3’,5,5’,7-tetrahydroxyflavanone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3’,5,5’,7-tetrahydroxyflavanone
• 英文别名: 5,7,3′,5′-tetrahydroxyflavanone；(±)-3',5',5,7-tetrahydroxyflavanone；7,3’,5’-trihydroxyflavanone；5,7,3',5'-tetrahydroxydihydroflavone；3',5',5,7-tetrahydroxyflavanone；3',5,5',7-tetrahydroxyflavanone；5,7,3',5'-Tetrahydroxyflavanone；2-(3,5-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
• 化学式: C₁₅H₁₂O₆
• 分子量: 288.257
• InChiKey: AYHOUUNTAVCXBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3,5-二羟基苯甲醇 在 氢氧化钾 、 磷酸 、 三氯化硼 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 5.0h， 生成 3’,5,5’,7-tetrahydroxyflavanone
  参考文献：
  名称：

  Huazhongilexone is not 3',5,5',7-Tetrahydroxyflavanone. Preparation of 3',5'-Dimethoxy-5,7-dihydroxyflavanone.

  摘要：

  Huazhongilexone, isolated from Ilex centrochinensis, was originally assigned the structure 3 ',5,5 ',7-tetrahydroxyflavanone. The racemic flavanone has been synthezised. Huazhongilexone is different from the synthetic compound and thus must have a different structure. In addition the new (+/-)-3 ',5 '-dimethoxy-5,7-dihydroxyflavanone has been prepared and characterized.

  DOI：

  10.3891/acta.chem.scand.52-1243

文献信息

• Chan, Wing Lai; Lin, Yong Cheng; Zhang, Wei Han, Heterocycles, 1996, vol. 43, # 3, p. 551 - 554
  作者：Chan, Wing Lai、Lin, Yong Cheng、Zhang, Wei Han、Tang, Pak Lai、Szeto, Yau Shan

  DOI：——

  日期：——
• Huazhongilexone is not 3',5,5',7-Tetrahydroxyflavanone. Preparation of 3',5'-Dimethoxy-5,7-dihydroxyflavanone.
  作者：Uffe Anthoni、Rosalba Encarnación D.、Per H. Nielsen、Carsten Christophersen、Inger Wahlberg、Luis Juliá、Ola Persson

  DOI：10.3891/acta.chem.scand.52-1243

  日期：——

  Huazhongilexone, isolated from Ilex centrochinensis, was originally assigned the structure 3 ',5,5 ',7-tetrahydroxyflavanone. The racemic flavanone has been synthezised. Huazhongilexone is different from the synthetic compound and thus must have a different structure. In addition the new (+/-)-3 ',5 '-dimethoxy-5,7-dihydroxyflavanone has been prepared and characterized.