[1-(3,4-Dimethoxyphenyl)-2-(3-phenylprop-2-enoylamino)ethyl] 3-phenylprop-2-enoate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: [1-(3,4-Dimethoxyphenyl)-2-(3-phenylprop-2-enoylamino)ethyl] 3-phenylprop-2-enoate
• 英文别名: [1-(3,4-dimethoxyphenyl)-2-(3-phenylprop-2-enoylamino)ethyl] 3-phenylprop-2-enoate
• 化学式: C₂₈H₂₇NO₅
• 分子量: 457.5
• InChiKey: CUXXAUBWEIJETF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  34
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  73.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• COMPOUNDS AS ANTI-MALARIALS AND THEIR PROCESS OF PREPARATION
  申请人：Council of Scientific and Industrial Research

  公开号：EP3209639B1

  公开（公告）日：2020-09-16
• Aromatic Derivatives As Anti-Malarial
  申请人：Council of Scientific & Industrial Research

  公开号：US20190106380A1

  公开（公告）日：2019-04-11

  The present invention discloses anti-malarial compound of formula (I) Formula (I) wherein, X is selected from O or NH; R 1 , R 2 , R 3 , R 4 and R 5 is selected from H or OMe or CH 3 , —CH 2 —O—CH 2 — or —CH═CH—CH═CH—; Y is selected from O or NH and R 6 , R 7 is selected from the following compounds: or pharmaceutically acceptable salts thereof, process for preparation and a pharmaceutical composition containing the same.