5,5,6,6,7,7,8,8,9,9,10,10,10-十三氟癸酸 | 26564-97-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 5,5,6,6,7,7,8,8,9,9,10,10,10-十三氟癸酸
• 英文名称: 5,5,6,6,7,7,8,8,9,9,10,10,10-tridecafluorodecanoic Acid
• CAS: 26564-97-6
• 化学式: C₁₀H₇F₁₃O₂
• 分子量: 406.144
• InChiKey: FTTVKNABRRCQHK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  25
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  15

反应信息

• 作为反应物：
  描述：

  5,5,6,6,7,7,8,8,9,9,10,10,10-十三氟癸酸 在 lithium aluminium tetrahydride 、 硫酸 、 水 、 氢溴酸 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 生成 1H,1H,2H,2H,3H,3H,4H,4H-perfluorodecyl bromide
  参考文献：
  名称：

  Synthèse d'acides ω perfluoroalkylalcanoı̈ques et d'ω perfluoroalkylalcanols

  摘要：

  DOI：

  10.1016/s0022-1139(99)00078-0
• 作为产物：
  描述：

  1-碘-1H,1H,2H,2H-全氟辛烷 在 氢氧化钾 、 potassium carbonate 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 27.0h， 生成 5,5,6,6,7,7,8,8,9,9,10,10,10-十三氟癸酸
  参考文献：
  名称：

  Convenient synthesis of thiols and disulfides in the polyfluorinated series incorporating a butylic spacer

  摘要：

  New fluorinated thiols R-F(CH2)(p)SH and disulfides [R-F(CH2)(p)S](2) containing a butylic spacer (p=4) between the perfluorinated part and the thiol (or disulfide) function were easily obtained in good yields with a purity higher than 98%. This allows us to obtain homologues (p>4) for their use as synthetic intermediates or as constituents for molecular organized systems. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00303-8

文献信息

• Synthèse d'acides ω perfluoroalkylalcanoı̈ques et d'ω perfluoroalkylalcanols
  作者：D. Tra Anh、H. Blancou、A. Commeyras

  DOI：10.1016/s0022-1139(99)00078-0

  日期：1999.7
• Nouveaux procédés de préparation des isocyanates F-alkylés linéaires ou ramifiés à partir des iodures de 2-F-alkyléthyle
  作者：P. Lucas、M.A. Jouani、H. Trabelsi、A. Cambon

  DOI：10.1016/s0022-1139(98)00235-8

  日期：1998.10

  Isocyanates are extremely versatile compounds in organic synthesis, but their synthesis is not easy. One of the most convenient methods uses acids as intermediates. In the F-alkyl series, it is sometimes difficult to obtain them by a general way. We have managed an efficient synthetic route to F-alkyl acids through malonates from 2-F-alkylethyl iodides.
• Synthèse d’acides α-aminés racémiques à chaı̂ne perfluoroalkylée
  作者：D TraAnh、H Blancou、A Commeyras

  DOI：10.1016/s0022-1139(98)00340-6

  日期：1999.2

  The simple and effective syntheses of racemic alpha-amino-acids of general formula R-F(CH2)(n-1)Y (Y=CH(NH2)CO2H) (R-F=C6F13, C8F17; n=3,10) have been described, (C) 1999 Elsevier Science S.A. All rights reserved.
• Convenient synthesis of thiols and disulfides in the polyfluorinated series incorporating a butylic spacer
  作者：Natacha Mureau、Frédéric Guittard、Serge Géribaldi

  DOI：10.1016/s0040-4039(00)00303-8

  日期：2000.4

  New fluorinated thiols R-F(CH2)(p)SH and disulfides [R-F(CH2)(p)S](2) containing a butylic spacer (p=4) between the perfluorinated part and the thiol (or disulfide) function were easily obtained in good yields with a purity higher than 98%. This allows us to obtain homologues (p>4) for their use as synthetic intermediates or as constituents for molecular organized systems. (C) 2000 Elsevier Science Ltd. All rights reserved.