2-[2-[2-[2-(2-Chloroethoxy)ethylsulfanyl]ethoxy]ethylsulfanyl]ethanol | 208517-90-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-[2-[2-(2-Chloroethoxy)ethylsulfanyl]ethoxy]ethylsulfanyl]ethanol
• 英文别名: 2-[2-[2-[2-(2-chloroethoxy)ethylsulfanyl]ethoxy]ethylsulfanyl]ethanol
• CAS: 208517-90-2
• 化学式: C₁₀H₂₁ClO₃S₂
• 分子量: 288.86
• InChiKey: XUROOEUNIKBZIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  16
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  89.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  bis (2-chloroethyl) sulphide 在 KF/Al₂O₃ 、 水 作用下， 生成 硫二甘醇 、 2,2'-[氧基二(2,1-乙二基硫代)]二-乙醇 、 6,12,18,24,30,36-hexaoxa-3,9,15,21,27,33,39-heptathiahentetracontane-1,41-diol 、 6,12,18-trioxa-3,9,15,21-tetrathia-tricosane-1,23-diol 、 6,12,18,24-tetraoxa-3,9,15,21,27-pentathia-nonacosane-1,29-diol 、 2-[2-[2-[2-(2-Chloroethoxy)ethylsulfanyl]ethoxy]ethylsulfanyl]ethanol 、 6,12,18,24,30-pentaoxa-3,9,15,21,27,33-hexathia-pentatriacontane-1,35-diol 、 6,12-dioxa-3,9,15-trithia-heptadecane-1,17-diol
  参考文献：
  名称：

  Degradation of Sulfur Mustard on KF/Al₂O₃ Supports: Insights into the Products and the Reactions Mechanisms

  摘要：

  The degradation of the warfare agent sulfur Mustard (HD) adsorbed onto KIF/Al2O3 sorbents is described. These processes were explored by MAS NMR. using C-13-labeled sulfur mustard (HD*) and LC-MS techniques. Out study on the detoxification of this blister agent showed the formation of nontoxic substitution and less-toxic elimination products (t(1/2) = 3.5-355 h) Interestingly, the reaction rates Were found to be affected by MAS conditions, i.e., by a centrifugation effect. The products and the mechanisms of these processes tire discussed.

  DOI：

  10.1021/jo901713c

文献信息

• Degradation of Sulfur Mustard on KF/Al₂O₃ Supports: Insights into the Products and the Reactions Mechanisms
  作者：Yossi Zafrani、Michael Goldvaser、Shai Dagan、Liron Feldberg、Dana Mizrahi、Daniel Waysbort、Eytan Gershonov、Ishay Columbus

  DOI：10.1021/jo901713c

  日期：2009.11.6

  The degradation of the warfare agent sulfur Mustard (HD) adsorbed onto KIF/Al2O3 sorbents is described. These processes were explored by MAS NMR. using C-13-labeled sulfur mustard (HD*) and LC-MS techniques. Out study on the detoxification of this blister agent showed the formation of nontoxic substitution and less-toxic elimination products (t(1/2) = 3.5-355 h) Interestingly, the reaction rates Were found to be affected by MAS conditions, i.e., by a centrifugation effect. The products and the mechanisms of these processes tire discussed.