Di-<2-chlorphenyl>-phenylphosphin | 66185-98-6

• 物质功能分类: 化学试剂 - 有机试剂 - 膦配体
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Di-<2-chlorphenyl>-phenylphosphin
• 英文别名: bis-(2-chloro-phenyl)-phenyl-phosphane；P(C6H5)(2-C6H4Cl)2；Phosphine, bis(2-chlorophenyl)phenyl-；bis(2-chlorophenyl)-phenylphosphane
• CAS: 66185-98-6
• 化学式: C₁₈H₁₃Cl₂P
• 分子量: 331.181
• InChiKey: WUUKPOCGPVEOMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  Di-<2-chlorphenyl>-phenylphosphin 以 氘代氯仿 、 二氯甲烷 为溶剂， 生成 trans-[PdCl2(P(C6H4-4-Cl)3)2]
  参考文献：
  名称：

  Transition metal complexes containing P(C6H5)(C6H4Cl-2)2. The effect of added Lewis bases as a probe for substitution reactions occurring in ambient temperature Suzuki couplings catalyzed by Pd/P(C6H5)(C6H4Cl-2)2

  摘要：

  The reactivity of the d(8) transition metal complexes, [NiBr2(CH3OCH2CH2OCH3)] and MCl2L2 (M = Pd, Pt; L = CH3CN; L-2 = 1,5-cyclooctadiene), towards P(C6H5)(C6H4Cl-2)(2) (1) was investigated. While treatment of [PdCl2(cod)] with 2 equiv of 1 resulted in displacement of the weakly coordinating cyclooctadiene and formation of [PdCl2(P(C6H5)(C6H4Cl-2)(2))(2)], analogous reactions with [PtCl2(cod)] afforded the monosubstituted species [PtCl2(cod)(P(C6H5)(C6H4Cl-2)(2))]. The disubstituted complex [PtCl2(P(C6H5)(C6H4Cl-2)(2))(2)] was successfully obtained by treatment of [PtCl2(NCCH3)(2)] with 2 equiv of 1. However, attempts to react I with [NiBr2(CH3OCH2CH2OCH3)] were unsuccessful. The chlorinated triphenyl phosphine is quite labile and is readily displaced from [PdCl2(P(C6H5)(C6H4Cl-2)(2))(2)] by various Lewis bases including nitrogen containing ligands such as 2,2-bipyridine. The molecular structure of trans-[PdCl2(P(C6H5)(C6H4Cl-2)(2))(2)] was determined by X-ray diffraction and represents the first molecular structure determination of a transition metal complex containing 1. This complex crystallizes in the monoclinic space group P2(1)/n with a = 10.3928(3) Angstrom, b = 16.0102(4) Angstrom, c = 13.1884(4) Angstrom, beta = 90.714(2)degrees, and Z = 4. Key geometric parameters include Pd-Cl(1) = 2.309(1) Angstrom, Pd-P(1) = 2.334(1) Angstrom,- Pd-P(1)-C(7) = 118.3(2)degrees, Pd-P(1)-C(1) = 115.3(2)degrees, C(1)-C(6)-Cl(2) = 120.7(4)degrees and Cl(1)-Pd-P(1) = 85.86(4)degrees. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01141-6
• 作为产物：
  描述：

  2-溴氯苯 、 苯基二氯化磷 生成 Di-<2-chlorphenyl>-phenylphosphin
  参考文献：
  名称：

  726. 5,10-二取代的5,10-二氢磷杂蒽及其衍生物的合成和立体化学

  摘要：

  DOI：

  10.1039/jr9640003770

文献信息

• [EN] PREPARING AN UNSATURATED CARBOXYLIC ACID SALT FROM AN ALKENE AND CARBON DIOXIDE USING A HETEROGENEOUS BASE<br/>[FR] PRÉPARATION D'UN SEL D'ACIDE CARBOXYLIQUE INSATURÉ À PARTIR D'UN ALCÈNE ET DE DIOXYDE DE CARBONE À L'AIDE D'UNE BASE HÉTÉROGÈNE
  申请人：BASF SE

  公开号：WO2015173296A1

  公开（公告）日：2015-11-19

  Process for preparing an α,β-ethylenically unsaturated carboxylic acid salt, comprising, reacting an alkene and carbon dioxide in the presence of a carboxylation catalyst to obtain a catalyst-coordinated carboxylated intermediate, treating the catalyst- coordinated carboxylated intermediate with a heterogeneous base, and releasing the α,β-ethylenically unsaturated carboxylic acid salt, wherein the heterogeneous base comprises an organic basic moiety that is immobilized on a solid support. The process avoids accumulation of the conjugate acid of the base in the reaction medium.

  制备α，β-乙烯基不饱和羧酸盐的过程包括，在羧化催化剂存在下，使烯烃和二氧化碳反应，得到一个催化剂协同的羧化中间体；用异相碱处理催化剂协同的羧化中间体，释放α，β-乙烯基不饱和羧酸盐。其中，异相碱包括有机碱基固定在固体支撑上的基团。该过程避免了反应介质中碱的共轭酸的积累。
• [EN] PROCESS FOR PREPARING AN UNSATURATED CARBOXYLIC ACID SALT USING AN ARYLOXIDE<br/>[FR] PROCÉDÉ DE PRÉPARATION D'UN SEL D'ACIDE CARBOXYLIQUE INSATURÉ À L'AIDE D'UN OXYDE D'ARYLE
  申请人：BASF SE

  公开号：WO2015173277A1

  公开（公告）日：2015-11-19

  Catalytic process for preparing an α,β-ethylenically unsaturated carboxylic acid salt, wherein an alkene and carbon dioxide are reacted in the presence of a carboxylation catalyst and in the presence of a specific aryloxide to obtain the α,β-ethylenically unsaturated carboxylic acid salt, the carboxylation catalyst being a transition metal complex. The process allows for efficient preparation of α,β-ethylenically unsaturated carboxylic acid derivatives from CO2 and an alkene.

  该催化过程用于制备α，β-乙烯基不饱和羧酸盐，其中在羧化催化剂和特定芳基氧化物的存在下，烯烃和二氧化碳反应，从而获得α，β-乙烯基不饱和羧酸盐，羧化催化剂是过渡金属配合物。该过程允许从CO2和烯烃高效制备α，β-乙烯基不饱和羧酸衍生物。
• [EN] PROCESS FOR PREPARING AN UNSATURATED CARBOXYLIC ACID SALT<br/>[FR] PROCÉDÉ DE PRÉPARATION D'UN SEL D'ACIDE CARBOXYLIQUE INSATURÉ
  申请人：BASF SE

  公开号：WO2017178282A1

  公开（公告）日：2017-10-19

  The present invention relates to a catalytic process for preparing an α,β-ethylenically unsaturated carboxylic acid salt, comprising contacting an alkene and carbon dioxide with a carboxylation catalyst being a transition metal complex, an alkoxide, and an organic solvent, to obtain an α,β-ethylenically unsaturated carboxylic acid salt, the organic solvent being incompletely miscible with water at a pressure of 1 bar at at least one temperature T and selected from amides and ureas, T being a temperature in the range from 10°C to 90°C.

  本发明涉及一种催化制备α，β-乙烯基不饱和羧酸盐的过程，包括将烯烃和二氧化碳与羧化催化剂接触，该催化剂为过渡金属配合物、醇盐和有机溶剂，以获得α，β-乙烯基不饱和羧酸盐，所述有机溶剂在至少一温度T下在1巴压力下与水不完全混溶，所述有机溶剂选自酰胺和脲，T为10℃至90℃范围内的温度。
• [EN] PREPARING AN UNSATURATED CARBOXYLIC ACID SALT FROM AN ALKENE AND CARBON DIOXIDE USING A COVALENTLY IMMOBILIZED TRANSITION METAL COMPLEX<br/>[FR] PRÉPARATION D'UN SEL D'ACIDE CARBOXYLIQUE INSATURÉ À PARTIR D'UN ALCÈNE ET DE DIOXYDE DE CARBONE À L'AIDE D'UN COMPLEXE DE MÉTAL DE TRANSITION IMMOBILISÉ DE MANIÈRE COVALENTE
  申请人：BASF SE

  公开号：WO2015173295A1

  公开（公告）日：2015-11-19

  Process for preparing an α,β-ethylenically unsaturated carboxylic acid salt, comprising, reacting an alkene and carbon dioxide in the presence of a carboxylation catalyst and releasing the α,β-ethylenically unsaturated carboxylic acid salt with a base, wherein the carboxylation catalyst comprises a transition metal complex that is covalently immobilized on a solid support. The crude reaction product can be processed with little effort to obtain the carboxylic acid derivative at a purity level suitable for further processing into sanitary products.

  制备α，β-乙烯基不饱和羧酸盐的过程，包括在羧化催化剂的存在下反应烯烃和二氧化碳，并用碱释放α，β-乙烯基不饱和羧酸盐，其中羧化催化剂包括共价固定在固体支撑上的过渡金属配合物。粗反应产物可以经过少量处理，获得适合进一步加工成卫生产品的纯度水平的羧酸衍生物。
• Verfahren zur Herstellung von tertiären Phosphinen
  申请人：BASF Aktiengesellschaft

  公开号：EP0548682A1

  公开（公告）日：1993-06-30

  Herstellung von tertiären Phosphinen (I) durch Reduktion der entsprechenden Phosphinoxide (IIa) oder Phosphindihalogenide (IIb), indem man als Reduktionsmittel Silicium oder eine Siliciumlegierung verwendet.

  以硅或硅合金为还原剂，通过还原相应的膦氧化物 (IIa) 或膦二卤化物 (IIb) 制备叔膦 (I)。