potassium isethionate | 1561-99-5

• 物质功能分类: 化学试剂 - 有机试剂 - 磺酸盐/亚磺酸盐
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: potassium isethionate
• 英文别名: Potassium 2-hydroxyethanesulfonate；potassium;2-hydroxyethanesulfonate
• CAS: 1561-99-5
• 化学式: C₂H₅O₄S*K
• 分子量: 164.224
• InChiKey: DMNPUBKRNRRYMC-UHFFFAOYSA-M

物化性质

• 熔点：
  191-193°C
• 稳定性/保质期：
  在常温常压下保持稳定，应避免与氧化剂接触。

计算性质

• 辛醇/水分配系数(LogP)：
  -4.47
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  85.8
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 危险品标志：
  Xn
• 安全说明：
  S22,S24/25,S36
• 危险类别码：
  R40
• 海关编码：
  2905590090
• 储存条件：
  密封储存，应存放在阴凉、干燥的库房中。

SDS

Name:	Isethionic Acid Potassium Salt 98% (Titr.) Material Safety Data Sheet
Synonym:	None
CAS:	1561-99-5

Section 1 - Chemical Product MSDS Name:Isethionic Acid Potassium Salt 98% (Titr.) Material Safety Data Sheet
Synonym:None

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
1561-99-5	Ethanesulfonic Acid, 2-Hydroxy-, Monop	98	216-342-0

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1561-99-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C2H5KO4S
Molecular Weight: 164.22

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, oxides of potassium.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1561-99-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethanesulfonic Acid, 2-Hydroxy-, Monopotassiumsalt - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1561-99-5: No information available.
Canada
CAS# 1561-99-5 is listed on Canada's DSL List.
CAS# 1561-99-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1561-99-5 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  potassium isethionate 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Kohler, American Chemical Journal, 1898, vol. 20, p. 692

  摘要：

  DOI：
• 作为产物：
  描述：

  牛磺酸 在 potassium nitrite 、 水 、 溶剂黄146 作用下， 生成 potassium isethionate
  参考文献：
  名称：

  The Addition of Sodium Bisulfite to Alkylene Oxides

  摘要：

  DOI：

  10.1021/ja01301a014

文献信息

• N-Sulfo alkane amino alkane phosphoric acids and their alkali metal
  申请人：Benckiser-Knapsack GmbH

  公开号：US04216163A1

  公开（公告）日：1980-08-05

  Novel and highly advantageous N-sulfo alkane amino alkane phosphonic acids and their alkali metal salts are provided. Said phosphonic acids are produced by reacting an alkali metal salt of an amino phosphonic acid with a halo, preferably chloro, or hydroxy alkane sulfonic acid or their alkali metal salts in an alkaline medium, while heating. In place of the halo and especially chloro or hydroxy alkane sulfonic acid reactants, there can also be used compounds which are capable of producing hydroxy alkane sulfonates such as carbylsulfate or aldehydes or, respectively, ethylene oxide with alkali metal bisulfites or metasulfites. The reaction is preferably carried out in a molar proportion of about 1:1 to about 1:2. The novel compounds are excellent complexing or sequestering agents especially with respect to polyvalent metal ions. They are highly resistant against hydrolysis and high temperatures and are of a very high water solubility.

  提供了新颖且高效的N-磺酸烷基氨基磷酸和其碱金属盐。所述磷酸是通过将氨基磷酸的碱金属盐与卤素（优选氯）或羟基烷基磺酸或它们的碱金属盐在碱性介质中反应，并加热而制备的。在卤素，特别是氯或羟基烷基磺酸的反应物的位置，也可以使用能够产生羟基烷基磺酸盐的化合物，如羧酸酯或醛类，或分别与碱金属亚硫酸氢盐或亚硫酸盐反应的乙烯氧化物。反应最好在摩尔比约为1:1至约为1:2的比例下进行。这些新颖的化合物是优秀的络合或螯合剂，特别是对于多价金属离子。它们对水解和高温具有很高的抵抗力，并且具有非常高的水溶性。
• 一种直接法合成脂肪酰基氨基酸表面活性剂的方法
  申请人：张家港格瑞特化学有限公司

  公开号：CN111004156A

  公开（公告）日：2020-04-14

  本发明公开了一种直接法合成脂肪酰基氨基酸表面活性剂的方法，步骤如下：（1）将脂肪酸、甲胺、羟乙基磺酸盐加入到反应器中；（2）密闭反应器，缓慢升温至150~300℃；（3）保温反应2~10小时；（4）蒸馏除去未反应的甲胺；（5）处理得到成品。本发明选择脂肪酸、甲胺、羟乙基磺酸钠直接反应，过程不引入氯离子等杂质，直接反应得到了目标产物，这样就省去了酸化、成盐等纯化步骤，减少了含盐废水或者有机溶剂的使用和排放。且操作方便，易于实现工业化生产，所制得产品亦可根据实际需求改变其产品形式，提高产品的成本优势和应用便利性优势。
• Synthesis of 2-Substituted N-Nitrooxazolidines
  作者：A.S. Ermakov、E.Yu. Petrov、Yu.A. Strelemko、D.B. Vinogradov、V.A. Tartakovskii

  DOI：10.1007/s11178-005-0315-7

  日期：2005.8

  A method was developed for preparation of N-nitrooxazolidines functionally substituted in position 2 consisting in nitration of reaction products obtained from N-(2-hydroxyethyl)sulfamate and 2-substituted acetaldehydes.

  开发了一种制备2位功能取代的N-硝基恶唑烷的方法，该方法包括由N-(2-羟乙基)氨基磺酸酯和2-取代乙醛获得的反应产物的硝化。
• 66. Reactions of ethylene oxides. Part II. Reactions with thioamides, thiols, and inorganic sulphur salts
  作者：C. C. J. Culvenor、W. Davies、N. S. Heath

  DOI：10.1039/jr9490000278

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: S: MVol.B2, 7.6.2, page 953 - 957
  作者：

  DOI：——

  日期：——

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