6-chloro-8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purine | 686344-50-3
中文名称
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中文别名
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英文名称
6-chloro-8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purine
英文别名
6-chloro-8-(2-chlorophenyl)-9-(4-chlorophenyl)purine
CAS
686344-50-3
化学式
C17H9Cl3N4
mdl
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分子量
375.644
InChiKey
BBXAXEFZCWOTRG-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
计算性质
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辛醇/水分配系数(LogP)：5.6
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重原子数：24
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可旋转键数：2
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环数：4.0
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sp3杂化的碳原子比例：0.0
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拓扑面积：43.6
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氢给体数：0
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氢受体数：3
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-ol 686344-49-0 C17H10Cl2N4O 357.199 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— N-{[4-(aminomethyl)cyclohexyl]methyl}-8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-amine 1450979-82-4 C25H26Cl2N6 481.428 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-N-(piperidin-4-yl)-9H-purin-6-amine 1408075-02-4 C22H20Cl2N6 439.347 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(piperidin-1-yl)-9H-purine 686346-28-1 C22H19Cl2N5 424.332 —— N-{[4-({[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}methyl)cyclohexyl]methyl}aminosulfonamide 1450979-63-1 C25H27Cl2N7O2S 560.507 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-9H-purine 686346-27-0 C22H20Cl2N6 439.347 —— N-{[4-({[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}methyl)cyclohexyl]methyl}methanesulfonamide 1450979-62-0 C26H28Cl2N6O2S 559.519 —— 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-amine 1408075-34-2 C22H20Cl2N6 439.347 —— 1-(4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidin-1-yl)ethan-1-one 1450979-67-5 C24H22Cl2N6O 481.384 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}acetamide 1408075-50-2 C24H22Cl2N6O 481.384 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-N-[(3R)-piperidin-3-yl]-9H-purin-6-amine 1408075-15-9 C22H20Cl2N6 439.347 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-N-[(3S)-piperidin-3-yl]-9H-purin-6-amine 1408075-24-0 C22H20Cl2N6 439.347 —— 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1λ6,4-thiomorpholine-1,1-dione 1450979-64-2 C21H17Cl2N5O2S 474.37 —— methyl N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}carbamate 1450979-79-9 C24H22Cl2N6O2 497.384 —— 4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl] amino}-N-ethylpiperidine-1-carboxamide 1408075-05-7 C25H25Cl2N7O 510.426 —— N-butyl-4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidine-1-carboxamide 1408075-10-4 C27H29Cl2N7O 538.48 —— 4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}-N-propylpiperidine-1-carboxamide 1408075-07-9 C26H27Cl2N7O 524.453 —— 1-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-ethylurea 1408075-37-5 C25H25Cl2N7O 510.426 —— 1-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-(propan-2-yl)urea 1408075-40-0 C26H27Cl2N7O 524.453 —— 1-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-propylurea 1408075-43-3 C26H27Cl2N7O 524.453 —— 3-butyl-1-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}urea 1408075-47-7 C27H29Cl2N7O 538.48 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(pyridin-4-ylmethyl)piperazin-1-yl]-9H-purine —— C27H23Cl2N7 516.433 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-2,2,2-trifluoroacetamide 1408075-57-9 C24H19Cl2F3N6O 535.356 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-N-(1-methanesulfonylpiperidin-4-yl)-9H-purin-6-amine 1408075-11-5 C23H22Cl2N6O2S 517.439 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-(piperidin-1-yl)propanamide 1450979-77-7 C30H33Cl2N7O 578.544 —— 4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}-N-(propan-2-yl)piperidine-1-carboxamide 1408075-06-8 C26H27Cl2N7O 524.453 —— tert-butyl 4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidine-1-carboxylate 1408075-01-3 C27H28Cl2N6O2 539.464 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}aminosulfonamide 1450979-68-6 C22H21Cl2N7O2S 518.426 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}cyclohexanecarboxamide 1450979-70-0 C29H30Cl2N6O 549.503 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(trifluoroacetyl)piperazin-1-yl]-9H-purine —— C23H17Cl2F3N6O 521.329 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}methanesulfonamide 1408075-54-6 C23H22Cl2N6O2S 517.439 —— tert-butyl N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}carbamate 1408075-33-1 C27H28Cl2N6O2 539.464 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-hydroxy-3-methylbutanamide —— C27H28Cl2N6O2 539.464 —— tert-butyl 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperazine-1-carboxylate —— C26H26Cl2N6O2 525.437 —— 3-{4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperazin-1-yl}phenol —— C27H22Cl2N6O 517.417 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-9H-purine —— C27H28Cl2N6O 523.465 —— 1-[(3S)-3-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidin-1-yl]ethan-1-one 1408075-29-5 C24H22Cl2N6O 481.384 —— 1-[(3R)-3-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidin-1-yl]ethan-1-one 1408075-20-6 C24H22Cl2N6O 481.384 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(ethylsulfonyl)piperazin-1-yl]-9H-purine —— C23H22Cl2N6O2S 517.439 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(1-pyridin-4-ylethyl)piperazin-1-yl]-9H-purine —— C28H25Cl2N7 530.459 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}benzamide 1408075-60-4 C29H24Cl2N6O 543.455 —— 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-N-(cyclohexylmethyl)piperazine-1-carboxamide —— C29H31Cl2N7O 564.517 —— N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-1,1,1-trifluoromethanesulfonamide 1450979-69-7 C23H19Cl2F3N6O2S 571.41 —— 1-[9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-ylamino]-cyclopentanecarboxylic acid 750570-63-9 C23H19Cl2N5O2 468.342 奥替那班 Otenabant 686344-29-6 C25H25Cl2N7O 510.426 —— 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-N-(4-fluorophenyl)piperazine-1-carboxamide —— C28H22Cl2FN7O 562.433 —— (3R)-3-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}-N-ethylpiperidine-1-carboxamide 1408075-18-2 C25H25Cl2N7O 510.426 —— (3S)-3-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}-N-ethylpiperidine-1-carboxamide 1408075-26-2 C25H25Cl2N7O 510.426 —— 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-N-(pyridin-2-yl)piperazine-1-carboxamide —— C27H22Cl2N8O 545.431 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-N-[(3R)-1-methanesulfonylpiperidin-3-yl]-9H-purin-6-amine 1408075-21-7 C23H22Cl2N6O2S 517.439 —— 8-(2-chlorophenyl)-9-(4-chlorophenyl)-N-[(3S)-1-methanesulfonylpiperidin-3-yl]-9H-purin-6-amine 1408075-30-8 C23H22Cl2N6O2S 517.439