6,17-Dihydroxy-9,14-dioxapentacyclo[10.8.0.02,11.03,8.015,20]icosa-3(8),4,6,15(20),16,18-hexaene-10,13-dione | 128327-73-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 3,4-二氢香豆素
• 英文名称: 6,17-Dihydroxy-9,14-dioxapentacyclo[10.8.0.02,11.03,8.015,20]icosa-3(8),4,6,15(20),16,18-hexaene-10,13-dione
• CAS: 128327-73-1；129172-82-3；129172-84-5；129388-88-1
• 化学式: C₁₈H₁₂O₆
• 分子量: 324.29
• InChiKey: XVWRLYUTADFFAM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  24
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  7-羟基香豆素 在 二苯甲酮 作用下， 以 丙酮 为溶剂， 反应 14.0h， 以64%的产率得到6,17-Dihydroxy-9,14-dioxapentacyclo[10.8.0.02,11.03,8.015,20]icosa-3(8),4,6,15(20),16,18-hexaene-10,13-dione
  参考文献：
  名称：

  PROCESS FOR PRODUCTION OF COUMARIN DIMER COMPOUND

  摘要：

  公开号：

  EP2147921B1

文献信息

• Controllably degradable compositions and methods
  申请人：MASSACHUSETTS INSTITUTE OF TECHNOLOGY

  公开号：US10736914B2

  公开（公告）日：2020-08-11

  Methods for treating, adhering, or sealing biological tissue are provided. The methods include combining solutions containing a polymer component and a dendrimer component capable of reacting with each other, and at least one of the components includes a substituent capable of photoreversible dimerization that can be reversibly dimerized. Drug delivery compositions and kits containing these two components also are provided.

  提供了用于处理、粘附或密封生物组织的方法。这些方法包括将含有聚合物成分和树枝状聚合物成分的溶液结合在一起，聚合物成分和树枝状聚合物成分能够相互反应，其中至少一种成分包括能够进行光可逆二聚化的取代基。此外，还提供了含有这两种成分的给药组合物和试剂盒。
• Acrylate coating compositions comprising a UV light cleavable cross-linking agent
  申请人：Monash University

  公开号：US11078368B2

  公开（公告）日：2021-08-03

  The present disclosure provides a coating composition for forming a coating that at least partially mobilizes in response to UV light, the composition comprising a monomer selected from acrylates, methacrylates and mixtures thereof, a cross-linking agent comprising two sub-units covalently bonded together, each sub-unit comprising an unsaturated group which is co-polymerisable with the monomer, wherein the two sub-units are adapted to dissociate in response to irradiation by UV light. The cross-linking agent may be present in the coating composition in an amount of less than 15 mol % of the total of the monomer and cross-linking agent.

  本公开提供了一种涂料组合物，用于形成在紫外线照射下至少部分移动的涂层，该组合物包括选自丙烯酸酯、甲基丙烯酸酯及其混合物的单体、交联剂，交联剂包括共价键合在一起的两个亚单元，每个亚单元包括可与单体共聚的不饱和基团，其中两个亚单元适于在紫外线照射下解离。交联剂在涂层组合物中的含量可低于单体和交联剂总量的 15 摩尔%。
• Controllably Degradable Compositions and Methods
  申请人：Massachusetts Institute of Technology

  公开号：US20150174156A1

  公开（公告）日：2015-06-25

  Methods for treating, adhering, or sealing biological tissue are provided. The methods include combining solutions containing a polymer component and a dendrimer component capable of reacting with each other, and at least one of the components includes a substituent capable of photoreversible dimerization that can be reversibly dimerized. Drug delivery compositions and kits containing these two components also are provided.
• ACRYLATE COATING COMPOSITIONS COMPRISING A UV LIGHT CLEAVABLE CROSS-LINKING AGENT
  申请人：Monash University

  公开号：US20190071574A1

  公开（公告）日：2019-03-07

  The present disclosure provides a coating composition for forming a coating that at least partially mobilizes in response to UV light, the composition comprising a monomer selected from acrylates, methacrylates and mixtures thereof, a cross-linking agent comprising two sub-units covalently bonded together, each sub-unit comprising an unsaturated group which is co-polymerisable with the monomer, wherein the two sub-units are adapted to dissociate in response to irradiation by UV light. The cross-linking agent may be present in the coating composition in an amount of less than 15 mol % of the total of the monomer and cross-linking agent.
• US8258318B2
  申请人：——

  公开号：US8258318B2

  公开（公告）日：2012-09-04