3-[4-(3-Amino-3-oxoprop-1-enyl)phenyl]prop-2-enamide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 3-[4-(3-Amino-3-oxoprop-1-enyl)phenyl]prop-2-enamide
• 化学式: C₁₂H₁₂N₂O₂
• 分子量: 216.24
• InChiKey: AFGDLMRJXDHYSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  86.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES<br/>[FR] COMPOSÉS À PETITES MOLÉCULES MIMÉTIQUES DES FACTEURS DE CROISSANCE HÉMATOPOÏÉTIQUE ET LEURS UTILISATIONS
  申请人：LIGAND PHARM INC

  公开号：WO2011046954A1

  公开（公告）日：2011-04-21

  The present embodiments relate to compounds with physiological effects, such as the activation of hematopoietic growth factor receptors. The present embodiments also relate to use of the compounds to treat a variety of conditions, diseases and ailments such as hematopoietic conditions and disorders.

  目前的实施例涉及具有生理效应的化合物，例如激活造血生长因子受体。目前的实施例还涉及利用这些化合物来治疗各种疾病、疾病和疾患，如造血状况和疾病。
• MOLECULARLY IMPRINTED POLYMERS FOR THE RECOGNITION OF GLUTATHIONE GSH, METHODS FOR PREPARING SAME AND USES THEREOF
  申请人：Perollier Celine

  公开号：US20100234565A1

  公开（公告）日：2010-09-16

  The present invention relates to new molecularly imprinted polymers which are suitable for the selective recognition of glutathione GSH and/or of an analog thereof, and in particular which are of use for the treatment of media comprising in particular a mixture of glutathione GSH, and/or of an analog thereof, with GSH adducts.

  本发明涉及新的分子印迹聚合物，适用于选择性识别谷胱甘肽GSH和/或其类似物，特别是用于处理包括谷胱甘肽GSH和/或其类似物与GSH加合物的介质。
• Molecular Fingerprints With Enhanced Identifying Capability, Method for Preparing Same and Use Thereof
  申请人：Bay-Oudh Sami

  公开号：US20090123411A1

  公开（公告）日：2009-05-14

  The invention concerns a method for preparing a molecular fingerprint comprising sites for identifying at least one target molecule, said fingerprint being obtained from at least one master molecule of polymeric type, called master polymer. The invention is characterized in that said master polymer is different from the target molecule(s), and is capable of being eliminated by degradation and/or washing, and that at least 5% in number of monomer units constituting the master polymer are involved in the formation of the sites for identifying the target molecule(s).

  本发明涉及一种制备分子指纹的方法，该指纹包括用于识别至少一种目标分子的位点，该指纹是从至少一种聚合型母体分子，称为母体聚合物中获得的。本发明的特点在于，所述母体聚合物与目标分子不同，并且能够通过降解和/或清洗被消除，而且构成用于识别目标分子的位点的单体单位中至少有5％参与其中。
• Method of preparing inorganic pigment dispersions
  申请人：HENKEL CORPORATION

  公开号：EP0872494A2

  公开（公告）日：1998-10-21

  A polymer useful as an inorganic pigment dispersant is provided. The polymer is derived by polymerization of monomers consisting essentially of an ethylenically unsaturated aromatic monomer, an ethylenically unsaturated dicarboxylic acid monomer, and an ethylenically unsaturated monocarboxylic acid monomer. The monomers are polymerized in the presence of a mercapto-functional compound. The total amount of said ethylenically unsaturated acid monomers is sufficient to permit said polymer to associate with an inorganic pigment in an aqueous medium in a manner which disperses said inorganic pigment in said aqueous medium to form a stable aqueous dispersion of said inorganic pigment, and the amount of said ethylenically unsaturated aromatic monomer is sufficient to reduce the water sensitivity of a dried coating of a latex paint comprised of said stable aqueous dispersion of said inorganic pigment. A process of preparing a polymer useful as an inorganic pigment dispersant and a method of preparing an inorganic pigment dispersion useful in the preparation of latex paints are also provided.

  提供了一种可用作无机颜料分散剂的聚合物。这种聚合物是通过聚合主要由乙烯不饱和芳香族单体、乙烯不饱和二羧酸单体和乙烯不饱和单羧酸单体组成的单体而得到的。这些单体在巯基官能化合物的存在下聚合。所述乙烯基不饱和酸单体的总量足以使所述聚合物与水性介质中的无机颜料以分散所述水性介质中的无机颜料的方式结合，形成所述无机颜料的稳定水性分散体，而所述乙烯基不饱和芳香族单体的量足以降低由所述无机颜料的稳定水性分散体组成的乳胶漆干燥涂层的水敏性。本发明还提供了一种可用作无机颜料分散剂的聚合物的制备方法和一种可用于制备乳胶漆的无机颜料分散体的制备方法。
• Curable jettable liquid for the production of a flexographic printing plate
  申请人：AGFA-GEVAERT

  公开号：EP1637926A2

  公开（公告）日：2006-03-22

  A curable jettable liquid for manufacturing a flexographic printing plate comprising at least one photo-initiator, at least one monofunctional monomer, at least 5 wt% of a polyfunctional monomer or oligomer and at least 5 wt% of a plasticizer both based on the total weight of the curable jettable liquid capable of realizing a layer after curing having an elongation at break of at least 5%, a storage modulus E' smaller than 200mPa at 30Hz and a volumetric shrinkage smaller than 10%.

  一种用于制造柔性版印刷板的固化型可浇注液体，包含至少一种光引发剂、至少一种单官能团单体、至少 5 wt%的多官能团单体或低聚物以及至少 5 wt%的增塑剂，二者均以固化型可浇注液体的总重量为基准，固化后可形成一层断裂伸长率至少为 5%、30 Hz 时储存模量 E' 小于 200mPa 且体积收缩率小于 10%的层。