4,4-Dimethylcycloheptanol | 35099-84-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4,4-Dimethylcycloheptanol
• 英文别名: (+/-)-4-hydroxy-1.1-dimethyl-cycloheptane；(+/-)-4-Hydroxy-1.1-dimethyl-cycloheptan；4,4-Dimethylcycloheptan-1-ol
• CAS: 35099-84-4
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: AHTKROFORNYYSL-UHFFFAOYSA-N

物化性质

• 沸点：
  196.8±8.0 °C(Predicted)
• 密度：
  0.891±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4,4-Dimethylcycloheptanol 在 硝酸 作用下， 生成 3,3-dimethyl-heptanedioic acid
  参考文献：
  名称：

  Multiple attention systems in perceptual categorization

  摘要：

  Five observers categorized inverted L-shaped stimuli according to the length of the horizontal line segment. A centrally located spatial cue preceded the stimulus on each trial. On 80% of the trials, the (relevant) horizontal line segment fell within the cued location, and on 20% of the trials the (irrelevant) vertical line segment fell within the cued location. The empirical results provide support for the hypothesis that perceptual attention can focus on the stimulus attribute inside the spatially cued location at the same time that decisional attention is focused on the (relevant) horizontal attribute-that is, the results suggest that perceptual and decisional attention can function independently during categorization. Decision bound models and extended generalized context models that assume separate perceptual and decisional attention systems were fitted to the data. Versions of the models that assume that the spatial cue affected perceptual attention were superior to versions that assume no effect on perceptual attention. These theoretical analyses support the functional independence hypothesis and suggest that formal theories of categorization should model the effects of perceptual and decisional attention separately.

  DOI：

  10.3758/bf03194934
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium nitrite 作用下， 生成 4,4-Dimethylcycloheptanol
  参考文献：
  名称：

  Multiple attention systems in perceptual categorization

  摘要：

  Five observers categorized inverted L-shaped stimuli according to the length of the horizontal line segment. A centrally located spatial cue preceded the stimulus on each trial. On 80% of the trials, the (relevant) horizontal line segment fell within the cued location, and on 20% of the trials the (irrelevant) vertical line segment fell within the cued location. The empirical results provide support for the hypothesis that perceptual attention can focus on the stimulus attribute inside the spatially cued location at the same time that decisional attention is focused on the (relevant) horizontal attribute-that is, the results suggest that perceptual and decisional attention can function independently during categorization. Decision bound models and extended generalized context models that assume separate perceptual and decisional attention systems were fitted to the data. Versions of the models that assume that the spatial cue affected perceptual attention were superior to versions that assume no effect on perceptual attention. These theoretical analyses support the functional independence hypothesis and suggest that formal theories of categorization should model the effects of perceptual and decisional attention separately.

  DOI：

  10.3758/bf03194934

文献信息

• [EN] SYNTHESIS OF SUBSTITUTED CYCLOPENTADIENE COMPOUNDS AND METALLOCENES<br/>[FR] SYNTHÈSE DE COMPOSÉS DE CYCLOPENTADIÈNE SUBSTITUÉS ET DE MÉTALLOCÈNES
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2020068420A1

  公开（公告）日：2020-04-02

  A method of synthesizing a substituted cyclopentadiene compound. The synthesis comprises a step of cyclizing, in the presence of a phosphorous pentoxide/methanesulfonic acid reagent, an alpha,beta-unsaturated carboxylic acid, cycloalkyl ester compound to make a substituted cyclopentenone compound, and converting the substituted cyclopentenone compound to the substituted cyclopentadiene compound. Also, a method of synthesizing a substituted metallocene compound comprising a metal-(substituted cyclopentadienyl ligand) complex, wherein the substituted cyclopentadienyl ligand is made from the substituted cyclopentadiene compound. A metal-(substituted cyclopentadienyl ligand) complex and substituted metallocene compound made by the method and a substituted metallocene catalyst made therefrom.

  一种合成取代环戊二烯化合物的方法。该合成包括在磷五氧化三磷/甲磺酸试剂存在下，通过环化步骤将α，β-不饱和羧酸，环烷基酯化合物环化为取代环戊酮化合物，并将取代环戊酮化合物转化为取代环戊二烯化合物。此外，还包括一种合成含金属-(取代环戊二烯基配体)复合物的取代茂金属化合物的方法，其中取代环戊二烯基配体是由取代环戊二烯化合物制备的。由该方法制备的金属-(取代环戊二烯基配体)复合物和取代茂金属化合物，以及由此制备的取代茂金属催化剂。
• [EN] SYNTHESIS OF CYCLOPENTENONES<br/>[FR] SYNTHÈSE DE CYCLOPENTÉNONES
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2020068419A1

  公开（公告）日：2020-04-02

  A method comprising synthesizing a substituted cyclopentenone compound via reaction of a substituted cycloalkyl acrylate ester in the presence of phosphorous pentoxide/methanesulfonic acid reagent to make the substituted cyclopentenone compound.

  一种方法包括在存在磷酸五氧化磷/甲磺酸试剂的情况下，通过对取代的环烷基丙烯酸酯进行反应合成取代的环戊烯酮化合物，以制备所述的取代的环戊烯酮化合物。
• ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES
  申请人：Marfat Anthony

  公开号：US20070161681A1

  公开（公告）日：2007-07-12

  Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of the formula: wherein the substituents are as defined in the specification.

  以下化合物可用作PDE4的抑制剂，用于治疗由嗜酸性粒细胞的活化和脱颗粒调控的疾病，特别是哮喘、慢性支气管炎和慢性阻塞性肺疾病，其化学式如下：其中取代基如规范中所定义。
• HEINZ, UWE;ADAMS, ELISABETH;KLINTZ, RALF;WELZEL, PETER, TETRAHEDRON., 46,(1990) N2, C. 4217-4230
  作者：HEINZ, UWE、ADAMS, ELISABETH、KLINTZ, RALF、WELZEL, PETER

  DOI：——

  日期：——
• SYNTHESIS OF CYCLOPENTENONES
  申请人：Dow Global Technologies LLC

  公开号：EP3856709A1

  公开（公告）日：2021-08-04