N-Acetylglucosaminitol | 4271-28-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-Acetylglucosaminitol
• 英文别名: 2-(Acetylamino)-2-deoxyhexitol；N-(1,3,4,5,6-pentahydroxyhexan-2-yl)acetamide
• CAS: 4271-28-7；10486-91-6；10486-92-7；20874-63-9；22430-19-9；23583-39-3；23643-27-8
• 化学式: C₈H₁₇NO₆
• 分子量: 223.226
• InChiKey: DWAICOVNOFPYLS-UHFFFAOYSA-N

物化性质

• 熔点：
  174-176 °C
• 沸点：
  656.5±55.0 °C(Predicted)
• 密度：
  1.434±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.6
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  130
• 氢给体数：
  6
• 氢受体数：
  6

安全信息

• WGK Germany：
  3
• 海关编码：
  2924199090

文献信息

• OLIGOSACCHARIDE COMPOUND FOR INHIBITING ENDOGENOUS COAGULATION FACTOR X-ENZYME COMPLEX, AND PREPARATION METHOD THEREFOR AND USES THEREOF
  申请人：Jiuzhitang Co., Ltd.

  公开号：EP3569608A1

  公开（公告）日：2019-11-20

  A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containing the mixture, and uses thereof serving as an intrinsic factor X-enzyme (Xase) inhibitor in the preparation of drugs for preventing and/or treating thrombotic diseases.

  一种具有抗血栓活性的纯化寡糖化合物或其同源化合物及其药学上可接受的盐的混合物、该混合物的制备方法、含有该混合物的药物组合物，以及其在制备预防和/或治疗血栓性疾病的药物中作为内在因子X酶（Xase）抑制剂的用途。
• OLIGOSACCHARIDE COMPOUND FOR INHIBITING INTRINSIC COAGULATION FACTOR X-ENZYME COMPLEX, AND PREPARATION METHOD THEREFOR AND USES THEREOF
  申请人：Jiuzhitang Co., Ltd.

  公开号：US20200254003A1

  公开（公告）日：2020-08-13

  A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containing the mixture, and uses thereof serving as an intrinsic factor X-enzyme (Xase) inhibitor in the preparation of drugs for preventing and/or treating thrombotic diseases.