tetraethylene glycol mono-2-phenyl-2-propenyl ether | 515881-62-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: tetraethylene glycol mono-2-phenyl-2-propenyl ether
• 英文别名: tetraethyleneglycol mono-2-phenyl-2-propenyl ether；tetraethyleneglycol mono-2-phenyl-propenyl ether；tetraethylene-glycol-mono-2-phenyl-2-propenyl-ether；2-[2-[2-[2-(2-phenylprop-2-enoxy)ethoxy]ethoxy]ethoxy]ethanol
• CAS: 515881-62-6
• 化学式: C₁₇H₂₆O₅
• 分子量: 310.39
• InChiKey: JYCIRCLODGKLDZ-UHFFFAOYSA-N

物化性质

• 沸点：
  429.1±40.0 °C(Predicted)
• 密度：
  1.069±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  22
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-苯基-1-丙烯 在 N-溴代丁二酰亚胺(NBS) 、 溴苯 、 sodium hydride 作用下， 以 四氢呋喃 、 mineral oil 为溶剂， 反应 13.0h， 生成 tetraethylene glycol mono-2-phenyl-2-propenyl ether 、 tetraethylene glycol di-2-phenyl-2-propenyl ether
  参考文献：
  名称：

  嵌有聚合物的金纳米簇催化剂（PI-Au）的制备及其在硼酸，醇和甲硅烷基烯醇醚的好氧氧化反应中的应用

  摘要：

  制备了被称为聚合物嵌顿的方法固定化的非均相金纳米簇催化剂。可以在加热条件下交联的具有环氧化物和醇部分的聚苯乙烯衍生的聚合物用作其制备的载体。在NaBH 4溶液中还原阳离子金盐和聚合物。添加用于聚合物的不良溶剂，并且使聚合物沉淀并包封在金纳米簇表面与苯环的π电子之间具有弱但多重相互作用的金纳米簇。将聚合物胶囊在纯净的条件下加热，以提供非均相的金纳米簇催化剂。即聚合物包裹的金纳米团簇。如此制备的催化剂可用于苯基硼酸，醇和甲硅烷基烯醇醚的需氧氧化。我们发现，聚合物的选择，聚合物的优劣溶剂，金属负载量，交联的加热条件以及最终活化对于获得高活性催化剂都是至关重要的。

  DOI：

  10.1016/j.tet.2014.05.014

文献信息

• The Polymer Incarcerated Method for the Preparation of Highly Active Heterogeneous Palladium Catalysts
  作者：Ryo Akiyama、Shū Kobayashi

  DOI：10.1021/ja029146j

  日期：2003.3.1

  incarcerated (PI) method" for preparing a heterogeneous palladium catalyst has been developed. The method is operationally simple, and the Pd catalyst prepared (PI Pd) is highly active for hydrogenation, carbon-carbon, and carbon-oxygen bond-forming reactions. Remarkable points are that the activity of PI Pd is higher than that of homogeneous Pd catalysts and that PI Pd is recovered by simple filtration

  开发了一种名为“聚合物包埋（PI）法”的制备多相钯催化剂的新方法。该方法操作简单，制备的Pd催化剂(PI Pd)对加氢、碳-碳和碳-氧键形成反应具有高活性。值得注意的是，PI Pd的活性高于均相Pd催化剂，PI Pd通过简单过滤回收并重复使用多次而不会损失活性。该催化剂有望替代许多多相钯催化剂，尤其是Pd/C，常用于学术界和工业界，但回收困难。
• Palladium catalyst composition
  申请人：Kobayashi Shu

  公开号：US20060019822A1

  公开（公告）日：2006-01-26

  The present invention discloses 1) a catalyst composition consisting of a crosslinked organic polymer compound and a palladium catalyst, wherein said catalyst is physically carried on said crosslinked organic polymer compound, 2) a manufacturing method of the above catalyst composition 1), characterized by homogenizing a straight chain organic polymer compound, having a crosslinkable functional group, and a palladium catalyst in a solvent dissolving said straight chain organic polymer compound, then depositing a composition thus formed and subjecting the crosslinkable functional group in said deposit to a crosslinking reaction, 3) a method for substitution reaction at an allyl position, characterized by reacting an allyl carbonate and a neucleophilic agent in the presence of the above catalyst composition 1), and 4) a method for oxidizing an alcohol, characterized by subjecting the above catalyst composition 1) to reaction with an alcohol. The catalyst composition of the present invention can be safely and easily handled without danger of spontaneous ignition, and the like, and is extremely useful as a catalyst for various chemical reactions, and further activity thereof is not decreased by repeated use thereof and a metal catalyst does not leak from a polymer compound which is a carrier thereof.

  本发明揭示了以下内容：1）由交联有机聚合物化合物和钯催化剂组成的催化剂组合物，其中所述催化剂物理上载在所述交联有机聚合物化合物上，2）上述催化剂组合物1）的制造方法，其特征在于在溶解所述直链有机聚合物化合物的溶剂中均质化具有可交联功能基团的直链有机聚合物化合物和钯催化剂，然后沉积形成的组合物并使所述沉积物中的可交联功能基团发生交联反应，3）一种在烯丙基位置进行取代反应的方法，其特征在于在上述催化剂组合物1）的存在下，将烯丙基碳酸酯和亲核试剂反应，4）一种氧化醇的方法，其特征在于将上述催化剂组合物1）与醇反应。本发明的催化剂组合物可以安全、容易地处理，没有自发着火等危险，并且极其有用作为各种化学反应的催化剂，其活性不会因重复使用而降低，并且金属催化剂不会从作为载体的聚合物化合物中泄漏。
• Polymer-Supported Metal Cluster Composition
  申请人：Kobayashi Shu

  公开号：US20080058200A1

  公开（公告）日：2008-03-06

  The objective is to present compositions obtained by supporting by polymers micro clusters of transition metals and the like that are useful as catalysts in various reactions and, once used, are readily recovered and reused. A polymer-supported metal cluster composition is obtained by supporting a transition metal by a cross-linked polymer, and the polymer-supported cluster composition is characterized by the cross-linked polymer obtained by cross-linking of a cross-linkable polymer containing a hydrophilic side chain and a hydrophobic side chain group having a cross-linkable functional group. This polymer-supported metal cluster composition is, for example, preferably formed by first forming a micelle composed of the metal clusters supported by the cross-linkable polymer in a suitable solution and subsequently subjecting the cross-linkable polymer to a cross-linking reaction. The composition is useful as a catalyst and the like in hydrogenation reactions, dehydrogenation reactions, allylic substitution reactions, oxidation reactions, coupling reactions and carbonylation reactions.

  本文旨在介绍由聚合物微团簇支持的过渡金属等组成的化合物，这些化合物在各种反应中作为催化剂有用，并且一旦使用后，可以轻松地回收和再利用。通过将过渡金属通过交联聚合物支持，可以获得聚合物支持的金属簇组成物，该聚合物支持的簇组成物的特征是通过交联可交联聚合物得到的交联聚合物，该可交联聚合物含有具有可交联功能基团的亲水侧链和疏水侧链基团。例如，可以首先在适当的溶液中形成由交联可交联聚合物支持的金属簇组成的胶束，然后对可交联聚合物进行交联反应，从而形成该聚合物支持的金属簇组成物。该组成物在氢化反应、脱氢反应、烯丙基取代反应、氧化反应、偶联反应和羰基化反应等中作为催化剂等有用。
• Polymer incarcerated lewis acid metal catalyst
  申请人：Kobayashi Shu

  公开号：US20070191624A1

  公开（公告）日：2007-08-16

  The objective is to incarcerate a Lewis acid metal in a polymer and to make this catalyst recoverable while maintaining its function as a Lewis acid metal catalyst. The present invention is a polymer-incarcerated Lewis acid metal catalyst in which a Lewis acid metal is incarcerated in a crosslinked polymer and the crosslinked polymer is crosslinked using the crosslinking groups contained in a crosslinkable polymer. The polymer incarcerated Lewis acid metal catalyst is characterized by the crosslinkable polymer containing at least one type of monomer unit containing hydrophobic substituents and hydrophilic substituents containing crosslinking groups, and the hydrophobic substituents contain aromatic substituents. This crosslinkable polymer preferably comprises at least one type of monomer unit containing hydrophobic substituents and hydrophilic substituents containing crosslinking groups and a monomer unit containing hydrophobic substituents. This catalyst can be obtained by subjecting a polymer micelle incarcerated Lewis acid metal obtained by mixing an organic solution containing a crosslinkable polymer and a Lewis acid metal with a bad solvent to a crosslinking reaction. This catalyst is useful as a catalyst in aldol reactions, cyanolation reactions, allylation reactions, Michael reactions, Mannich reactions, Diels Alder reactions and Friedel Crafts reactions.

  本发明的目的是将Lewis酸金属固定在聚合物中，并使该催化剂可回收，同时保持其作为Lewis酸金属催化剂的功能。本发明提供了一种聚合物固定的Lewis酸金属催化剂，其中Lewis酸金属被固定在交联聚合物中，交联聚合物使用可交联聚合物中所含的交联基团进行交联。该聚合物固定的Lewis酸金属催化剂的特点是可交联聚合物含有至少一种含有疏水取代基和含有交联基团的亲水取代基的单体单元，并且疏水取代基含有芳香取代基。该可交联聚合物最好包括至少一种含有疏水取代基和含有交联基团的亲水取代基的单体单元和一种含有疏水取代基的单体单元。该催化剂可通过将含有可交联聚合物和Lewis酸金属的有机溶液与劣溶剂混合后进行交联反应得到。该催化剂在Aldol反应、氰化反应、烯丙基化反应、Michael反应、Mannich反应、Diels Alder反应和Friedel Crafts反应中是有用的催化剂。
• METHOD FOR PRODUCING CARBONYL COMPOUND, CATALYST, AND METHOD FOR PRODUCING CATALYST
  申请人：Kobayashi Shu

  公开号：US20120029241A1

  公开（公告）日：2012-02-02

  The method for producing a carbonyl compound according to the invention comprises a step of obtaining a carbonyl compound by oxidation of a secondary alcohol in the presence of a catalyst, wherein the catalyst comprises a carrier obtained by the use of a styrene-based polymer with side chains containing crosslinkable functional groups, wherein the crosslinkable functional groups in the carrier are crosslinked, gold-platinum nanosize clusters supported on the carrier and carbon black supported on the carrier. The production method allows production of a carbonyl compound by oxidation of a secondary alcohol, with high selectivity and a high conversion rate.

  根据本发明，生产羰基化合物的方法包括以下步骤：在催化剂的存在下通过氧化二级醇来获得羰基化合物，其中催化剂包括通过使用含有可交联功能基的侧链的苯乙烯基聚合物获得的载体，其中载体中的可交联功能基已经交联，金铂纳米尺寸团簇支持在载体上和碳黑支持在载体上。该生产方法允许通过氧化二级醇来生产羰基化合物，具有高选择性和高转化率。