2-(2-(pent-4-enyloxy)ethoxy)ethanol | 753459-19-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(2-(pent-4-enyloxy)ethoxy)ethanol
• 英文别名: 2-(2-Pent-4-enoxyethoxy)ethanol
• CAS: 753459-19-7
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: UDCIGJCUYKFARL-UHFFFAOYSA-N

物化性质

• 沸点：
  251.2±25.0 °C(Predicted)
• 密度：
  0.955±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(2-(pent-4-enyloxy)ethoxy)ethanol 在 potassium carbonate 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 72.0h， 生成 3,4-bis(2-(2-(pent-4-en-1-yloxy)ethoxy)ethoxy)benzaldehyde
  参考文献：
  名称：

  Bifunctional [c2]Daisy-Chains and Their Incorporation into Mechanically Interlocked Polymers

  摘要：

  A strategy for the formation of mechanically interlocked polymers is presented. Ring-closing olefin metathesis has been shown to provide a very high yielding route to [c2]daisy-chains suitably functionalized to allow their one-step conversion to bisolefins which can be used as monomers in ADMET polymerizations to afford mechanically interlocked polymers. Metathesis, in two different guises is making a hitherto unreachable goal in synthesis a reality.

  DOI：

  10.1021/ja0725100
• 作为产物：
  描述：

  5-溴-1-戊烯 、 二乙二醇 在 sodium hydroxide 作用下， 以 水 为溶剂， 反应 24.0h， 以80%的产率得到2-(2-(pent-4-enyloxy)ethoxy)ethanol
  参考文献：
  名称：

  INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS

  摘要：

  本文描述了雏菊链大分子、二聚体和聚合物以及相关的组合物、材料、方法和系统。

  公开号：

  US20110065935A1

文献信息

• Synthesis of Small and Large Fused Bicyclic Compounds by Tandem Dienyne Ring-Closing Metathesis
  作者：Hyeon Park、You-Lee Hong、Yongjoo B. Kim、Tae-Lim Choi

  DOI：10.1021/ol101233k

  日期：2010.8.6

  A tandem ring-closing metathesis reaction using ruthenium catalyst was carried out to synthesize various fused bicyclic compounds containing both small and large rings. Fast ring-closure of the small ring and slow ring-closure of the large ring resulted in the formation of only one Isomer. Further manipulation such as the Diels-Alder reaction was carried out to prepare a complex molecule containing multiple rings of different sizes.
• Switching and Extension of a [c2]Daisy-Chain Dimer Polymer
  作者：Paul G. Clark、Michael W. Day、Robert H. Grubbs

  DOI：10.1021/ja905924u

  日期：2009.9.30

  We report the synthesis of a [c2]daisy-chain dimer via ruthenium-catalyzed ring-closing olefin metathesis. Confirmation of the interlocked nature of the structure was achieved through single-crystal X-ray diffraction analysis. The dimer could be readily switched from the bound to the unbound conformation by treatment with 3.0 equiv of KOH and subsequently reprotonated by treatment with 3.0 equiv of HPF6. Azide functionalization of the dimer enabled incorporation in linear step-growth polymer chains using the alkyne-azide "click" reaction. Get permeation chromatography coupled with multiangle laser light scattering analysis showed the polymers contained 22 dimers and had a radius of gyration of 14.8 nm. Acylation of the amines of the dimers sterically forced elongation of the interlocked units, and MALLS analysis of the polymer showed a 48% increase in the R-s (21.4 nm).
• The Exclusivity of Multivalency in Dynamic Covalent Processes
  作者：Jovica D. Badjić、Stuart J. Cantrill、Robert H. Grubbs、Erin N. Guidry、Raul Orenes、J. Fraser Stoddart

  DOI：10.1002/anie.200453963

  日期：2004.6.21
• US8299276B2
  申请人：——

  公开号：US8299276B2

  公开（公告）日：2012-10-30
• Bifunctional [c2]Daisy-Chains and Their Incorporation into Mechanically Interlocked Polymers
  作者：Erin N. Guidry、Jean Li、J. Fraser Stoddart、Robert H. Grubbs

  DOI：10.1021/ja0725100

  日期：2007.7.1

  A strategy for the formation of mechanically interlocked polymers is presented. Ring-closing olefin metathesis has been shown to provide a very high yielding route to [c2]daisy-chains suitably functionalized to allow their one-step conversion to bisolefins which can be used as monomers in ADMET polymerizations to afford mechanically interlocked polymers. Metathesis, in two different guises is making a hitherto unreachable goal in synthesis a reality.