pentacosan-13-ol | 138966-97-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: pentacosan-13-ol
• 英文别名: 13-Pentacosanol
• CAS: 138966-97-9
• 化学式: C₂₅H₅₂O
• 分子量: 368.687
• InChiKey: VQPXKBBANDVCGT-UHFFFAOYSA-N

物化性质

• 熔点：
  79.5-80.5 °C
• 沸点：
  418.3±13.0 °C(Predicted)
• 密度：
  0.839±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  11.9
• 重原子数：
  26
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  pentacosan-13-ol 在 palladium on activated charcoal sodium azide 、 氢气 、 三乙胺 作用下， 以 四氢呋喃 、 正己烷 、 N,N-二甲基甲酰胺 为溶剂， 20.0~85.0 ℃ 、427.48 kPa 条件下， 反应 7.25h， 生成 di-(n-dodecyl)methylamine
  参考文献：
  名称：

  Synthesis and antimicrobial activity of symmetrical two-tailed dendritic tricarboxylato amphiphiles

  摘要：

  Two series of water-soluble, symmetrical two-tailed homologous dendritic amphiphiles-R2NCONHC((CH2)(2)COOH)(3), 2(n,n), and R2CHNHCONHC((CH2))(2)COOH)(3), 3(n,n), where R = n-CnH2n+1-were synthesized and compared to R"NHCONHC((CH2)(2)CoOH)(3), 1(n), R" = n-CnH2n+1, to determine whether antimicrobial activity was influenced by total or individual alkyl chain lengths, and whether antimicrobial activity depends on hydrophobicity or tail topology (one or two). In a broad screen of 11 microorganisms, 2(n,n) and 3(n,n) generally displayed higher minimal inhibitory concentrations (MICs) than I(n) against growth as measured by broth microdilution assays. Chain-length specificity was observed against Candida albicans as 1(16), 2(8,8), and 3(8,8) showed the lowest MIC in their respective series. The one case where two-tailed compounds displayed the lowest MICs-3(10,10), 15 mu M; 3(11,11), 7.2 mu M; and 3(12,12), 6.9 mu M-was against Cryptococcus neoformans. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2007.03.017
• 作为产物：
  描述：

  二十五烷-13-酮 在 lithium tri-t-butoxyaluminum hydride 作用下， 以 四氢呋喃 为溶剂， 生成 pentacosan-13-ol
  参考文献：
  名称：

  The question of remote steric effects

  摘要：

  Remote steric effects, thought to arise from long hydrocarbon chains coiling about reactive sites, are absent in three non-aqueous systems designed to maximize the effect.

  DOI：

  10.1016/s0040-4039(00)76214-9

文献信息

• METHODS FOR CONTROLLING SURFACE FUNCTIONALITY OF METAL OXIDE NANOPARTICLES, METAL OXIDE NANOPARTICLES HAVING CONTROLLED FUNCTIONALITY, AND USES THEREOF
  申请人：White Meghann A.

  公开号：US20080299046A1

  公开（公告）日：2008-12-04

  Methods for controlling surface functionality of metal oxide nanoparticles, nanoparticles having controlled surface functionality, and uses thereof are described herein. Methods for controlling the surface functionality of a metal oxide nanoparticle are can include attaching a ligand to a metal oxide nanoparticle, where the ligand can include a functional portion that is capable of forming an irreversible bond with an object at a site that is complementary to the functional portion without reacting with other reactive sites that may be present. Moreover, metal oxide nanoparticles having versatile ligands can include an anchoring portion that binds to the surface of the metal oxide nanoparticle and a functional portion that is capable of forming an irreversible bond with an object at a site that is complementary to the functional portion without reacting with other reactive sites that may be present. Uses thereof can include cancer detection, electronics, cosmetics, cellular delivery carriers, magnetic storage media, drug delivery carriers, nanocomposite formation for improved mechanical properties, and the like.

  金属氧化物纳米颗粒表面功能的控制方法，具有受控表面功能的纳米颗粒，以及它们的用途在此进行描述。控制金属氧化物纳米颗粒表面功能的方法可以包括将配体连接到金属氧化物纳米颗粒上，其中配体可以包括一个功能部分，该功能部分能够与物体上的一个与功能部分互补的位置形成不可逆结合，而不会与可能存在的其他反应位点发生反应。此外，具有多功能配体的金属氧化物纳米颗粒可以包括一个锚定部分，该部分与金属氧化物纳米颗粒的表面结合，以及一个功能部分，该功能部分能够与物体上的一个与功能部分互补的位置形成不可逆结合，而不会与可能存在的其他反应位点发生反应。其用途可以包括癌症检测、电子学、化妆品、细胞递送载体、磁存储介质、药物递送载体、用于改善机械性能的纳米复合材料形成等。
• Long‐Range Self‐Assembly of an Electron‐Deficient Hexaazatrinaphthylene with Out‐of‐Plane Substituents
  作者：Yi‐Ru Chen、Yong‐Yun Zhang、Ming‐Che Yeh、Ying‐Ting Luo、Chi Wi Ong

  DOI：10.1002/cplu.201900593

  日期：2020.4

  The unprecedented time‐dependent long‐range supramol‐ecular assembly of electron‐deficient hexaazatrinaphthylene (HATN) core based on peripheral crowding with three out‐of‐plane cyclic ketals is reported. The single‐crystal X‐ray structure of the diethyl derivative provided detailed information as to how four molecules in a repeating unit were packed in order to avoid steric crowding of the out‐of‐plane

  据报道，基于外围拥挤并带有三个平面外环状缩酮，缺电子的六氮杂萘（HATN）核具有前所未有的时间依赖性远距离超分子组装。二乙基衍生物的单晶X射线结构提供了有关重复单元中如何堆积四个分子的详细信息，从而避免平面外环状缩酮侧链的空间拥挤，从而提供锁定和固定作用以稳定自组装结构。偏振光学显微镜（POM）和差示扫描量热法（DSC）在冷却过程中没有立即显示出任何相变。令我们惊讶的是，POM图像显示24小时后高达100μm的球晶形核。X射线衍射数据进一步证实了这些软晶体形成了六角形晶体。新材料的远程自组装在紫外可见吸收光谱中显示出轻微的红移，并通过计算方法进一步证实。
• Effect of Aglycon Structure on Saccharide Elongation by Cells
  作者：Tamami Kimura、Maria Carmelita Z. Kasuya、Kenichi Hatanaka、Koji Matsuoka

  DOI：10.1002/cbdv.201400278

  日期：2015.2

  Alkyl N‐acetyl‐β‐D‐glucosaminide (GlcNAc primers) with different aglycon moieties were synthesized and used to determine the effect of the aglycon structure on cellular saccharide elongation. Dodecyl N‐acetyl‐β‐D‐glucosaminide (GlcNAc‐C12), tridecan‐7‐yl N‐acetyl‐β‐D‐glucosaminide (GlcNAc‐2C6), and pentacosan‐13‐yl N‐acetyl‐β‐D‐glucosaminide (GlcNAc‐2C12) primers were synthesized by glycosylation of

  合成了具有不同苷元部分的烷基 N-乙酰基-β-D-氨基葡萄糖（GlcNAc 引物），并用于确定苷元结构对细胞糖延伸的影响。十二烷基 N-乙酰基-β-D-氨基葡萄糖 (GlcNAc-C12)、十三烷基-7-基 N-乙酰基-β-D-氨基葡萄糖 (GlcNAc-2C6) 和五十二烷-13-基 N-乙酰基-β-D-氨基葡萄糖 (GlcNAc-2C12) 引物是通过十二聚糖-1-醇、十三聚糖-7-醇和戊聚糖-13-醇分别与过乙酰氨基葡萄糖进行糖基化合成的。将这些引物引入小鼠 B16 黑色素瘤细胞以制备糖脂。孵育 48 小时后，结果表明 GlcNAc-C12 被拉长，得到 NeuAc-Gal-GlcNAc-C12。GlcNAc-2C6 也被拉长得到 Gal-GlcNAc-2C6 和 NeuAc-Gal-GlcNAc-2C6。另一方面，GlcNAc-2C12 引物没有被延长。显着地，
• Catalytic Synthesis of Conjugated Azopolymers from Aromatic Diazides
  作者：John M. Andjaba、Christopher J. Rybak、Zhiyang Wang、Jianheng Ling、Jianguo Mei、Christopher Uyeda

  DOI：10.1021/jacs.1c00447

  日期：2021.3.17

  Conjugated polymers containing main chain azoarene repeat units are synthesized by a dinickel catalyzed N=N coupling reaction of aromatic diazides. The polymerization exhibits broad substrate scope and is compatible with heterocycles commonly featured in high performance organic materials, including carbazole, thiophene, propylenedioxythiophene (ProDOT), diketopyrrolopyrrole (DPP), and isoindigo. Copolymerizations

  含有主链偶氮芳烃重复单元的共轭聚合物是通过二镍催化的芳族二叠氮化物的 N=N 偶联反应合成的。该聚合反应具有广泛的底物范围，并且与高性能有机材料中常见的杂环相容，包括咔唑、噻吩、丙烯二氧噻吩 (ProDOT)、二酮吡咯并吡咯 (DPP) 和异靛蓝。可以使用单体混合物进行共聚，并且可以使用单叠氮链终止剂来安装明确定义的端基。由于偶氮键的功能性，偶氮聚合物具有独特的性质。例如，氮质子化导致 LUMO 降低和红移吸收带。此外，N=N 键具有较低的 π* 水平，允许偶氮聚合物在温和条件下可逆还原。
• Detergents for cold-water cleaning
  申请人：Stepan Company

  公开号：US10421930B2

  公开（公告）日：2019-09-24

  Detergents useful for cold-water cleaning and mid-chain headgroup and alkylene-bridged surfactants useful therein are disclosed. The mid-chain headgroup surfactant has a C14-C30 alkyl chain and a polar group bonded to a central zone carbon of the alkyl chain. The alkylene-bridged surfactant has a C12-C18 alkyl chain, a polar group, and a C1-C2 alkylene group bonded to the polar group and a central zone carbon of the C12-C18 alkyl chain. Preferred surfactants in these classes are alcohol sulfates, alcohol ethoxylates, ether sulfates, sulfonates, arylsulfonates, alcohol phosphates, amine oxides, quaterniums, betaines, and sulfobetaines. Surprisingly, detergents formulated with the surfactants provide outstanding cold-water performance in removing greasy stains such as bacon grease, butter, cooked beef fat, or beef tallow from soiled articles.

  本发明公开了可用于冷水清洁的洗涤剂以及可用于冷水清洁的中链头基表面活性剂和亚烷基桥接表面活性剂。中链头表面活性剂具有 C14-C30 烷基链和一个与烷基链中心区碳键合的极性基团。烯桥表面活性剂具有 C12-C18 烷基链、一个极性基团以及一个与极性基团和 C12-C18 烷基链中心区碳键合的 C1-C2 烯基。这几类表面活性剂中较好的有醇硫酸盐、醇聚氧乙烯醚、醚硫酸盐、磺酸盐、芳基磺酸盐、醇磷酸盐、氧化胺、季铵盐、甜菜碱和磺基甜菜碱。令人惊奇的是，使用这些表面活性剂配制的洗涤剂在去除脏污物品上的油渍（如培根油、黄油、熟牛肉脂肪或牛脂）方面具有出色的冷水性能。