactosylated branched CDs were isolated and purified by HPLC. Their structures were elucidated by FABMS and C-13 NMR spectroscopies, and methylation analysis. The chromatographic behavior of these novel heterogeneous branched CDs on three HPLC columns of different separation modes was compared.

  DOI：

  10.1016/0008-6215(93)87006-e
• 作为产物：
  描述：

  麦芽糖 、 γ-环糊精 反应 60.0h， 以2.5 g的产率得到maltosyl(α1->6)γ-cyclodextrin
  参考文献：
  名称：

  Shiraishi, Takanori; Kusano, Shuichi; Tsumuraya, Yoichi, Agricultural and Biological Chemistry, 1989, vol. 53, # 8, p. 2181 - 2188

  摘要：

  DOI：

文献信息

• Synthesis of branched cyclomaltooligosaccharide carboxylic acids (cyclodextrin carboxylic acids) by microbial oxidation
  作者：Toshihiro Ishiguro、Takako Fuse、Masahide Oka、Takashi Kurasawa、Masanari Nakamichi、Yoshihiro Yasumura、Masahiko Tsuda、Takamasa Yamaguchi、Ikuo Nogami

  DOI：10.1016/s0008-6215(01)00053-2

  日期：2001.4

  (cyclodextrin carboxylic acid) derivatives were synthesized by microbial oxidation using Pseudogluconobacter saccharoketogenes to oxidize five types of branched cyclodextrins, including maltosyl beta-cyclodextrin (maltosyl-beta-CyD). For each novel cyclodextrin carboxylic acid derivative synthesized, the hydroxymethyl group of the terminal glucose residue in the branched part of the molecule was regiospecifically

  新型的支链环麦芽低聚糖羧酸衍生物（环糊精羧酸）衍生物是利用假葡糖杆菌糖原基因通过微生物氧化合成的，可氧化五种类型的支链环糊精，包括麦芽糖基β-环糊精（麦芽糖基-β-CyD）。对于每种合成的新型环糊精羧酸衍生物，将分子支链部分中末端葡萄糖残基的羟甲基区域特异性地氧化为羧基，得到相应的糖醛酸。此外，环麦芽庚糖基-（6-> 1）-α-D-吡喃葡萄糖基-（4-> 1）-α-D-吡喃葡糖醛糖醛酸（GUG-β-CyD）（1）及其钠的理化性质由于这些化合物最有可能实际应用，因此对其进行了更广泛的研究。
• OKADA, YASUYO;KUBOTA, YOKO;KOIZUMI, KYOKO;HIZUKURI, SUSUMU;OHFUJI, TAKEHI+, CHEM. AND PHARM. BULL., 36,(1988) N 6, C. 2176-2185
  作者：OKADA, YASUYO、KUBOTA, YOKO、KOIZUMI, KYOKO、HIZUKURI, SUSUMU、OHFUJI, TAKEHI+

  DOI：——

  日期：——