3-α-glucosyl α,α-trehalose | 832700-09-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-α-glucosyl α,α-trehalose
• 英文别名: Glc(a1-3)Glc(a1-1a)Glc；(2R,3R,4S,5S,6R)-2-[(2R,3R,4S,5R,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 832700-09-1
• 化学式: C₁₈H₃₂O₁₆
• 分子量: 504.442
• InChiKey: VBMQKUDEYKVQNV-FFOXLREASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.8
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  269
• 氢给体数：
  11
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  Lactose 、 3-α-glucosyl α,α-trehalose 在 BIOLACTA 作用下， 反应 48.17h， 以22.7%的产率得到葡萄糖
  参考文献：
  名称：

  3-Alpha-glycosyl alpha, alpha-trehalose compound, process for producing the same, and use

  摘要：

  本发明的一个目的是提供一种新型的糖类，即分子中具有由化学式1表示的3-α-葡萄糖基α,α-海藻糖结构的3-α-葡萄糖基α,α-海藻糖，以及它们的制备和用途。本发明通过提供分子中具有由化学式1表示的3-α-葡萄糖基α,α-海藻糖结构的3-α-葡萄糖基α,α-海藻糖，以及它们的制备和用途来实现上述目的。O-α-D-Glcp-(1→3)-O-α-D-Glcp-(1→1)-α-D-Glcp 化学式1

  公开号：

  US20060183714A1
• 作为产物：
  描述：

  3-α-isomaltosyl α,α-trehalose 在 GLYCOZYME#12000 作用下， 反应 24.17h， 以71.7%的产率得到3-α-glucosyl α,α-trehalose
  参考文献：
  名称：

  3-Alpha-glycosyl alpha, alpha-trehalose compound, process for producing the same, and use

  摘要：

  本发明的一个目的是提供一种新型的糖类，即分子中具有由化学式1表示的3-α-葡萄糖基α,α-海藻糖结构的3-α-葡萄糖基α,α-海藻糖，以及它们的制备和用途。本发明通过提供分子中具有由化学式1表示的3-α-葡萄糖基α,α-海藻糖结构的3-α-葡萄糖基α,α-海藻糖，以及它们的制备和用途来实现上述目的。O-α-D-Glcp-(1→3)-O-α-D-Glcp-(1→1)-α-D-Glcp 化学式1

  公开号：

  US20060183714A1

文献信息

• Non-reducing oligosaccharides and their production and use
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0636632A2

  公开（公告）日：1995-02-01

  Novel non-reducing oligosaccharide having a structure represented by the formula of alpha-D-oligoglucosyl alpha-D-oligoglucoside is obtained by exposing either an aqueous solution which contains trehalose and an alpha-glucosyl saccharide or an aqueous solution which contains a non-reducing saccharide bearing a trehalose structure at its end to a saccharide-transferring enzyme. The oligosaccharide has a reduced sweetness, superior stability, appropriate viscosity and less or no susceptibility to crystallization or superior solubility when in crystalline form. These features make the oligosaccharide very useful in various compositions including foods, beverages, cosmetics, pharmaceuticals and shaped bodies.

  新型非还原性寡糖的结构式为 alpha-D-oligoglucosyl alpha-D-oligoglucoside ，其获得方法是将含有脱卤糖和α-葡糖基糖的水溶液或含有末端带有脱卤糖结构的非还原性糖的水溶液与糖转移酶接触。这种低聚糖甜度低、稳定性好、粘度适中、不易结晶或结晶后溶解性好。这些特点使得低聚糖在食品、饮料、化妆品、药品和成型体等各种成分中非常有用。
• Trehalose releasing enzyme, DNA encoding therefor, their preparation and uses
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0671470A2

  公开（公告）日：1995-09-13

  Disclosed are a DNA encoding an enzyme which releases trehalose from non-reducing saccharides having a trehalose structure as an end unit and having a degree of glucose polymerization of 3 or higher, recombinant DNA and enzyme, transformant, and their preparations and uses. These facilitate the industrial-scale production of trehalose with a relative easiness and low cost, and trehalose thus obtained can be satisfactorily used in a variety of food products, cosmetics and pharmaceuticals.

  本发明公开了一种编码酶的 DNA、重组 DNA 和酶、转化体及其制备方法和用途，该酶可从以曲海洛糖结构为末端单位且葡萄糖聚合度为 3 或更高的非还原糖中释放出曲海洛糖。这些都有助于以相对容易和低成本的方式进行工业规模的脱糖糖生产，由此获得的脱糖糖可令人满意地用于各种食品、化妆品和药品中。
• Thermostable trehalose-releasing enzyme, and its preparation and uses
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0688866A1

  公开（公告）日：1995-12-27

  Disclosed is a thermostable trehalose-releasing enzyme, and its preparations and uses. The enzyme is obtainable from the culture of microorganisms such as Sulfolobus acidocaldarius (ATCC 33909 and ATCC 49426) and Sulfolobus solfataricus (ATCC 35091 and ATCC 35092), and capable of hydrolyzing at a temperature of over 55°C the linkage between a trehalose moiety and the remaining glycosyl moiety in a non-reducing saccharide having a trehalose structure as an end unit and having a degree of glucose polymerization of 3 or higher. Trehalose and compositions containing the same are extensively useful in food products, cosmetics and pharmaceuticals.

  本发明公开了一种可恒温释放脱卤糖的酶及其制剂和用途。该酶可从酸性硫球菌（Sulfolobus acidocaldarius）（ATCC 33909 和 ATCC 49426）和溶血硫球菌（Sulfolobus solfataricus）（ATCC 35091 和 ATCC 35092）等微生物的培养物中获得，能够在 55°C 以上的温度下水解以三卤糖苷结构为末端单位、葡萄糖聚合度为 3 或更高的非还原糖中的三卤糖苷分子和剩余糖基分子之间的连接。在食品、化妆品和药品中，妥尔糖和含有妥尔糖的组合物具有广泛的用途。
• Saccharide composition with reduced reducibility, and preparation and uses thereof
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0690130A1

  公开（公告）日：1996-01-03

  A saccharide composition with a reduced reducibility which is prepared by hydrogenating a saccharide mixture comprising reducing saccharides and non-reducing saccharides consisting of trehalose and/or saccharides having a trehalose structure. The saccharide composition has a satisfactory sweetness, taste and stability, and is substantially free from reducibility, so that it can be freely used in a variety of compositions such as foods, cosmetics and pharmaceuticals which are susceptible to reduction.

  一种还原性降低的糖组合物，它是通过氢化由还原性糖和非还原性糖组成的糖混合物制备的，还原性糖和非还原性糖由三卤糖和/或具有三卤糖结构的糖组成。这种糖组合物具有令人满意的甜味、口感和稳定性，而且基本上没有还原性，因此可以自由地用于各种组合物，如食品、化妆品和药品等易受还原性影响的组合物中。
• Recombinant thermostable enzyme which releases trehalose from non-reducing saccharide
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0697461A1

  公开（公告）日：1996-02-21

  Disclosed is a recombinant thermostable enzyme which has a molecular weight of about 54,000-64,000 daltons and a pI of about 5.6-6.6, and releases trehalose from non-reducing saccharides having a trehalose structure as an end unit and a degree of glucose polymerization of at least 3. The enzyme has a satisfactorily-high thermostability, i.e. it is not substantially inactivated even when incubated in an aqueous solution (pH 7.0) at 85°C for 60 min, and this facilitates the production of trehalose on an industrial scale and in a satisfactorily-high yield.

  本发明公开了一种重组恒温酶，其分子量约为 54,000-64,000 道尔顿，pI 约为 5.6-6.6，可从以三卤糖结构为末端单位且葡萄糖聚合度至少为 3 的非还原糖中释放出三卤糖。该酶具有令人满意的高热稳定性，即即使在 85°C 的水溶液（pH 值为 7.0）中孵育 60 分钟，该酶也不会基本失活，这有助于以令人满意的高产率在工业规模上生产脱盐海藻糖。