triethyl iodoorthoacetate | 183115-34-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: triethyl iodoorthoacetate
• 英文别名: triethoxyethyliodide；iodo-orthoacetic acid triethyl ester；Jod-orthoessigsaeure-triaethylester；1,1,1-Triethoxy-2-iodoethane
• CAS: 183115-34-6
• 化学式: C₈H₁₇IO₃
• 分子量: 288.126
• InChiKey: HPUKTMULHXQTFC-UHFFFAOYSA-N

物化性质

• 沸点：
  96-98 °C(Press: 10 Torr)
• 密度：
  1.4200 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  triethyl iodoorthoacetate 、 锌 以 乙醚 为溶剂， 生成
  参考文献：
  名称：

  The Ethyl Orthohalogenoacetates and their Reaction with Zinc and Magnesium

  摘要：

  DOI：

  10.1021/ja01286a033
• 作为产物：
  描述：

  原乙酸三乙酯 在 吡啶 、 乙醇 、 溴 、 sodium iodide 作用下， 生成 triethyl iodoorthoacetate
  参考文献：
  名称：

  Beyerstedt; McElvain, Journal of the American Chemical Society, 1937, vol. 59, p. 1274

  摘要：

  DOI：

文献信息

• 3′,5′-O-Phosphonoalkylidene derivatives of 1-(2-deoxy-β-D-threo-pentofuranosyl)thymine: Synthesis and reactivity
  作者：Magdalena Endová、Milena Masojídková、Miloš Buděšínský、Ivan Rosenberg

  DOI：10.1016/s0040-4020(98)00654-1

  日期：1998.9

  Various 3′,5′-O-(1-phosphonoalkylidene) derivatives of 1-(2-deoxy-β-D-threo-pentofuranosyl)thymine bearing a substituent in the ω-position of the alkylidene chain were prepared by the redox reaction of diethyl chlorophosphite with six-membered 3′,5′-orthoesters of xylo-dT. Susceptibility of ω-haloalkylidene derivatives for nucleophilic substitution is discussed. The configuration of the final phosphonates

  通过氧化还原反应制备了在亚烷基链的ω-位置带有取代基的1-（2-脱氧-β-D-苏-五氟呋喃糖基）胸腺嘧啶的各种3'，5'-O-（1-膦酰基亚烷基）衍生物氯亚磷酸二乙酯与木糖-dT的六元3'，5'-原酸酯。讨论了ω-卤代亚烷基衍生物对亲核取代的敏感性。最终膦酸酯的构型通过2D-ROESY NMR实验确定。
• Nef, Justus Liebigs Annalen der Chemie, 1897, vol. 298, p. 322
  作者：Nef

  DOI：——

  日期：——
• Regioselective Synthesis of 1,4-Di(organo)[60]fullerenes through DMF-assisted Monoaddition of Silylmethyl Grignard Reagents and Subsequent Alkylation Reaction
  作者：Yutaka Matsuo、Akihiko Iwashita、Yoko Abe、Chang-Zhi Li、Keiko Matsuo、Masahiko Hashiguchi、Eiichi Nakamura

  DOI：10.1021/ja8041299

  日期：2008.11.19

  Monoaddition of Grignard reagents, in particular tri(organo)silylmethyl magnesium chlorides, to [60]fullerene took place smoothly in the presence of dimethylformamideto produce (organo)(hydro)[60]fullerenes, (C60RH)-H-1, in good yield (up to 93% isolated yield). The hydrofullerene was then deprotonated to generate the corresponding anion, C60R-, which was then alkylated to obtain 58 pi-electron di(organo)[60]fullerenes, (C60RR2)-R-1, in good to high yield (up to 93% overall yield). The two-step methodology provides a wide variety of 1,4-di(organo)[60] fullerenes bearing the same or different organic addends on the [60] fullerene core. By changing the addends, one can control the chemical and physical properties of the compounds at the molecular and bulk levels.
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Zn: SVol., 194, page 600 - 602
  作者：

  DOI：——

  日期：——
• Endova, Magdalena; Masojidkova, Milena; Rosenberg, Ivan, Collection of Czechoslovak Chemical Communications, 1996, vol. 61, p. S167 - S170
  作者：Endova, Magdalena、Masojidkova, Milena、Rosenberg, Ivan

  DOI：——

  日期：——