N-pivaloyl-2-methyl aziridine | 92527-75-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-pivaloyl-2-methyl aziridine
• 英文别名: 2-methyl-1-pivaloylaziridine；N-pivaloyl-2-methylaziridine；2,2-Dimethyl-1-(2-methylaziridin-1-yl)propan-1-one
• CAS: 92527-75-8
• 化学式: C₈H₁₅NO
• 分子量: 141.213
• InChiKey: OEKGKXZPTFCSBP-UHFFFAOYSA-N

物化性质

• 沸点：
  55-56 °C(Press: 13 Torr)
• 密度：
  0.973±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  20.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-pivaloyl-2-methyl aziridine 、 苯基锂 以 四氢呋喃 为溶剂， 以82%的产率得到2,2,2-三甲基苯乙酮
  参考文献：
  名称：

  Convenient ketone synthesis n-acylaziridines

  摘要：

  DOI：

  10.1016/s0040-4039(01)80033-2
• 作为产物：
  描述：

  三甲基乙酰氯 、 2-甲基氮丙啶 在 三乙胺 作用下， 以 Petroleum ether 为溶剂， 反应 0.75h， 生成 N-pivaloyl-2-methyl aziridine
  参考文献：
  名称：

  Convenient ketone synthesis n-acylaziridines

  摘要：

  DOI：

  10.1016/s0040-4039(01)80033-2

文献信息

• Synthesis of the bis-potassium salts of 5-hydroxy-3-oxopent-4-enoic acids and their use for the efficient preparation of 4-hydroxy-2H-pyran-2-ones and other heterocycles
  作者：Dietmar Schmidt、J?rgen Conrad、Iris Klaiber、Uwe Beifuss

  DOI：10.1039/b611105j

  日期：——

  5-Hydroxy-3-oxopent-4-enoic acid esters can be efficiently transformed into the stable bis-potassium salts of the corresponding 5-hydroxy-3-oxopent-4-enoic acids, from which the sensitive acids are released in situ, the latter being converted into substituted 4-hydroxy-2H-pyran-2-ones, pyrazoles and isoxazoles under mild conditions; the efficiency of this method is demonstrated by the first synthesis

  可以将5-羟基-3-oxopent-4-enoic酸酯有效地转化为相应的5-hydroxy-3-oxopent-4-enoic酸的稳定双钾盐，敏感酸从该盐中就地释放出来，后者在温和条件下转化为取代的4-羟基-2H-吡喃-2-酮，吡唑和异恶唑；该方法的效率通过两种天然存在的吡喃酮的首次合成得到证明。
• N-Acyl-2-methylaziridines: Synthesis and utility in the C-acylation of β-ketoester derived dianions
  作者：Barry Lygo

  DOI：10.1016/0040-4020(95)00820-x

  日期：1995.11

  A “one pot” method for the preparation of N-acyl-2-methylaziridines is described, and the utility of these compounds in the C-acylation of dianions derived from β-ketoesters investigated. Application of this methodology to the synthesis of the polyketide natural product yangonin is also described.

  描述了用于制备N-酰基-2-甲基氮丙啶的“一锅法”，并且研究了这些化合物在衍生自β-酮酸酯的二价阴离子的C-酰化中的用途。还描述了该方法在聚酮化合物天然产物仰光宁合成中的应用。
• MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE
  申请人：Bridgestone Corporation

  公开号：EP1834966A1

  公开（公告）日：2007-09-19

  The present invention provides a modified polymer, which is obtained by reacting, with an active metal bonded to a polymer, a modifier represented by the general formula (I) (where X1 to X5 each represent a hydrogen atom or a specific monovalent functional group, and at least one of those is other than a hydrogen atom, R1 to R5 each represent a single bond or a divalent hydrocarbon group having 1 to 18 carbon atoms, and a plurality of aziridine rings may be bonded through any of X1 to X5 and R1 to R5). More particularly, the present invention provides a novel modified polymer which has excellent interaction with carbon black and enables improvement in dispersibility of the carbon black when used in a rubber composition blended with the carbon black, a rubber composition containing the modified polymer and capable of providing a tire excellent in low heat generating property, rupture characteristics, and abrasion resistance, and a tire made of the rubber composition and having the above-mentioned characteristics.

  本发明提供了一种改性聚合物，它是由通式(I)代表的改性剂（其中 X1 至 X5 各代表一个氢原子或一个特定的一价官能团，且其中至少有一个不是氢原子，R1 至 R5 各代表一个单键或一个具有 1 至 18 个碳原子的二价烃基，多个氮丙啶环可通过 X1 至 X5 和 R1 至 R5 中的任意一个键合）与键合在聚合物上的活性金属反应而得。更具体地说，本发明提供了一种新型改性聚合物，该聚合物与炭黑具有良好的相互作用，当用于与炭黑共混的橡胶组合物中时，可改善炭黑的分散性；本发明还提供了一种含有该改性聚合物的橡胶组合物，该橡胶组合物能够提供低发热性能、断裂特性和耐磨性优异的轮胎；本发明还提供了一种由该橡胶组合物制成的轮胎，该轮胎具有上述特性。
• MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES
  申请人：Bridgestone Corporation

  公开号：EP1873168A1

  公开（公告）日：2008-01-02

  The present invention provides a modified conjugated diene polymer that is prepared by polymerization of a conjugated diene compound using a catalyst containing a lanthanoid rare earth element compound in an organic solvent and then modifying the resulting polymer having an active organic metal site with a modifier, wherein the modification efficiency is not less than 15% and the cis-1,4 bond content in the conjugated diene moiety measured by Fourier transform infrared spectroscopy satisfies the relationship (I): or the modification efficiency is not less than 75% and the cis-1,4 bond content in the conjugated diene moiety measured by Fourier transform infrared spectroscopy satisfies the relationship (II): The invention further provides a rubber composition containing the modified conjugated diene polymer and giving a tire exhibiting low heat build-up, satisfactory failure characteristics, and high abrasion resistance, and a tire composed of the rubber composition and exhibiting these characteristics.

  本发明提供了一种改性共轭二烯聚合物，其制备方法是在有机溶剂中使用含有镧系稀土元素化合物的催化剂对共轭二烯化合物进行聚合，然后用改性剂对所得到的具有活性有机金属位点的聚合物进行改性，其中改性效率不低于 15%，通过傅里叶变换红外光谱法测量的共轭二烯分子中的顺式-1,4 键含量满足关系式（I）： 或改性效率不低于 75%，且通过傅里叶变换红外光谱法测量的共轭二烯分子中的顺式-1,4 键含量满足关系式（II）： 本发明进一步提供了一种含有改性共轭二烯聚合物的橡胶组合物，该组合物可提供一种具有低热积聚、令人满意的失效特性和高耐磨性的轮胎，以及一种由该橡胶组合物组成并具有上述特性的轮胎。
• RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE
  申请人：Bridgestone Corporation

  公开号：EP1975200A1

  公开（公告）日：2008-10-01

  A rubber composition comprises 10 to 70 parts by mass of carbon black having 20 to 100 m2/g of the specific surface area by nitrogen adsorption per 100 parts by mass of a rubber component comprising 20 to 80 parts by mass of a modified polybutadiene rubber and 80 to 20 parts by mass of natural rubber and/or at least one other diene-based synthetic rubber, wherein the modified polybutadiene is obtained by polymerizing 1,3-butadiene in an organic solvent using a compound having a rare earth element of the lanthanoid series, followed by modifying the obtained polybutadiene, and has a content of the cis-1,4-bond of 92% or greater, a content of vinyl bond of 1.5% or smaller and a fraction of the modified chain end of 20% or greater; and a tire using the rubber composition for a sidewall. The rubber composition exhibits excellent low heat buildup property and resistance to fracture.

  一种橡胶组合物，包括每 100 份质量的橡胶成分中含有 10 至 70 份质量的炭黑，其氮吸附比表面积为 20 至 100 m2/g，该橡胶成分包括 20 至 80 份质量的改性聚丁二烯橡胶和 80 至 20 份质量的天然橡胶和/或至少一种其他二烯基合成橡胶、其中，改性聚丁二烯是通过在有机溶剂中使用具有稀土元素的镧系化合物聚合 1,3-丁二烯，然后对所得到的聚丁二烯进行改性而得到的，其顺式-1,4-键的含量为 92% 或更高，乙烯基键的含量为 1.5%或更低，改性链端的比例为 20% 或更高；以及使用该橡胶组合物作为胎侧的轮胎。该橡胶组合物具有优异的低蓄热性能和抗断裂性能。