10,13-dimethyl-docos-11-yne-10,13-diol | 69727-13-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 10,13-dimethyl-docos-11-yne-10,13-diol
• 英文别名: 10,13-Dimethyl-docos-11-in-10,13-diol；10,13-Dimethyl-11-docosyne-10,13-diol；10,13-dimethyldocos-11-yne-10,13-diol
• CAS: 69727-13-5
• 化学式: C₂₄H₄₆O₂
• 分子量: 366.628
• InChiKey: SVJREAUWQPERAY-UHFFFAOYSA-N

物化性质

• 熔点：
  82-83 °C(Solv: ligroine (8032-32-4))
• 沸点：
  327.8±10.0 °C(Predicted)
• 密度：
  0.909±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  acetylene-bis-magnesium bromide 、 2-甲基癸醇 在 乙醚 作用下， 生成 10,13-dimethyl-docos-11-yne-10,13-diol
  参考文献：
  名称：

  Petrow; Karlik, Zhurnal Obshchei Khimii, 1941, vol. 11, p. 1102

  摘要：

  DOI：

文献信息

• Comparative phytotoxicity of four monoterpenes against Cassia occidentalis
  作者：H P SINGH、DAIZY R BATISH、S KAUR、H RAMEZANI、R K KOHLI

  DOI：10.1111/j.1744-7348.2002.tb00202.x

  日期：2002.10

  SummaryThe effect of four monoterpenes ‐ citronellol, citronellal, cineole and linalool ‐ on the germination, growth and physiology of Cassia occidentalis was investigated. All four monoterpenes reduced germination of C. occidentalis seeds but to varying extents. Citronellal and linalool completely inhibited germination beyond the concentrations of 55 and 110 μM, respectively, whereas in response to treatment of citronellol no germination was observed beyond 330 μM. Further, the growth of seedlings, measured in terms of seedling length and biomass, was also adversely affected. A reduction in chlorophyll content of the cotyledonary leaves of C. occidentalis was also noticed, indicating an adverse effect on photosynthesis. Likewise, respiratory ability of growing seeds was also impaired in response to all four monoterpenes, clearly indicating that monoterpenes affect energy metabolism. On the basis of overall phytotoxicity, potency of monoterpenes was in the order of citronellal > linalool > citronellol > cineole. The results from this study suggest that both citronellal and linalool possess strong phytotoxic potential and can thus serve as lead molecules for the synthesis of bioherbicides.
• PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT
  申请人：Kenny Louise

  公开号：US20130295679A1

  公开（公告）日：2013-11-07

  A method of predicting a SGA infant in a patient at a pre-symptomatic gestational stage is described. The method comprises a step of assaying a biological sample from the patient for an abundance of a plurality of metabolite biomarkers selected from the 19 metabolite biomarkers of Table IV, correlating the abundance of the plurality of metabolite biomarkers with a metabolite fingerprint of SGA shown in Table IV, and predicting SGA based on the level of correlation between the abundance of the plurality of metabolite biomarkers and the metabolite fingerprint of Table IV.