3-(butyltellanyl)propanal | 444144-95-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(butyltellanyl)propanal
• 英文别名: 3-Butyltellanylpropanal
• CAS: 444144-95-0
• 化学式: C₇H₁₄OTe
• 分子量: 241.788
• InChiKey: KTRNEFYHFIGRNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.92
• 重原子数：
  9
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-(butyltellanyl)propanal 在 sodium tetrahydroborate 、 lithium chloride 作用下， 以 四氢呋喃 为溶剂， 以85%的产率得到3-(butyltellanyl)propan-1-ol
  参考文献：
  名称：

  Hydrochalcogenation of activated olefines. Synthesis of functionalized dialkylchalcogenides

  摘要：

  Alkanethiols, selenols and tellurols are generated in situ by reaction of elemental sulfur, selenium and tellurium with commercial alkyllithiums, followed by reaction with deoxygenated water. The alkanechalcogenols react in situ with activated ole. ns in a Michael- type addition reaction. (c) 2008 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2008.06.014
• 作为产物：
  描述：

  正丁基锂 、 丙烯醛 在 碲化氢 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 生成 3-(butyltellanyl)propanal
  参考文献：
  名称：

  通过有机碲化合物形成碳-碳键

  摘要：

  Z乙烯基碲化物是通过在非还原条件下使用n -BuLi–Te–H 2 O作为加氢灭菌系统对炔烃进行加氢灭菌而制得的。相同的系统促进了含有吸电子基团的烯烃的加氢酯化反应。锂和有机碲酸镁可对乙烯基卤化物，磷酸盐，磺酸盐和乙酸盐进行乙烯基取代，从而独家生成Z乙烯基碲化物。碲化物用容易获得的有机金属试剂进行金属转移，从而得到有价值的合成基础材料（例如，有机锂和有机铜酸盐）。乙烯基碲化物与Pd催化下的炔烃或与有机铜酸盐的反应，使偶联产物保持了双键的几何形状。

  DOI：

  10.1016/s0022-328x(00)00828-7

文献信息

• β-Functionalized selenides and tellurides by hydrochalcogenation of olefins containing electron-withdrawing groups
  作者：Fabiano K. Zinn、Vinı́cius E. Righi、Silas C. Luque、Henrique B. Formiga、João V. Comasseto

  DOI：10.1016/s0040-4039(02)00095-3

  日期：2002.2

  Olerins conjugated to electron-withdrawing groups (e.g. CHO, RCO, CO2R, CN) react rapidly with alkylselenols and tellurols generated in situ to give the corresponding beta-chalcogeno aldehydes, ketones, esters and nitriles. beta-Telluroketones are transformed into beta-telluroketals, which are beta-lithiocarbonyl synthons. (C) 2002 Elsevier Science Ltd. All rights reserved.
• Functionalized organozincates and organocuprates derived from γ-hydroxytellurides in the preparation of 1,4-hydroxyketones
  作者：Jefferson L. Princival、Alcindo A. Dos Santos、João V. Comasseto

  DOI：10.1016/j.tetlet.2009.08.097

  日期：2009.11

  A C-O-dianionic zincate was generated by a Te/Li exchange reaction of an alkyltelluride, followed by Li/Zn transmetallation and reaction with methyllithium. The reaction between the enantiomerically pure (99% ee) (R)-dianionic zincate and benzoyl chloride led to 3-hydroxy-1-phenyl pentanone with total retention of the carbon configuration (99% ee). Similar results were obtained using the corresponding Lipshutz cyanocuprates. (C) 2009 Elsevier Ltd. All rights reserved.
• Hydrochalcogenation of activated olefines. Synthesis of functionalized dialkylchalcogenides
  作者：João V. Comasseto、Rogério A. Gariani、Jefferson L. Princival、Alcindo A. Dos Santos、Fabiano K. Zinn

  DOI：10.1016/j.jorganchem.2008.06.014

  日期：2008.8

  Alkanethiols, selenols and tellurols are generated in situ by reaction of elemental sulfur, selenium and tellurium with commercial alkyllithiums, followed by reaction with deoxygenated water. The alkanechalcogenols react in situ with activated ole. ns in a Michael- type addition reaction. (c) 2008 Elsevier B. V. All rights reserved.
• Carbon–carbon bond formation by means of organotellurium compounds
  作者：R Barrientos-Astigarraga

  DOI：10.1016/s0022-328x(00)00828-7

  日期：2001.3.30

  vinylic halides, phosphates, sulphonates and acetates leading to the Z vinylic telluride exclusively. Tellurides are transmetallated with easily available organometallic reagents to give valuable synthetic building blocks (e.g. organolithiums and organocuprates). Reaction of vinylic tellurides with alkynes under Pd catalysis or with organocuprates gives the coupling products with retention of the double bond

  Z乙烯基碲化物是通过在非还原条件下使用n -BuLi–Te–H 2 O作为加氢灭菌系统对炔烃进行加氢灭菌而制得的。相同的系统促进了含有吸电子基团的烯烃的加氢酯化反应。锂和有机碲酸镁可对乙烯基卤化物，磷酸盐，磺酸盐和乙酸盐进行乙烯基取代，从而独家生成Z乙烯基碲化物。碲化物用容易获得的有机金属试剂进行金属转移，从而得到有价值的合成基础材料（例如，有机锂和有机铜酸盐）。乙烯基碲化物与Pd催化下的炔烃或与有机铜酸盐的反应，使偶联产物保持了双键的几何形状。