2-(1,3-Diazetidin-2-ylperoxymethyl)-4-ethoxy-6-methoxyquinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-(1,3-Diazetidin-2-ylperoxymethyl)-4-ethoxy-6-methoxyquinoline
• 英文别名: 2-(1,3-diazetidin-2-ylperoxymethyl)-4-ethoxy-6-methoxyquinoline
• 化学式: C₁₅H₁₉N₃O₄
• 分子量: 305.33
• InChiKey: WIHWCWBIBLQMTJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  73.9
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF
  申请人：Correa Arlene Goncalves

  公开号：US20100196476A1

  公开（公告）日：2010-08-05

  The present invention describes novel 4-quinolinones corresponding to formula (I) and quinoline derivatives thereof as formula (II), process of preparation thereof, pharmaceutical formulations comprising said 4-quinolinones and pharmaceutical application thereof for diseases related to disorders of white blood cells, such as inflammatory and autoimmune diseases, including rheumatism, as well as the use as anti-coagulant, antivenin, analgesic and for antithrombotic purposes.