[(3R)-1-[(2R,3R,4R,5S,6R)-2-[[(2R,3S,4R,5R,6R)-3-hydroxy-4-[(3R)-3-hydroxydecoxy]-5-(3-oxotetradecanoylamino)-6-phosphonooxyoxan-2-yl]methoxy]-6-(methoxymethyl)-3-(3-oxotetradecanoylamino)-5-phosphonooxyoxan-4-yl]oxydecan-3-yl] (Z)-dodec-5-enoate | 162679-36-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(3R)-1-[(2R,3R,4R,5S,6R)-2-[[(2R,3S,4R,5R,6R)-3-hydroxy-4-[(3R)-3-hydroxydecoxy]-5-(3-oxotetradecanoylamino)-6-phosphonooxyoxan-2-yl]methoxy]-6-(methoxymethyl)-3-(3-oxotetradecanoylamino)-5-phosphonooxyoxan-4-yl]oxydecan-3-yl] (Z)-dodec-5-enoate
• CAS: 162679-36-9
• 化学式: C₇₃H₁₃₆N₂O₂₂P₂
• 分子量: 1455.8
• InChiKey: GDODKYPBSZCPOO-XFMGTHRKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.4
• 重原子数：
  99
• 可旋转键数：
  66
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  348
• 氢给体数：
  8
• 氢受体数：
  22

文献信息

• Soft tissue implants and anti-scarring agents
  申请人：Hunter L. William

  公开号：US20050152941A1

  公开（公告）日：2005-07-14

  Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.

  软组织植入物（如乳房、胸肌、下巴、面部、唇部和鼻部植入物）与抗疤痕剂结合使用，以抑制动物体内植入物可能产生的疤痕。
• Implantable sensors and implantable pumps and anti-scarring agents
  申请人：Hunter L. William

  公开号：US20050152946A1

  公开（公告）日：2005-07-14

  Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.

  用于与组织接触的泵和传感器与抗疤痕剂（如细胞周期抑制剂）结合使用，以抑制在动物体内植入泵和传感器时可能出现的疤痕。
• Polymer compositions and methods for their use
  申请人：Hunter L. William

  公开号：US20050175665A1

  公开（公告）日：2005-08-11

  Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.

  包含抗纤维化剂和/或聚合物的组合物可用于各种医疗应用，包括预防手术粘连、治疗炎症性关节炎、治疗疤痕和瘢痕疙瘩、治疗血管疾病以及预防软骨流失。
• Electrical devices and anti-scarring agents
  申请人：Hunter L. William

  公开号：US20060282123A1

  公开（公告）日：2006-12-14

  Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
• SUBSTITUTED LIPOSACCHARIDES USEFUL IN THE TREATMENT AND PREVENTION OF ENDOTOXEMIA
  申请人：Christ William J.

  公开号：US20100227835A1

  公开（公告）日：2010-09-09

  Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.