1-Phenyl-1,2,4-triazolin-5-thion | 21434-18-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-Phenyl-1,2,4-triazolin-5-thion
• 英文别名: 2-phenyl-1H-1,2,4-triazole-3-thione
• CAS: 21434-18-4
• 化学式: C₈H₇N₃S
• 分子量: 177.23
• InChiKey: BVIRJZRMLOIHQT-UHFFFAOYSA-N

物化性质

• 沸点：
  260.4±23.0 °C(Predicted)
• 密度：
  1.33±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  59.7
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-Phenyl-1,2,4-triazolin-5-thion 生成 1-phenyl-5-[(2-phenyl-1,2,4-triazol-3-yl)disulfanyl]-1,2,4-triazole
  参考文献：
  名称：

  MOTIDZUKI, NOBUO;XAGIVARA, SYUNITI

  摘要：

  DOI：
• 作为产物：
  描述：

  1-苯基-1H-1,2,4-噻唑 在 sulfur 、 lithium tert-butoxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以74%的产率得到1-Phenyl-1,2,4-triazolin-5-thion
  参考文献：
  名称：

  In Situ Generation and Trapping of Aryllithium and Arylpotassium Species by Halogen, Sulfur, and Carbon Electrophiles

  摘要：

  A general method has been developed for in situ trapping of arylmetal intermediates by halogen, sulfur, ketone, and aldehyde electrophiles affording the functionalization of the most acidic position in arene Pentafluorobenzene, benzothiazole,and benzoxazole can be functionalized by using K3PO4 base. For less acidic arenes, tBuOLi base is required. Arenes with DMSO pK(a) values of 35 or less are reactive.

  DOI：

  10.1021/jo9015369

文献信息

• Three-Component Reaction for an Efficient Synthesis of Stable Phosphorus Ylides Using Mercapto Compounds
  作者：Zahra Hassani、Mohammad Reza Islami、Arman Moradi、Moazameh Yazdi Rouh-Alamini

  DOI：10.1080/10426500802208664

  日期：2009.3.10

  Stabilized phosphorus ylides were obtained from the three-component reaction between dialkyl acetylenedicarboxylate and sulfur compounds such as pyridine-2-thione, 2-furylmethanethiol, ethanedithioamide, and N-phenyl-1,2,4-triazole-3-thiol in the presence of triphenylphosphine in excellent yields.

  在乙炔二羧酸二烷基酯与硫化合物（如吡啶-2-硫酮、2-呋喃甲硫醇、乙二硫酰胺和 N-苯基-1,2,4-三唑-3-硫醇）的三组分反应中获得稳定的磷叶立德三苯基膦的高产率。
• METHOD OF SYNTHESIZING 1,2,4-TRIAZOLE-3-THIONE COMPOUNDS AND INTERMEDIATES THEREOF
  申请人：ORIENTAL (LUZHOU) AGROCHEMICALS CO., LTD.

  公开号：US20190127338A1

  公开（公告）日：2019-05-02

  Disclosed is a method of synthesizing 1,2,4-triazole-3-thione compounds and intermediates thereof. The method includes reacting a hydrazine with glyoxylic acid to form a hydrazono acetic acid intermediate followed by reacting the latter with thiocyanate to obtain the 1,2,4-triazole-3-thione compound. The raw materials involved in the present method are readily available, and the reaction is very specific in terms of regioselectivity, resulting in minimum by-product and high product yield. There are neither specific requirements for special equipment nor special operations such as high vacuum, high temperature, anhydrous and oxygen-free manipulations. The process is simple and generates minimum wastes, suitable for industrial production.

  本发明公开了一种合成1,2,4-三唑-3-硫醇化合物及其中间体的方法。该方法包括将肼与乙醛酸反应形成肼酮乙酸中间体，然后将后者与硫氰酸盐反应得到1,2,4-三唑-3-硫醇化合物。本方法所涉及的原材料易得，反应在区域选择性方面非常具体，产生的副产物很少且产率高。既无需特殊设备，也无需高真空、高温、无水和无氧操作等特殊要求。该过程简单，产生的废物很少，适合于工业生产。
• Sensitizer/Initiator Combination for Negative-Working Thermal-Sensitive Compositions Usable for Lithographic Plates
  申请人：Eastman Kodak Company

  公开号：EP2098367A1

  公开（公告）日：2009-09-09

  The radiation-sensitive composition and the negative working imageable element include a cationic IR absorber with tetraarylborate counteranion and an onium initiator with tetraarylborate counteranion. The use of these components provides high imaging sensitivity, good shelflife and high print run length.

  辐射敏感组合物和负片成像元素包括具有四芳基硼酸盐对阴离子的阳离子红外吸收剂和具有四芳基硼酸盐对阴离子的离子引发剂。使用这些组分提供高成像灵敏度，良好的货架寿命和高印刷运行长度。
• Triazolyl phosphorus esters as pesticides
  申请人：Ciba-Geigy Corporation

  公开号：US03932630A1

  公开（公告）日：1976-01-13

  Triazolylphosphorus compounds of the formula ##EQU1## wherein R.sub.1 represents hydrogen, alkyl, cycloalkyl, phenyl, benzyl or phenethyl, R.sub.2 represents alkylthio, alkylsulphinyl, alkylsulphonyl, phenthio, phenylsulphinyl, phenylsulphonyl, benzylthio, benzylsulphinyl or benzylsulphonyl, R.sub.3 represents alkyl, alkoxy, alkylthio or phenyl, R.sub.4 represents alkyl, and X represents oxygen or sulphur, Processes for their production and their use for pest control.

  式子为##EQU1##的Triazolylphosphorus化合物，其中R.sub.1代表氢、烷基、环烷基、苯基、苄基或苯乙基，R.sub.2代表烷基硫、烷基亚砜、烷基砜、苯硫、苯基亚砜、苯基砜、苄基硫、苄基亚砜或苄基砜，R.sub.3代表烷基、烷氧基、烷基硫或苯基，R.sub.4代表烷基，X代表氧或硫。制备它们的过程以及它们用于害虫控制的用途。
• METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM
  申请人：Toyo Ink Mfg. Co., Ltd

  公开号：EP1952918A1

  公开（公告）日：2008-08-06

  Disclosed is a method for producing a metal particle dispersion wherein a metal compound is reduced by using carbodihydrazide represented by the formula (1) below or a polybasic acid polyhydrazide represented by the formula (2) below (wherein R represents an n-valent polybasic acid residue) in a liquid medium. By reducing the metal compound in the presence of a compound having a function preventing discoloration of the metal, there can be obtained a metal particle dispersion having excellent discoloration preventing properties. Metal particles produced by such methods have a uniform particle diameter and are excellent in dispersion stability. By using a conductive resin composition or conductive ink containing a metal particle dispersion obtained by such production methods, there can be formed a conductive coating film, such as a conductive circuit or an electromagnetic layer, having good characteristics.

  本发明公开了一种生产金属颗粒分散液的方法，该方法通过在液体介质中使用下式 (1) 所代表的碳二酰肼或下式 (2) 所代表的多基酸多酰肼（其中 R 代表正价多基酸残基）还原金属化合物。通过在具有防止金属褪色功能的化合物存在下还原金属化合物，可获得具有优异防褪色性能的金属颗粒分散液。通过这种方法制得的金属颗粒具有均匀的颗粒直径和出色的分散稳定性。使用含有通过这种生产方法获得的金属颗粒分散体的导电树脂组合物或导电墨水，可以形成具有良好特性的导电涂膜，例如导电电路或电磁层。