2,20-heneicosanedione | 13897-17-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,20-heneicosanedione
• 英文别名: heneicosane-2,20-dione；Heneicosan-2,20-dion；2,20-Heneicosanedione；henicosane-2,20-dione
• CAS: 13897-17-1
• 化学式: C₂₁H₄₀O₂
• 分子量: 324.547
• InChiKey: QVUDGDVMOGDNCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,21-bis-diazo-heneicosane-2,20-dione 在 盐酸 、 氯仿 、 溶剂黄146 、 锌 作用下， 生成 2,20-heneicosanedione
  参考文献：
  名称：

  Canonica; Bacchetti, Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1953, vol. <8>15, p. 278,281

  摘要：

  DOI：

文献信息

• Intercalation of Multiple Carbon Atoms between the Carbonyls of α-Diketones
  作者：Emily P. Balskus、José Méndez-Andino、Ruslan M. Arbit、Leo A. Paquette

  DOI：10.1021/jo010494y

  日期：2001.10.1

  beneficial effect of facilitating removal of ruthenium and phosphorus byproducts generated during the metathesis step. This chemistry conveniently lends itself to the controlled intercalation of multiple methylene groups between the carbonyl carbons of readily available alpha-diketones to deliver linear or cyclic products.

  在适当条件下，开链或环状α-二酮与特定的ω-烯基有机金属的反应容易导致键合至末端烯烃链的1,2-二醇。用1-苯基-1，2-丙二酮，联乙酰和环己烷-1，2-二酮，在THF水溶液中的烯丙基化在两个相邻的羰基上容易进行。对于环十二烷-1,2-二酮，必须求助于烯丙基溴化镁以完成第二阶段的缩合反应。格氏试剂也很好地用作联乙酰基一加合物的反应物。相反，单烯丙基化樟脑醌不愿与格利雅试剂偶联，并且仅在应用巴比尔型烷基锂反应时才发生反应。已经检查了这些产物的闭环复分解。在六元环形成的地方，可以直接在二醇上进行环化。当涉及较大的环时，只有在能够促进两个双键相互接近的结构预组织起作用时，二醇才会反应。为此目的，预先转化为环状碳酸酯具有相当大的实用性。在后一种情况下，必须在用四乙酸铅进行的二醇裂解步骤之前进行皂化。后一种试剂还显示出非常有利的作用，可促进除去复分解步骤中产生的钌和磷副产物。这种化学性质方便地使其易
• Amphotericin B. I. Carbon Skeleton, Ring Size, and Partial Structure¹
  作者：Arthur C. Cope、Udo Axen、Elizabeth P. Burrows、Jürgen Weinlich

  DOI：10.1021/ja00970a022

  日期：1966.9
• A PERCHLORATE SOLUTION IMPROVED IN SAFETY, AND A METHOD FOR HEAT-STABILIZING CHLORINE-CONTAINING RESIN COMPOSITIONS
  申请人：Akishima Chemical Industries Co., Ltd.

  公开号：EP2429940A1

  公开（公告）日：2012-03-21
• PERCHLORATE SOLUTION IMPROVED IN SAFETY, AND A METHOD FOR HEAT-STABILIZING CHLORINE-CONTAINING RESIN COMPOSITIONS
  申请人：Yoshino Kenji

  公开号：US20120123038A1

  公开（公告）日：2012-05-17

  To improve the handlability and safety of a perchlorate solution used as a stabilizer for chlorine-containing resins. This invention provides a perchlorate solution of improved handlability and safety and a method for heat-stabilizing chlorine-containing resin compositions by adding (a) 0.004 to 10 parts by weight of a perchlorate solution containing 1 to 60% by weight of perchlorate, 5 to 50% by weight of water-soluble organic solvent and 20 to 94% by weight of water, and (b) 0.001 to 10 parts by weight of at least one silicate compound represented by the general formula (I) to 100 parts by weight of a chlorine-containing resin: M(O)a nSiO 2 mH 2 O   (I) in which M is at least one metal selected from alkaline earth metals and aluminum, a is 1 when M is an alkaline earth metal and 3/2 where M is aluminum, n is from 1 to 5, and m is any positive integer.
• US4252698A
  申请人：——

  公开号：US4252698A

  公开（公告）日：1981-02-24