1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)prop-2-en-1-one | 24668-06-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)prop-2-en-1-one
• CAS: 24668-06-2
• 化学式: C₁₅H₁₁NO₅
• 分子量: 285.256
• InChiKey: PZNSXDODRVGONW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  100.67
• 氢给体数：
  2.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  2,4-二羟基苯乙酮 、 邻硝基苯甲醛 在 calcium hydroxide 作用下， 以 甲醇 为溶剂， 以61%的产率得到1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)prop-2-en-1-one
  参考文献：
  名称：

  Calcium Hydroxide Is an Efficient Catalyst for Synthesis of Polyhydroxy Chalcones

  摘要：

  Calcium hydroxide was found to be an efficient catalyst for synthesis of polyhydroxy chalcones. This method has been employed to synthesize various 2,4-dihydroxychalcones having various substituents on the B ring. The merits of this method include shorter reaction time, inexpensive and easily available catalyst, high yield, and easy workup compared to other reported methods.

  DOI：

  10.1080/15533174.2012.752392

文献信息

• Calcium Hydroxide Is an Efficient Catalyst for Synthesis of Polyhydroxy Chalcones
  作者：P. S. Kulkarni、P. M. Swami、P. K. Zubaidha

  DOI：10.1080/15533174.2012.752392

  日期：2013.1.1

  Calcium hydroxide was found to be an efficient catalyst for synthesis of polyhydroxy chalcones. This method has been employed to synthesize various 2,4-dihydroxychalcones having various substituents on the B ring. The merits of this method include shorter reaction time, inexpensive and easily available catalyst, high yield, and easy workup compared to other reported methods.