2-hydroxyethyl-18-crown-6 | 1444616-42-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-hydroxyethyl-18-crown-6
• 英文别名: 1,4,7,10,13,16-Hexaoxacyclooctadecane-2-ethanol；2-(1,4,7,10,13,16-hexaoxacyclooctadec-2-yl)ethanol
• CAS: 1444616-42-5
• 化学式: C₁₄H₂₈O₇
• 分子量: 308.372
• InChiKey: YOYNSMFNGJCNFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  75.6
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-(2-Phenylmethoxyethyl)-1,4,7,10,13,16-hexaoxacyclooctadecane 在 5%-palladium/activated carbon 、 氢气 作用下， 以 乙醇 为溶剂， 20.0 ℃ 、101.3 kPa 条件下， 反应 48.0h， 以1.35 g的产率得到2-hydroxyethyl-18-crown-6
  参考文献：
  名称：

  新型 C-Pivot Lariat 18-Crown-6 醚的合成及其高效纯化

  摘要：

  介绍了各种套索醚的合成，包括以前未报道的几种及其有效纯化。合成路线汇集了来自各种先前工作的反应，从而为这些 C-pivot 套索提供了一种稳健而通用的方法。主要步骤是在钾作为模板阳离子的存在下将官能化二醇与二甲苯磺酸五乙二醇缩合。通过从氢氧化钾水溶液中萃取，无需色谱法即可实现最终产物的纯化。

  DOI：

  10.1055/s-0034-1378790

文献信息

• Electrophotographic photosensitive member, process cartridge, and electrophotographic image forming apparatus
  申请人：CANON KABUSHIKI KAISHA

  公开号：US11500301B2

  公开（公告）日：2022-11-15

  An electrophotographic photosensitive member, which is suppressed in occurrence of fogging and is excellent in abrasion resistance. In the electrophotographic photosensitive member, an outermost surface layer of the electrophotographic photosensitive member comprises a polymerized product of a composition comprising at least a polyrotaxane and a monomer having a polymerizable reactive group, and a chain molecule of the polyrotaxane has two blocking groups at both terminals thereof, and a (meth)acryloyloxy group of a cyclic molecule of the polyrotaxane forms a bond.

  一种电子照相感光构件，可抑制雾化现象的发生，并具有优异的耐磨性。在该电子照相感光构件中，电子照相感光构件的最外表层由一种组合物的聚合产物组成，该组合物至少包括一种聚二十六烷和一种具有可聚合反应基团的单体，聚二十六烷的链状分子在其两端具有两个封端基团，聚二十六烷的环状分子的（甲基）丙烯酰氧基形成一个键。
• ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20210240094A1

  公开（公告）日：2021-08-05

  An electrophotographic photosensitive member, which is suppressed in occurrence of fogging and is excellent in abrasion resistance. In the electrophotographic photosensitive member, an outermost surface layer of the electrophotographic photosensitive member comprises a polymerized product of a composition comprising at least a polyrotaxane and a monomer having a polymerizable reactive group, and a chain molecule of the polyrotaxane has two blocking groups at both terminals thereof, and a (meth)acryloyloxy group of a cyclic molecule of the polyrotaxane forms a bond.
• Synthesis of Novel C-Pivot Lariat 18-Crown-6 Ethers and Their Efficient Purification
  作者：Salvatore Lepore、Susovan Jana、Vallabh Suresh

  DOI：10.1055/s-0034-1378790

  日期：——

  The syntheses of various lariat ethers including several not previously reported and their efficient purification are presented. The synthesis route brings together reactions from a variety of previous works leading to a robust and generalized approach to these C-pivot lariats. The main steps are condensation of functionalized diols with pentaethylene glycol ditosylate in the presence of potassium

  介绍了各种套索醚的合成，包括以前未报道的几种及其有效纯化。合成路线汇集了来自各种先前工作的反应，从而为这些 C-pivot 套索提供了一种稳健而通用的方法。主要步骤是在钾作为模板阳离子的存在下将官能化二醇与二甲苯磺酸五乙二醇缩合。通过从氢氧化钾水溶液中萃取，无需色谱法即可实现最终产物的纯化。