4-Hydroxy-2,3,5,6-tetramethyl-4-prop-2-enylcyclohexa-2,5-dien-1-one | 71210-28-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Hydroxy-2,3,5,6-tetramethyl-4-prop-2-enylcyclohexa-2,5-dien-1-one
• CAS: 71210-28-1
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: WYJSXIUFCHRFMK-UHFFFAOYSA-N

物化性质

• 沸点：
  314.0±42.0 °C(Predicted)
• 密度：
  1.001±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  杜醌 、 烯丙基三甲基硅烷 在 bismuth(lll) trifluoromethanesulfonate 作用下， 以 二氯甲烷 为溶剂， 反应 0.33h， 以82%的产率得到4-Hydroxy-2,3,5,6-tetramethyl-4-prop-2-enylcyclohexa-2,5-dien-1-one
  参考文献：
  名称：

  Bi(OTf)3-catalyzed allylation of quinones with allyltrimethylsilane

  摘要：

  p-Quinones react smoothly with allyltrimethylsilane in the presence of 2 mol%, of Bi(OTf)(3) under mild reaction conditions to afford the corresponding allyl substituted benzene derivatives, p-allylquinols and allyl substituted 1,4-naphthoquinones in excellent yields with high regioselectivity. This method is very useful for the direct introduction of an allyl functionality onto a quinone moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)01130-4

文献信息

• Bi(OTf)3-catalyzed allylation of quinones with allyltrimethylsilane
  作者：J.S Yadav、B.V.S Reddy、T Swamy

  DOI：10.1016/s0040-4039(03)01130-4

  日期：2003.6

  p-Quinones react smoothly with allyltrimethylsilane in the presence of 2 mol%, of Bi(OTf)(3) under mild reaction conditions to afford the corresponding allyl substituted benzene derivatives, p-allylquinols and allyl substituted 1,4-naphthoquinones in excellent yields with high regioselectivity. This method is very useful for the direct introduction of an allyl functionality onto a quinone moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.