actinorhodin | 1397-77-9

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: actinorhodin
• CAS: 1397-77-9
• 化学式: C₃₂H₂₆O₁₄
• 分子量: 634.55
• InChiKey: VTIKDEXOEJDMJP-WYUUTHIRSA-N

物化性质

• 沸点：
  1115.3±65.0 °C(Predicted)
• 密度：
  1.75±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.83
• 重原子数：
  46.0
• 可旋转键数：
  5.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  242.26
• 氢给体数：
  6.0
• 氢受体数：
  12.0

文献信息

• Compositions for controlled delivery of pharmaceutically active compounds
  申请人：Murthy V.S.N. Yerramilli

  公开号：US20060093632A1

  公开（公告）日：2006-05-04

  The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal by injection. When the pharmaceutical compositions are administered to an animal by injection, they form a drug depot that releases the pharmaceutically active compound over time. The pharmaceutical compositions can also be administered orally.

  该发明涉及提供药物组合物，该药物组合物提供药效活性化合物的持续释放，并且通过注射将药物组合物给动物以治疗或预防动物的某种疾病的方法。当将药物组合物通过注射给动物时，它们形成一个药物库，随着时间释放药效活性化合物。这些药物组合物也可以通过口服给予。
• Amino Acid Vitamin Ester Compositions for Controlled Delivery of Pharmaceutically Active Compounds
  申请人：Murthy Yerramilli V.S.N.

  公开号：US20090023678A1

  公开（公告）日：2009-01-22

  The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal. When the pharmaceutical compositions are administered to an animal by injection, they form a drug depot that releases the pharmaceutically active compound over time. The pharmaceutical compositions can also be administered orally.

  本发明涉及药物组合物，该组合物提供药物活性化合物的持续释放，并涉及通过将该药物组合物投与动物来治疗或预防某种疾病的方法。当该药物组合物通过注射方式投与动物时，它们形成一个药物沉积物，随着时间的推移释放药物活性化合物。该药物组合物也可以通过口服方式投与动物。
• [EN] ACTINORHODIN METAL SALTS, PROCESS FOR PREPARING THE SAME AND USES THEREOF<br/>[FR] SELS MÉTALLIQUES D'ACTINORHODINE, LEUR PROCÉDÉ DE PRÉPARATION ET LEURS UTILISATIONS
  申请人：PILI

  公开号：WO2021140179A1

  公开（公告）日：2021-07-15

  The present invention relates to a metal salt of actinorhodin or one of its derivatives, wherein the metal is selected from the group consisting of beryllium, magnesium, calcium, strontium, barium, copper, iron, aluminium, chromium, manganese, cobalt, nickel, zinc, and mixtures thereof. It also relates to a composition comprising such a metal salt, a process for preparing the same, and its use as a colouring agent or a pigment.

  本发明涉及一种放线菌红色素或其衍生物的金属盐，其中所述金属选自铍、镁、钙、锶、钡、铜、铁、铝、铬、锰、钴、镍、锌及其混合物。它还涉及包含该金属盐的组合物、其制备方法及其作为着色剂或颜料的用途。
• Bialaphos producing gene
  申请人：MEIJI SEIKA KABUSHIKI KAISHA

  公开号：EP0173327A2

  公开（公告）日：1986-03-05

  Disclosed are DNA strands comprising genes coding for the steps of biosynthesis of Bialaphos which is an antibiotic produced by Streptomyces hygroscopicus SF 1293, FERM BP-130/ATCC 21705, and is a fungicide/herbicide. A typical example of the DNA strands is in a hybrid plasmid pMSB 13-3 having a molecular weight of 41 kb and a restriction endonuclease cleavage site shown in Fig. 3.

  所公开的 DNA 链包含用于 Bialaphos 生物合成步骤的编码基因，Bialaphos 是一种抗生素，由 Streptomyces hygroscopicus SF 1293、FERM BP-130/ATCC 21705 生产，是一种杀真菌剂/除草剂。 DNA 链的一个典型例子是杂交质粒 pMSB 13-3，其分子量为 41 kb，限制性内切酶裂解位点如图 3 所示。
• Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases
  申请人：Proteotech Inc.

  公开号：EP1808169A2

  公开（公告）日：2007-07-18

  Polyhydroxylated aromatic compounds, and compositions containing them, are useful for the treatment of amyloidosis, especially Alzheimer's disease, and for the treatment of diseases characterized by α-synuclein fibril formation, especially Lewy body disease and Parkinson's disease.

  多羟基芳香族化合物和含有它们的组合物可用于治疗淀粉样变性病，特别是阿尔茨海默病，以及治疗以α-突触核蛋白纤维形成为特征的疾病，特别是路易体病和帕金森病。