(2E)-N-(4-aminobutyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide | 26148-06-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (2E)-N-(4-aminobutyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
• 英文别名: N-trans-caffeoylputrescine；N-(E)-caffeoylputrescine；N-caffeoyl putrescine；N-caffeoylputrescine；caffeoylputrescine；paucine；(E)-N-(4-aminobutyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
• CAS: 26148-06-1
• 化学式: C₁₃H₁₈N₂O₃
• 分子量: 250.298
• InChiKey: KTZNZCYTXQYEHT-GQCTYLIASA-N

物化性质

• 沸点：
  545.5±50.0 °C(Predicted)
• 密度：
  1.233±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  95.6
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  TRANS-咖啡酸 、 四亚甲基二胺 在 N,N'-二环己基碳二亚胺 、 氢氧化钾 作用下， 以 吡啶 、 甲醇 为溶剂， 反应 30.0h， 以35.3%的产率得到(2E)-N-(4-aminobutyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
  参考文献：
  名称：

  Induction of Resistance against the Leafminer,Liriomyza trifolii, by Jasmonic Acid in Sweet Pepper

  摘要：

  甜椒（Capsicum annuum）成熟期的叶子对三叶斑潜蝇（Liriomyza trifolii）（双翅目，潜蝇科）具有很强的拒卵作用，而子叶则受到蛆虫的猛烈攻击。用50微米和100微米的茉莉酸（JA）溶液处理子叶，可使植物对潜蝇产生强烈的拒卵作用。对经过JA处理的子叶进行高效液相色谱分析，发现一种化合物可诱导积累。根据光谱分析和化学方法，这种诱导的化合物被确定为咖啡酰基腐胺（CP）。在用0、10、50和100微米的JA处理过的子叶中，CP的积累量分别为6.0、43.0、105和140微克/克鲜重。用CP处理子叶，可使三叶斑潜蝇的刺孔数量显著减少，表明JA处理通过诱导CP积累增强了其对潜蝇的拒卵作用。

  DOI：

  10.1271/bbb.70033

文献信息

• Avocado flesh and/or skin extract rich in polyphenols and cosmetic, dermatological and nutraceutical compositions comprising same
  申请人：Laboratoires Expanscience

  公开号：US11026441B2

  公开（公告）日：2021-06-08

  The invention relates to an avocado extract rich in polyphenols, containing at least 10% by weight of polyphenols, expressed in gallic acid equivalent relative to the dry extract obtained, wherein said polyphenols contain procyanidins, cafeic acid and cafeic acid derivatives, typically in a proportion of at least 70% by weight, expressed in gallic acid equivalent relative to the total polyphenol content by weight. The invention also relates to a composition comprising an extract according to the invention as active agent and a suitable excipient. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths. Finally, the invention relates to a cosmetic care process for the skin, the superficial body growths or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which consists in administering such a composition or such an extract.

  本发明涉及一种富含多酚的牛油果提取物，以没食子酸当量表示，含有至少 10%（按重量计）的多酚，其中所述的多酚包含原花青素、咖啡酸和咖啡酸衍生物，以没食子酸当量表示，相对于总多酚含量（按重量计）的比例通常至少为 70%（按重量计）。本发明还涉及一种组合物，该组合物由作为活性剂的本发明提取物和合适的赋形剂组成。本发明还涉及这样一种组合物或这样一种提取物，用于预防或治疗皮肤、粘膜或身体表层增生的疾病或病理状况。最后，本发明还涉及一种用于皮肤、身体表皮或粘膜的美容护理工艺，其目的是改善皮肤、粘膜或皮肤表皮的状况或外观，该工艺包括施用此类组合物或此类提取物。
• HIGH LEVEL ANTIOXIDANT-CONTAINING FOODS
  申请人：J.R. Simplot Company

  公开号：EP2038300A2

  公开（公告）日：2009-03-25
• COMPOSITIONS COMPRISING HYDROXYCINNAMIC ACID AND RELATED CONJUGATES, ANALOGUES AND DERIVATIVES, AND METHODS OF USE THEREOF
  申请人：Yeda Research and Development Co., Ltd.

  公开号：EP3652302A2

  公开（公告）日：2020-05-20
• High level antioxidant-containing foods
  申请人：Rommens Caius

  公开号：US20080134356A1

  公开（公告）日：2008-06-05

  The present invention relates to increasing at least one antioxidant level in a plant or plant product by expressing a polynucleotide that encodes a transcription factor, which is active in a flavonoid pathway. Overexpression of, for instance, a novel and newly-identified gene, the mCai gene, in a plant, results in increased accumulation of chlorogenic acid and other related phenolics, which, in turn, increases the levels of beneficial antioxidant in the plant.
• METHODS OF USING PLANTS CONTAINING THE GDHA GENE
  申请人：Fakhoury Ahmad M.

  公开号：US20100223693A1

  公开（公告）日：2010-09-02

  Disclosed are new effects of increased gdhA gene expression on plants that are susceptible to Aspergillus and Fusarium virguliforme infection. Plants transformed with the gdhA gene are resistant to aflatoxin accumulation following Aspergillus infection, and to root rot following F. virguliforme infection. The resistance to aflatoxin accumulation and root rot in gdhA + plants is coincident with drought tolerance and resistance of the plants to certain herbicides. Methods for controlling aflatoxin contamination and root rot in crop plants, and for screening plants putatively transformed with gdhA, are described.