m-(acetoxymethyl)anisole | 35480-26-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: m-(acetoxymethyl)anisole
• 英文别名: 3-methoxybenzyl acetate；meta-methoxybenzyl acetate；(3-methoxyphenyl)methyl acetate
• CAS: 35480-26-3
• 化学式: C₁₀H₁₂O₃
• 分子量: 180.203
• InChiKey: AVTYLLXTBWFTSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  m-(acetoxymethyl)anisole 在 六甲基磷酰三胺 、 五氯化磷 、 sodium amide 、 三氯氧磷 作用下， 以 二硫化碳 为溶剂， 反应 2.0h， 生成 (2-乙炔基-5-甲氧基苯基)甲醇
  参考文献：
  名称：

  Cobalt-mediated [2 + 2 + 2] cycloadditions en route to natural products: a novel total synthesis of steroids via the one-step construction of the B,C,D framework from an A-ring precursor

  摘要：

  DOI：

  10.1021/jo00139a012
• 作为产物：
  描述：

  间甲基苯甲醚 在 sodium persulfate 、 copper diacetate 、 sodium acetate 作用下， 以 溶剂黄146 为溶剂， 以14%的产率得到m-(acetoxymethyl)anisole
  参考文献：
  名称：

  Benzyl Acetates by Acetoxylation of Methylbenzenes using Peroxydisulfate as Oxidizing Agent

  摘要：

  DOI：

  10.1055/s-1980-29061

文献信息

• Reusable and efficient polyvinylpolypyrrolidone-supported triflic acid catalyst for acylation of alcohols, phenols, amines, and thiols under solvent-free conditions
  作者：Mahgol Tajbakhsh、Mahmoud Tajbakhsh、Samad Khaksar、Helia Janatian Gazvini、Marzieh Heidary

  DOI：10.1007/s00706-016-1897-1

  日期：2017.6

  prepared and fully characterized by FT-IR, TGA, and SEM. This super acidic solid catalyst shows high catalytic activity for selective acylation of alcohols, phenols, amines, and thiols with anhydrides under solvent-free conditions at room temperature. In addition, this method features an easy to handle solid super acid catalyst and an operationally simple procedure, affording the desired acylated products

  摘要制备了三氟甲磺酸官能化的聚乙烯基聚吡咯烷酮，并通过FT-IR，TGA和SEM对其进行了全面表征。这种超酸性固体催化剂在室温下在无溶剂条件下，对醇，酚，胺和硫醇与酸酐的选择性酰化反应具有很高的催化活性。另外，该方法的特征在于易于处理的固体超强酸催化剂和操作简单的步骤，以优异的产率提供了所需的酰化产物。 图形概要
• Acetylation of alcohols and phenols by zinc zirconium phosphate as an efficient heterogeneous catalyst under solvent-free conditions
  作者：Abdol Reza Hajipour、Hirbod Karimi、Morteza Karimzadeh

  DOI：10.1007/s00706-014-1222-9

  日期：2014.9

  AbstractAn efficient method for the acetylation of a wide range of alcohols as well as phenols with acetic anhydride in good to excellent yields under solvent-free conditions, using zinc zirconium phosphate as the catalyst was investigated. The catalyst was characterized by XRD, inductivity coupled plasma-optical emission spectroscopy, and scanning electron microscope. Products are easily isolated

  摘要在无溶剂条件下，以磷酸锌锆为催化剂，研究了一种有效的方法，可在无溶剂条件下以乙酸酐良好且优异的产率对多种醇和酚进行乙酰化。用XRD，电感耦合等离子体发射光谱和扫描电子显微镜对催化剂进行了表征。与现有方法相比，产品易于分离，并且操作流程温和绿色。 图形概要
• P₂O₅/Al₂O₃as an Efficient Heterogeneous Catalyst for the Acetylation of Alcohols, Phenols, Thiols, and Amines Under Solvent-Free Conditions
  作者：Amin Zarei、Abdol R. Hajipour、Leila Khazdooz

  DOI：10.1080/00397911.2010.492197

  日期：2011.5.4

  Abstract A convenient, rapid, and efficient method for the acetylation of alcohols, phenols, thiols, and amines has been developed by using acetic anhydride in the presence of a catalytic amount of P2O5 /Al2O3 under solvent-free conditions at room temperature. This reaction was studied under different conditions, and several solvents were examined for this conversion. However, in terms of reaction

  摘要 在室温无溶剂条件下，在催化量的 P2O5/Al2O3 存在下，使用乙酸酐开发了一种方便、快速、有效的乙酰化醇、酚、硫醇和胺的方法。在不同条件下研究了该反应，并针对该转化检查了几种溶剂。然而，在反应时间和收率方面，发现在无溶剂条件下进行反应时获得了最好的结果。没有观察到旋光醇的外消旋和糖的差向异构。采用无毒廉价的材料，后处理简单干净，反应时间短，产品收率好是该方法的优点。
• Sol–gel derived LaFeO3/SiO2 nanocomposite: synthesis, characterization and its application as a new, green and recoverable heterogeneous catalyst for the efficient acetylation of amines, alcohols and phenols
  作者：Saeed Farhadi、Kosar Jahanara、Asma Sepahdar

  DOI：10.1007/s13738-013-0377-3

  日期：2014.8

  measurements and was used as a heterogeneous catalyst for the efficient acetylation of amines, alcohols and phenols to the corresponding acetates using acetic anhydride under solvent-free conditions. Among the various substrates, acetylation of amines was preceded rapidly, so that an amine group could be selectively acetylated in the presence of alcoholic or phenolic hydroxyl groups by the appropriate

  载LaFeO 3 /的SiO 2纳米复合材料是由从金属硝酸盐和原硅酸四乙酯（TEOS）的溶胶-凝胶法合成的二氧化硅2资源。该纳米复合产品通过XRD，FT-IR，SEM和表面积测量进行了表征，并用作非均相催化剂，用于在无溶剂条件下使用乙酸酐将胺，醇和酚类有效乙酰化为相应的乙酸酯。在各种不同的底物，胺的乙酰化迅速之前，使胺基团可以有选择地在醇或酚羟基基团的存在通过反应时间的合适的选择乙酰化。催化剂也可以重复使用几次而不会损失活性。此外，LaFeO 3 / SiO 2纳米复合材料的催化活性高于纯LaFeO 3的催化活性。纳米粒子。该方法产率高，清洁，成本有效，与具有其他官能团的底物相容并且非常适合于实际的有机合成。
• Microwave-assisted rapid and efficient deprotection and direct esterification and silylation of MOM and EOM ethers catalyzed by [Hmim][HSO4] as a Brønsted acidic ionic liquid
  作者：Iraj Mohammadpoor-Baltork、Majid Moghadam、Shahram Tangestaninejad、Valiollah Mirkhani、Ahmad Reza Khosropour、Arsalan Mirjafari

  DOI：10.1007/s00706-010-0373-6

  日期：2010.10

  Abstract1-Methylimidazolium hydrogensulfate, [Hmim][HSO4], a Brønsted acidic room temperature ionic liquid, is used as a catalyst and reaction medium for facile and eco-friendly deprotection of methoxymethyl (MOM) and ethoxymethyl (EOM) ethers to their corresponding alcohols under thermal conditions (Δ) and microwave irradiation (MW). Furthermore, one-pot interconversion to the respective acetates and

  摘要布朗斯台德酸性室温离子液体1-甲基咪唑硫酸氢盐[Hmim] [HSO 4 ]被用作催化剂和反应介质，可对甲氧基甲基（MOM）和乙氧基甲基（EOM）醚进行简便且环保的脱保护醇在热条件（Δ）和微波辐射（MW）下。此外，还实现了一锅转化为各自的乙酸酯和三甲基甲硅烷基（TMS）醚。 图形概要