(Z)-2-(4-chlorophenyl)-4-phenyl-3-phenylsulfanylbut-3-en-2-ol | 1454265-13-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (Z)-2-(4-chlorophenyl)-4-phenyl-3-phenylsulfanylbut-3-en-2-ol
• CAS: 1454265-13-4
• 化学式: C₂₂H₁₉ClOS
• 分子量: 366.911
• InChiKey: CRWDJWZBPCEPNM-PGMHBOJBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-(4-chlorophenyl)-4-phenylbut-3-yn-2-ol 、 苯硫酚 在 cerium(III) chloride 作用下， 以 neat (no solvent) 为溶剂， 反应 0.5h， 以95%的产率得到(Z)-2-(4-chlorophenyl)-4-phenyl-3-phenylsulfanylbut-3-en-2-ol
  参考文献：
  名称：

  Regio- and stereoselective synthesis of (Z)-2-Arylsulfanyl allylic alcohols using anhydrous CeCl3 as catalyst under solvent free conditions

  摘要：

  Anhydrous CeCl3 was successfully employed as catalyst for the synthesis of (Z)-2-Arylsulfanyl allylic alcohols from propargylic alcohols and thiols under solvent free conditions. The products were obtained in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.07.142

文献信息

• Regio- and stereoselective synthesis of (Z)-2-Arylsulfanyl allylic alcohols using anhydrous CeCl3 as catalyst under solvent free conditions
  作者：Claudio C. Silveira、Guilherme M. Martins、Samuel R. Mendes

  DOI：10.1016/j.tetlet.2013.07.142

  日期：2013.10

  Anhydrous CeCl3 was successfully employed as catalyst for the synthesis of (Z)-2-Arylsulfanyl allylic alcohols from propargylic alcohols and thiols under solvent free conditions. The products were obtained in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.