2-(non-1-enyl)-4-hydroxyquinoline N-oxide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-(non-1-enyl)-4-hydroxyquinoline N-oxide
• 英文别名: 1-hydroxy-2-non-1-enylquinolin-4-one
• 化学式: C₁₈H₂₃NO₂
• 分子量: 285.4
• InChiKey: LOUOCBKBIWBTTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOUND FOR USE AGAINST PATHOGENIC NEISSERIA AND HAEMOPHILUS SPECIES AND MORAXELLA CATARRHALIS
  申请人：Universität Konstanz

  公开号：EP3502095A1

  公开（公告）日：2019-06-26

  The present invention relates to a compound, which can be used in the prevention and treatment of infections with pathogenic Neisseria species, in particular N. gonorrhoeae and N. meningitidis (the gonococcus and the meningococcus, respectively), and other pathogenic bacteria (e.g. Haemophilus species or Moraxella catarrhalis ), and which can be used for disinfecting a substrate from said bacteria. Moreover, the present invention relates to a corresponding pharmaceutical composition comprising said compound.

  本发明涉及一种化合物，可用于预防和治疗致病奈瑟菌属（特别是淋病奈瑟菌和脑膜炎奈瑟菌）以及其他致病细菌（例如衣原体属或喜马拉雅猫杆菌）感染，并可用于消毒受到这些细菌污染的基质。此外，本发明涉及包含该化合物的相应药物组合物。
• Compound for Use Against Pathogenic Neisseria and Haemophilus Species and Moraxella Catarrhalis
  申请人：Universität Konstanz

  公开号：US20210169869A1

  公开（公告）日：2021-06-10

  The present invention relates to a compound, which can be used in the prevention and treatment of infections with pathogenic Neisseria species, in particular N. gonorrhoeae and N. meningitidis (the gonococcus and the meningococcus, respectively), and other pathogenic bacteria (e.g. Haemophilus species or Moraxella catarrhalis ), and which can be used for disinfecting a substrate from said bacteria. Moreover, the present invention relates to a corresponding pharmaceutical composition comprising said compound.