1,2-dimethoxy-1,1,2,2-tetrafluoroethane | 73287-23-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,2-dimethoxy-1,1,2,2-tetrafluoroethane
• 英文别名: 1,1,2,2-tetrafluoro-1,2-dimethoxyethane
• CAS: 73287-23-7
• 化学式: C₄H₆F₄O₂
• 分子量: 162.084
• InChiKey: YUVROHVXUDSJJU-UHFFFAOYSA-N

物化性质

• 熔点：
  252 °C
• 沸点：
  365 °C
• 密度：
  1.269 g/cm3(Temp: 40 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  全氟乙烷-1,2-二基二氟磺酸酯 、 硫酸二甲酯 在 cesium fluoride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 以66%的产率得到1,2-dimethoxy-1,1,2,2-tetrafluoroethane
  参考文献：
  名称：

  Fluoroaliphatic esters of fluorosulfonic acid. 2. Reaction of bis(fluorosulfato)perfluoroalkanes with cesium fluoride

  摘要：

  2,3-Bis(fluorosulfato) perfluoroalkanes split under the action of CsF in the absence of solvents, giving a mixture of alpha-fluorosulfatoperfluoro ketones, perfluoroalkene sulfates, and perfluoro alpha-diketones. The occurrence of these reactions in solutions results mainly in the formation of oxides of the corresponding fluoroolefins or products of their conversions. The reactions carried out are the first examples of nucleophilic substitution at a secondary carbon atom in a perfluorinated saturated chain.

  DOI：

  10.1007/bf00958252

文献信息

• Methyl hypofluorite (MeOF) reactions with various fluoroolefins
  作者：Tetsuya Suzuta、Takashi Abe、Akira Sekiya

  DOI：10.1016/s0022-1139(02)00163-x

  日期：2003.1

  The reaction of methyl hypofluorite (MeOF) with certain fluoroolefins, such as CF2CF2, CF2CFCF3, CF2CFOCF3, CF2CFOMe, CF2CClF, CF2CHF, CF2CH2, CHFCH2, CF2CFCFCF2, occurred in CD3CN or in the presence of NaF. Using neat MeOF in the presence of NaF was a novel method and gave good results. We observed that when more than three fluorine atoms are bonded to the CC double bond, the addition products

  甲基次氟化物的（MeOF）与某些氟烯烃，如CF反应2 CF 2，CF 2 CFCF 3，CF 2 CFOCF 3，CF 2 CFOMe，CF 2 CClF，CF 2 CHF，CF 2  CH 2，CHFCH 2，CF 2 CFCFCF 2，发生在CD 3 CN或氟化钠的存在。在NaF存在下使用纯净的MeOF是一种新颖的方法，并给出了良好的结果。我们观察到，当三个以上的氟原子键合到CC双键上时，可以以较高的收率获得加成产物。
• PROCESS FOR PREPARING FLUORINE-CONTAINING ALKOXYALKANE
  申请人：Nanno Tetsuo

  公开号：US20080306308A1

  公开（公告）日：2008-12-11

  A process for preparing a fluorine-containing alkoxyalkane represented by the general formula (1) R 1 —O—R 2 —O—R 3 where at least one of R 1 , R 2 and R 3 contains one or more fluorine atoms. An alcohol with the highest acidity selected from the group consisting of the compounds represented by the general formula (2) R 1 —OH, the general formula (3) R 3 —O—R 2 —OH, the general formula (4) R 1 —O—R 2 —OH, and the general formula (5) R 3 —OH is reacted with at least one selected from the group consisting of the compounds represented by the general formula (6) Lg-R 2 —O—R 3 , the general formula (7) Lg-R 1 , the general formula (8) Lg-R 3 , and the general formula (9) Lg-R 2 —O—R 1 where Lg represents an anionic leaving group in the presence of a basic compound.

  一种制备含氟烷氧烷的方法，其通式表示为（1）R1—O—R2—O—R3，其中R1、R2和R3中至少有一个含有一个或多个氟原子。从通式表示的化合物群中选择酸性最高的醇，该化合物群包括通式（2）R1—OH，通式（3）R3—O—R2—OH，通式（4）R1—O—R2—OH和通式（5）R3—OH中的至少一种，与通式表示的化合物群中的至少一种反应，该化合物群包括通式（6）Lg-R2—O—R3，通式（7）Lg-R1，通式（8）Lg-R3和通式（9）Lg-R2—O—R1，其中Lg代表存在碱性化合物的情况下的阴离子离去基团。
• ROGOVIK, V. M.;DELYAGINA, N. I.;MYSOV, E. I.;CHERSTKOV, V. F.;STERLIN, S.+, IZV. AN CCCP. CEP. XIM.,(1990) N, S. 2057-2063
  作者：ROGOVIK, V. M.、DELYAGINA, N. I.、MYSOV, E. I.、CHERSTKOV, V. F.、STERLIN, S.+

  DOI：——

  日期：——
• Fluoroaliphatic esters of fluorosulfonic acid. 2. Reaction of bis(fluorosulfato)perfluoroalkanes with cesium fluoride
  作者：V. M. Rogovik、N. I. Delyagina、E. I. Mysov、V. F. Cherstkov、S. R. Sterlin、L. S. German

  DOI：10.1007/bf00958252

  日期：1990.9

  2,3-Bis(fluorosulfato) perfluoroalkanes split under the action of CsF in the absence of solvents, giving a mixture of alpha-fluorosulfatoperfluoro ketones, perfluoroalkene sulfates, and perfluoro alpha-diketones. The occurrence of these reactions in solutions results mainly in the formation of oxides of the corresponding fluoroolefins or products of their conversions. The reactions carried out are the first examples of nucleophilic substitution at a secondary carbon atom in a perfluorinated saturated chain.

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